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Class Information
Number: 546/45
Name: Organic compounds -- part of the class 532-570 series > Organic compounds (class 532, subclass 1) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., oxygen, sulfur, selenium, or tellurium) or nitrogen as the only ring hetero atoms (class 540, subclass 1) > Hetero ring is six-membered consisting of one nitrogen and five carbons > Polycyclo ring system having the six-membered hetero ring as one of the cyclos > Pentacyclo ring system having the six-membered hetero ring as one of the cyclos > Two of the cyclos share at least three ring members (i.e., bridged) > One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.) > Nitrogen or divalent chalcogen double bonded directly to carbocyclic ring of the pentacyclo ring system (e.g., morphinones, etc.)
Description: Compounds wherein a nitrogen atom or a divalent chalcogen (i.e., oxygen, sulfur, selenium, or tellurium) is attached directly by a double bond to a carbocyclic ring of the pentacyclo ring system.

Patents under this class:
1 2 3 4

Patent Number Title Of Patent Date Issued
8703949 Tandem process for preparing N-alkyl morphinans Apr. 22, 2014
8703950 Low ABUK oxycodone, its salts and methods of making same Apr. 22, 2014
8685995 Treatment with opioid antagonists and mTOR inhibitors Apr. 1, 2014
8669366 Process for the preparation of quaternary N-alkyl morphinan alkaloid salts Mar. 11, 2014
8653065 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder Feb. 18, 2014
8653271 Enhancing transdermal delivery of opioid antagonists and agonists using codrugs linked to bupropion or hydroxybupropion Feb. 18, 2014
8624031 Production of alkaloids without the isolation of intermediates Jan. 7, 2014
8623888 3-oxy-hydromorphone derivatives Jan. 7, 2014
8624030 N-demethylation of 6-keto morphinans Jan. 7, 2014
8598352 Preparation of nalmefene hydrochloride from naltrexone Dec. 3, 2013
8580963 Method for the manufacturing of naltrexone Nov. 12, 2013
8563726 Stereoselective reduction of a morphinone Oct. 22, 2013
8563571 Crystalline forms of oxymorphone hydrochloride Oct. 22, 2013
8563721 Morphinan derivatives and preparation methods thereof Oct. 22, 2013
8563725 Preparation of saturated ketone morphinan compounds having low metal content Oct. 22, 2013
8546572 Process for the preparation of morphinane analogues Oct. 1, 2013
8471022 Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone Jun. 25, 2013
8455509 Method for the preparation of morphine compounds Jun. 4, 2013
8455644 Peripheral opioid receptor antagonists and uses thereof Jun. 4, 2013
8445528 Dendrimer conjugates May. 21, 2013
8436175 Carboxamide bioisosteres of opiates May. 7, 2013
8436174 (+)-morphinanium quaternary salts and processes for their production May. 7, 2013
8399671 Methods for producing hydrocodone, hydromorphone or a derivative thereof Mar. 19, 2013
8399475 Crystalline and amorphous forms of naltrexone hydrochloride Mar. 19, 2013
8394813 Active agent delivery systems and methods for protecting and administering active agents Mar. 12, 2013
8383815 Heterogeneous ruthenium metal catalyst for the production of hydrocodone, hydromorphone or a derivative thereof Feb. 26, 2013
8367827 Process for preparing hydrocodone using a super acid Feb. 5, 2013
8357802 Process for preparing oxymorphone Jan. 22, 2013
8343992 Synthesis of R-N-methylnaltrexone Jan. 1, 2013
8318936 Method for producing N-methylnaltrexone bromide Nov. 27, 2012
8318937 Preparation of opiate analgesics by reductive alkylation Nov. 27, 2012
8314237 Preparation of 10-keto morphinans by benzylic oxidation Nov. 20, 2012
8309727 Opiate reduction utilizing catalytic hydrogen transfer reaction Nov. 13, 2012
8288547 N-methylnaltrexone zwitterion Oct. 16, 2012
8273888 Process for the preparation of 6-alpha-hydroxy-N-alkylated opiates Sep. 25, 2012
8269006 Processes for the selective amination of ketomorphinans Sep. 18, 2012
8252929 8-carboxamido-2,6-methano-3-benzazocines Aug. 28, 2012
8252834 Dendrimer conjugates Aug. 28, 2012
8252928 Processes for the synthesis of five and six membered heterocyclic rings Aug. 28, 2012
8236957 Process for making morphinan-6.alpha.-ols Aug. 7, 2012
8217175 Preparation of oxymorphone from oripavine Jul. 10, 2012
8183376 Stereoselective reduction of a morphinone May. 22, 2012
8168790 Process for the preparation of 6-beta hydroxy morphinan compounds May. 1, 2012
8158793 Demethylation of 14-hydroxy substituted alkaloid derivatives Apr. 17, 2012
8134002 Process for preparing oxymorphone Mar. 13, 2012
8119803 Preparation of opiate analgesics by reductive alkylation Feb. 21, 2012
8101756 Process for the preparation of quaternary N-alkyl morphin or morphinan alkaloid derivatives Jan. 24, 2012
8101757 Processes for the preparation of normorphinan salts Jan. 24, 2012
8067596 Processes for the production of (+)- "Nal" morphinan compounds Nov. 29, 2011
8067597 Synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs Nov. 29, 2011

1 2 3 4

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