Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Injection and electroporation apparatus for drug and gene delivery










Image Number 2 for United States Patent #5273525.

An apparatus for implanting macromolecules such as genes, DNA or pharmaceuticals into a preselected tissue region such as a muscle or an organ of a patient. A modified syringe is provided for injecting a predetermined quantity of a fluid medium carrying the preselected macromolecules. A signal generator is connected to the syringe for generating a predetermined electric signal. The syringe includes a pair of electrodes which are connected to the signal generator for applying an electric field in the tissue region. The field has a predetermined strength and duration in order to make the walls of a plurality of cells in the tissue region transiently permeable to permit the macromolecules to enter said preselected cells without damaging said cells. This enhances the uptake of macromolecules and thus enhances the therapeutic effect achieved. Alternate embodiments having twin needles and a blade may be utilized.








 
 
  Recently Added Patents
Semiconductor device having germanium active layer with underlying parasitic leakage barrier layer
Device and method for unified codes
Scalable encoding apparatus, scalable decoding apparatus, scalable encoding method, scalable decoding method, communication terminal apparatus, and base station apparatus
Organic compounds
Thermoplastic fluoropolymer composition
Hermetically sealed atomic sensor package manufactured with expendable support structure
Storage basket with lid
  Randomly Featured Patents
Vinyl 4-tetrahydropyranyloxybenzal-vinyl 4-hydroxybenzal-vinyl tetrahydropyranyl ether-vinyl acetate copolymer, vinyl 4-tetrahydropyranyloxybenzal-vinyl tetrahydropyranyl ether-vinyl aceta
Method of operating a hearing device and a hearing device
Liquid crystal display apparatus
Method and apparatus for preventing piracy of digital content
Collapsible step stool with step movement guide system
Methods and apparatus for contextual awareness in a groupware client
Apparatus for cutting and conveying planar workpieces
Microfabricated rotary motion wobble motor and disk drive incorporating it
Aircraft
Disc case