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Class Information
Number: 546/45
Name: Organic compounds -- part of the class 532-570 series > Organic compounds (class 532, subclass 1) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., oxygen, sulfur, selenium, or tellurium) or nitrogen as the only ring hetero atoms (class 540, subclass 1) > Hetero ring is six-membered consisting of one nitrogen and five carbons > Polycyclo ring system having the six-membered hetero ring as one of the cyclos > Pentacyclo ring system having the six-membered hetero ring as one of the cyclos > Two of the cyclos share at least three ring members (i.e., bridged) > One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.) > Nitrogen or divalent chalcogen double bonded directly to carbocyclic ring of the pentacyclo ring system (e.g., morphinones, etc.)
Description: Compounds wherein a nitrogen atom or a divalent chalcogen (i.e., oxygen, sulfur, selenium, or tellurium) is attached directly by a double bond to a carbocyclic ring of the pentacyclo ring system.
Patents under this class:
| Patent Number |
Title Of Patent |
Date Issued |
| 5981751 |
Method for removal of residual organic solvents and use thereof in manufacturing pharmaceuticals |
Nov. 9, 1999 |
| 5977326 |
Process for making morphine-6-glucuronide or substituted morphine-6-glucuronide |
Nov. 2, 1999 |
| 5972953 |
Brain cell protective agent |
Oct. 26, 1999 |
| 5952495 |
Preparation of 14-hydroxynormorphinones from normorphinones |
Sep. 14, 1999 |
| 5948788 |
Normorphine and normorphinone derivatives |
Sep. 7, 1999 |
| 5922876 |
Preparation of oxymorphone from morphine |
Jul. 13, 1999 |
| 5886001 |
Agonist compounds |
Mar. 23, 1999 |
| 5869669 |
Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates |
Feb. 9, 1999 |
| 5847142 |
Preparation of narcotic analgesics |
Dec. 8, 1998 |
| 5783583 |
17-(cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol, hydrochloride salt for the purpose of rapid narcotic detoxification |
Jul. 21, 1998 |
| 5736573 |
Lipid and water soluble derivatives of drugs |
Apr. 7, 1998 |
| 5648359 |
Tumor necrosis factor production inhibitors |
Jul. 15, 1997 |
| 5607940 |
Morphine formulations for use by electromotive administration |
Mar. 4, 1997 |
| 5525727 |
Brain-specific drug delivery |
Jun. 11, 1996 |
| 5387264 |
Method for dyeing or coloring organic macromolecular substance by using coumarin compound or coloring material |
Feb. 7, 1995 |
| 5366979 |
Orally active nonaddicting analgesics |
Nov. 22, 1994 |
| 5352680 |
Delta opioid receptor antagonists to block opioid agonist tolerance and dependence |
Oct. 4, 1994 |
| 5260441 |
Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
Nov. 9, 1993 |
| 5258512 |
Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
Nov. 2, 1993 |
| 5232926 |
Morphinane-skeletoned hydrazone derivatives |
Aug. 3, 1993 |
| 5112975 |
Preparation of noroxymorphone from morphine |
May. 12, 1992 |
| 5071985 |
Process for the preparation of morphinane derivatives |
Dec. 10, 1991 |
| 4939264 |
Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
Jul. 3, 1990 |
| 4925848 |
Derivative of codeine useful as an agonist and process for the preparation of it |
May. 15, 1990 |
| 4912114 |
Morphinan derivatives |
Mar. 27, 1990 |
| 4889860 |
Oximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists |
Dec. 26, 1989 |
| 4806556 |
Gut-selective opiates |
Feb. 21, 1989 |
| 4803208 |
Opiate agonists and antagonists |
Feb. 7, 1989 |
| 4795813 |
Synthesis of derivatives of codeine and other 3-O-alkylmorphines |
Jan. 3, 1989 |
| 4767718 |
Fluorescent opioid reagents and methods of use thereof in the detection of opioid receptors |
Aug. 30, 1988 |
| 4760069 |
Oximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists |
Jul. 26, 1988 |
| 4749706 |
Orally active nonaddicting analgesics |
Jun. 7, 1988 |
| 4730048 |
Gut-selective opiates |
Mar. 8, 1988 |
| 4727146 |
Synthesis of chiral 1-benzyl-1,2,3,4-tetra-hydroisoquinolines by asymmetric reduction |
Feb. 23, 1988 |
| 4673679 |
Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration |
Jun. 16, 1987 |
| 4668685 |
Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists |
May. 26, 1987 |
| 4667037 |
Dealkylation of opioid ethers |
May. 19, 1987 |
| 4639520 |
Preparation of 14-hydroxy-N-ethoxy-carbonyl-norcodeinone |
Jan. 27, 1987 |
| 4613668 |
Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl |
Sep. 23, 1986 |
| 4608376 |
Opiate agonists and antagonists |
Aug. 26, 1986 |
| 4521601 |
Practical total synthesis unnatural enantiomers of opium-derived morphinans |
Jun. 4, 1985 |
| 4477456 |
Octahydro-4A,7-ethano- and -etheno-benzofuro[3,2-e]isoquinoline derivatives having analgesic, narcotic antagonist and anorexigenic properties |
Oct. 16, 1984 |
| 4473573 |
N-(2-methoxyethyl)-noroxymorphone and pharmaceutical compositions for relieving pain containing same |
Sep. 25, 1984 |
| 4472253 |
Process for the preparation of an N-substituted 3-O-alkyl-14-hydroxynormorphinone derivative |
Sep. 18, 1984 |
| 4464378 |
Method of administering narcotic antagonists and analgesics and novel dosage forms containing same |
Aug. 7, 1984 |
| 4451470 |
Analgesic, antagonist, and/or anorectic 14-fluoromorphinans |
May. 29, 1984 |
| 4440931 |
7.beta.-Arylalkyl-3-methoxy or 3-hydroxy-4,5.alpha.-epoxy-6.beta.-hydroxy-7.alpha.-hydroxymethyl-17-met hyl or 17-cycloalkylmethylmorphinans |
Apr. 3, 1984 |
| 4440932 |
7.beta.-Arylalkyl-7.alpha.-methyl-6-oxo or 6.alpha.-hydroxy-3-methoxy or 3-hydroxy-4,5.alpha.-epoxy-17-methyl or 17-cycloalkyl-methylmorphinans |
Apr. 3, 1984 |
| 4390699 |
6-Keto-morphinans belonging to the 14-hydroxy-series |
Jun. 28, 1983 |
| 4388463 |
6-Keto-morphinan analgesics |
Jun. 14, 1983 |
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