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Class Information
Number: 546/44
Name: Organic compounds -- part of the class 532-570 series > Organic compounds (class 532, subclass 1) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., oxygen, sulfur, selenium, or tellurium) or nitrogen as the only ring hetero atoms (class 540, subclass 1) > Hetero ring is six-membered consisting of one nitrogen and five carbons > Polycyclo ring system having the six-membered hetero ring as one of the cyclos > Pentacyclo ring system having the six-membered hetero ring as one of the cyclos > Two of the cyclos share at least three ring members (i.e., bridged) > One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)
Description: Compounds wherein one of the cyclos of the pentacyclo ring system is a five-membered hetero ring which contains ring chalcogen (i.e., oxygen, sulfur, selenium, or tellurium).


Sub-classes under this class:

Class Number Class Name Patents
546/46 A single chalcogen is bonded directly to ring carbon of the pentacyclo ring system (e.g., desoxy morphine, etc.) 73
546/45 Nitrogen or divalent chalcogen double bonded directly to carbocyclic ring of the pentacyclo ring system (e.g., morphinones, etc.) 123


Patents under this class:
1 2 3 4

Patent Number Title Of Patent Date Issued
5240933 14-hydroxy-N-(2-methoxyethyl)-7,8-dihydromorphine and -norisomorphine, processes for the preparation thereof and the use thereof as pharmaceutical compositions Aug. 31, 1993
5241070 Nucleophilic polysubstituted aryl acridinium esters and uses thereof Aug. 31, 1993
5219861 6 .beta.-Thiomorphine derivatives Jun. 15, 1993
5208338 Radiolabeled N-substituted-6-iodo-3,14-dihydroxy-4,5.alpha.-epoxymorphinans May. 4, 1993
5190947 Codeine salt of a substituted carboxylic acid, its use and pharmaceutical compositions thereof Mar. 2, 1993
5112975 Preparation of noroxymorphone from morphine May. 12, 1992
5071985 Process for the preparation of morphinane derivatives Dec. 10, 1991
5001115 Prodrugs of biologically active hydroxyaromatic compounds Mar. 19, 1991
4990617 N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans and derivatives Feb. 5, 1991
4939264 Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies Jul. 3, 1990
4912114 Morphinan derivatives Mar. 27, 1990
4806556 Gut-selective opiates Feb. 21, 1989
4798792 Bacterial hydroxylation of codeine Jan. 17, 1989
4795813 Synthesis of derivatives of codeine and other 3-O-alkylmorphines Jan. 3, 1989
4775759 Synthesis and utilization of 17-methyl and 17-cyclopropylmethyl-3,14-dihydroxy-4,5.alpha.-epoxy 6.beta.-fluoromorphinans (foxy and cyclofoxy) as (18F)-labeled opioid ligands for position e Oct. 4, 1988
4767718 Fluorescent opioid reagents and methods of use thereof in the detection of opioid receptors Aug. 30, 1988
4764615 Process for the preparation of codeine from morphine Aug. 16, 1988
4751306 Imide intermediates for the preparation of analgesic and/or antagonist octahydrobenzofuroisoquinolines Jun. 14, 1988
4751307 Wittig-reaction processes Jun. 14, 1988
4749706 Orally active nonaddicting analgesics Jun. 7, 1988
4730048 Gut-selective opiates Mar. 8, 1988
4727146 Synthesis of chiral 1-benzyl-1,2,3,4-tetra-hydroisoquinolines by asymmetric reduction Feb. 23, 1988
4718215 Apparatus and method for attaching fitments to flexible containers Jan. 12, 1988
4678779 Weight control method Jul. 7, 1987
4673679 Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration Jun. 16, 1987
4668685 Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists May. 26, 1987
4667037 Dealkylation of opioid ethers May. 19, 1987
4639520 Preparation of 14-hydroxy-N-ethoxy-carbonyl-norcodeinone Jan. 27, 1987
4613668 Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl Sep. 23, 1986
4599341 Substituted and bridged pyridines useful as calcium channel blockers Jul. 8, 1986
4587253 Bridged pyridine compounds useful as calcium channel blockers and analgesics May. 6, 1986
4556712 Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines Dec. 3, 1985
4535157 Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone Aug. 13, 1985
4521601 Practical total synthesis unnatural enantiomers of opium-derived morphinans Jun. 4, 1985
4514569 Synthesis of 1-substituted isoquinolines Apr. 30, 1985
4477456 Octahydro-4A,7-ethano- and -etheno-benzofuro[3,2-e]isoquinoline derivatives having analgesic, narcotic antagonist and anorexigenic properties Oct. 16, 1984
4464378 Method of administering narcotic antagonists and analgesics and novel dosage forms containing same Aug. 7, 1984
4451470 Analgesic, antagonist, and/or anorectic 14-fluoromorphinans May. 29, 1984
4443605 7.beta.-Arylalkyl-6.alpha., 7 .alpha.-oxymethylene-3-methoxy or 3-hydroxy-4, 5.alpha.-epoxy-17 methyl or 17-cycloalkyl-methyl morphinans Apr. 17, 1984
4440932 7.beta.-Arylalkyl-7.alpha.-methyl-6-oxo or 6.alpha.-hydroxy-3-methoxy or 3-hydroxy-4,5.alpha.-epoxy-17-methyl or 17-cycloalkyl-methylmorphinans Apr. 3, 1984
4440931 7.beta.-Arylalkyl-3-methoxy or 3-hydroxy-4,5.alpha.-epoxy-6.beta.-hydroxy-7.alpha.-hydroxymethyl-17-met hyl or 17-cycloalkylmethylmorphinans Apr. 3, 1984
4410700 Preparation of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines by optical resolution Oct. 18, 1983
4362870 Selective opioid receptor alkylating agents Dec. 7, 1982
4322426 17-Substituted-6-desoxy-7,8-dihydro-6.alpha.-methylnoroxymorphone narcotic antagonists Mar. 30, 1982
4296238 2,6-Methano-3-benzazocines Oct. 20, 1981
4277604 Facile synthesis of codeine precursors from thebaine Jul. 7, 1981
4275205 7,7-Ditosyloxymethyl-4,5.alpha.-epoxy-morphinan-6-ols Jun. 23, 1981
4269843 N-Sec-alkyl analogs of norcodeine and normorphine and analgesic compositions and methods employing the normorphine derivatives May. 26, 1981
4255329 Double receptor fluorescent immunoassay Mar. 10, 1981
4255579 11-Substituted hexahydro-2,6-methano-3-benzazocines Mar. 10, 1981

1 2 3 4


 
 
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