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Class Information
Number: 800/3
Name: Multicellular living organisms and unmodified parts thereof and related processes > Method of using a transgenic nonhuman animal in an in vivo test method (e.g., drug efficacy tests, etc.)
Description: Method wherein there is a direct or indirect qualitative or quantitative measurement or test involving a transgenic nonhuman animal where the actual test step must occur in or on the animal.

Patents under this class:
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Patent Number Title Of Patent Date Issued
8710294 Transparent zebrafish and preparation method thereof Apr. 29, 2014
8704037 Targeted cell death Apr. 22, 2014
8692051 Methods for testing for caloric restriction (CR) mimetics Apr. 8, 2014
8692052 Genetically modified mice and engraftment Apr. 8, 2014
8674172 Prostate cancer cell lines and their use in screening method Mar. 18, 2014
8663986 Cloned transmembrane receptor for 24-hydroxylated vitamin D compounds and uses thereof Mar. 4, 2014
8658133 Methods and compositions relating to alzheimer's disease Feb. 25, 2014
8629318 Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation Jan. 14, 2014
8624079 Knockin mouse with a disruption in a PXR gene expressing human PXR Jan. 7, 2014
8597615 Methods of monitoring a human anti-human antibody response and inhibitors thereof Dec. 3, 2013
8592642 Evaluation/screening method for diseases associated with D-amino acid utilizing DAO1-/-mouse Nov. 26, 2013
8558055 Genetically modified rat comprising a cytokine gene disruption and exhibiting a greater susceptibility to a cytokine-mediated autoimmune and/or inflammatory disease Oct. 15, 2013
8552253 Screening of drug for attention deficit hyperactive disorder by using GIT1 knock-out mice as a novel ADHD mouse model Oct. 8, 2013
8546643 Pig model for atherosclerosis Oct. 1, 2013
8541646 Genetically modified mice and engraftment Sep. 24, 2013
8524976 Iduronidase knock-out mouse Sep. 3, 2013
8524975 Method of predicting a behavior of one or more drugs Sep. 3, 2013
8513484 Fish cancer model Aug. 20, 2013
8512678 Non-invasive, in vivo fluorescent imaging of the nervous system in whole living animal Aug. 20, 2013
8502016 Genomic alpha synuclein transgenic animal Aug. 6, 2013
8502017 Rodent model of central neuropathic pain Aug. 6, 2013
8492610 Transgeneic animal expressing a multiple mutated form of presenilin 1 Jul. 23, 2013
8476484 Transgenic clawed frog embryos and use thereof as detectors of endocrine disrupters in the environment Jul. 2, 2013
8476485 Non-human animal model for amyotrophic lateral sclerosis (ALS) with loss-of-TDP-43 function Jul. 2, 2013
8470594 Methods for identifying agents that affect the survival of motor neurons Jun. 25, 2013
8466338 Identification of a JAK2 mutation involved in vaquez polyglobulia Jun. 18, 2013
8466340 Mouse model for pompe disease and methods of use thereof Jun. 18, 2013
8466339 Mig-6 knockout mice and elucidation of association of Mig-6 with early onset degenerative joint disease and role as a tumor suppressor Jun. 18, 2013
8445745 Animal model having a chimeric human liver and susceptible to human hepatitis C virus infection May. 21, 2013
8440412 Compositions, methods and animal models for screening therapeutics for TH2-type disease May. 14, 2013
8435488 Methods and compositions for protein labelling May. 7, 2013
8436224 Methods for testing for caloric restriction (CR) mimetics May. 7, 2013
8431768 Targeted and regional cellular ablation in zebrafish Apr. 30, 2013
8431767 Transgenic non-human animal and methods for stem cell engraftment Apr. 30, 2013
8420886 Transgenic mouse comprising a disrupted Fibulin-4 gene as a model for cardiovascular disease Apr. 16, 2013
8420885 Determining the capability of a test compound to affect solid tumor stem cells Apr. 16, 2013
8420884 Models of malignant brain cancer, and therapeutic siRNAs against oncogenic signaling pathways, and methods and kits for uses therefor Apr. 16, 2013
8415106 Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination Apr. 9, 2013
8395018 Transgenic fish and uses thereof Mar. 12, 2013
8389792 Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer and screening methods to identify same Mar. 5, 2013
8389794 Transgenic pig as a model of Alzheimer's disease Mar. 5, 2013
8367364 Methods of screening an agent for an activity in an isolated eye of a teleost Feb. 5, 2013
8367887 Normal-tension glaucoma model and method for evaluation of test substances by using same Feb. 5, 2013
8357832 F1B-TMIR plasmid vector and transgenic mouse Jan. 22, 2013
8324447 Chimeric avian-based screening system containing mammalian grafts Dec. 4, 2012
8324450 Non-human animal model for frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) Dec. 4, 2012
8319007 Mouse models with enhanced essential tremor and preparation method thereof Nov. 27, 2012
8309792 Non-human gene-disrupted animal with disrupted ADAM11 gene Nov. 13, 2012
8309790 Animal models for demyelination disorders Nov. 13, 2012
8304601 Mouse model for eye disease Nov. 6, 2012

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