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Method and composition to inhibit the growth of Streptococcus mutans by the use of saccharin/fluoride combination

Image Number 2 for United States Patent #4419346.

A method and composition for treating teeth to reduce dental caries is provided wherein the teeth are contacted with a synergistic combination of a saccharin material, and a fluoride material, for example, as contained in a chewing gum composition, the combination of saccharin material and fluoride material being present in an amount sufficient to inhibit growth of Streptococcus mutans in the presence of a fermentable carbohydrates in the oral cavity.

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