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Class Information
Number: 544/260
Name: Organic compounds -- part of the class 532-570 series > Organic compounds (class 532, subclass 1) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., oxygen, sulfur, selenium, or tellurium) or nitrogen as the only ring hetero atoms (class 540, subclass 1) > Hetero ring is six-membered having two or more ring hetero atoms of which at least one is nitrogen (e.g., selenazines, etc.) > The six-membered hetero ring consists of two nitrogens and four carbons (e.g., 1,2-diazines, etc.) > 1,3-diazines > Polycyclo ring system having the diazine ring as one of the cyclos > Bicyclo ring system having the diazine ring as one of the cyclos > Four ring hetero atoms in the bicyclo ring system > Four ring nitrogens in the bicyclo ring system > Pteridines (including hydrogenated) > Nitrogen bonded directly to the pteridine ring system > Plural nitrogens bonded directly to the pteridine ring system > At 2- and 4-positions
Description: Compounds wherein nitrogen atoms are bonded directly to the 2- and 4-position carbons of the pteridine ring system.
Patents under this class:
| Patent Number |
Title Of Patent |
Date Issued |
| 7351827 |
Substituted oxetanes, method of making, and method of use thereof |
Apr. 1, 2008 |
| 7241889 |
6-formyl-tetrahydropteridines, process for their manufacture and use thereof as medicaments |
Jul. 10, 2007 |
| 7235660 |
Facile process for the preparation of high-purity aminopterin |
Jun. 26, 2007 |
| 7230101 |
Synthesis of methotrexate-containing heterodimeric molecules |
Jun. 12, 2007 |
| 7169778 |
Pteridinones as kinase inhibitors |
Jan. 30, 2007 |
| 6989386 |
Pharmaceutically active ornithine derivatives, ammonium salts thereof and methods of making same |
Jan. 24, 2006 |
| 6906070 |
Guanidine mimics as factor Xa inhibitors |
Jun. 14, 2005 |
| 6858612 |
Use of tetrahydropteridine derivatives as no synthase inhibitors |
Feb. 22, 2005 |
| 6844343 |
N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent |
Jan. 18, 2005 |
| 6720304 |
Conjugate comprising a folic acid antagonist and a carrier |
Apr. 13, 2004 |
| 6559149 |
Methotrexate derivatives |
May. 6, 2003 |
| 6399609 |
Therapeutic usage of tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders |
Jun. 4, 2002 |
| 6291673 |
Folic acid derivatives |
Sep. 18, 2001 |
| 6143744 |
Sulfamide-metalloprotease inhibitors |
Nov. 7, 2000 |
| 6130101 |
Sulfonated xanthene derivatives |
Oct. 10, 2000 |
| 6083948 |
Tetrahydropteridines for treatment of neurological disorders |
Jul. 4, 2000 |
| 6028071 |
Purified compositions of 10-propargyl-10-deazaaminopterin and methods of using same in the treatment of tumors |
Feb. 22, 2000 |
| 6011181 |
Triphenylphosphine oxide complex process |
Jan. 4, 2000 |
| 5952499 |
Therapeutic compound-fatty acid conjugates |
Sep. 14, 1999 |
| 5922713 |
Inhibition of nitric oxide synthase |
Jul. 13, 1999 |
| 5910588 |
Crystal modification of 2,4-diamino-6-hydroxymethylpteridine hydrobromide |
Jun. 8, 1999 |
| 5902810 |
Pteridine derivatives as no synthase inhibitors |
May. 11, 1999 |
| 5874433 |
Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis |
Feb. 23, 1999 |
| 5869665 |
Quinazolinone derivatives as cholecystokinin (CCK) ligands |
Feb. 9, 1999 |
| 5807854 |
Pyrimidone derivatives with antifungal activity |
Sep. 15, 1998 |
| 5760229 |
Crystal modification of 2,4-diamino-6-hydroxymethylpteridine hydrobromide |
Jun. 2, 1998 |
| 5698556 |
Methotrexate analogs and methods of using same |
Dec. 16, 1997 |
| 5693641 |
Bicyclic pyrimidine derivatives and their use as anti-coagulants |
Dec. 2, 1997 |
| 5593671 |
Method of attenuating lung capillary leak in a mammal |
Jan. 14, 1997 |
| 5550128 |
Enantiomers of gamma methylene 10-deaza aminopterin and process for preparing the same |
Aug. 27, 1996 |
| 5532367 |
Insecticidal pteridines and 8-deazapteridines |
Jul. 2, 1996 |
| 5521190 |
Insecticidal pterdines and 8-deazapteridines |
May. 28, 1996 |
| 5382582 |
Methotrexate analogs and methods of using same |
Jan. 17, 1995 |
| 5374726 |
Process for preparing 10-deazaaminopterins and 5,10-and 8,10-dideazaaminopterins from pteroic dicarboxylic acid diesters |
Dec. 20, 1994 |
| 5354753 |
Methotrexate derivative |
Oct. 11, 1994 |
| 5354751 |
Heteroaroyl 10-deazaamino-pterine compounds and use for rheumatoid arthritis |
Oct. 11, 1994 |
| 5350850 |
Process for the preparation of substituted tetrahydrofolico derivatives in the [6(R,S)(-)] forms and of their active [6(S)(-)] N.sup.5 diastereoisomers in form of alkali and alkaline earth met |
Sep. 27, 1994 |
| 5286726 |
Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases |
Feb. 15, 1994 |
| 5260296 |
Thiophene substituted antitumor antifolates |
Nov. 9, 1993 |
| 5198547 |
Process for N5-formylating tetrahydropteridines |
Mar. 30, 1993 |
| 5196533 |
Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines |
Mar. 23, 1993 |
| 5167963 |
8,10-dideazatetrahydrofolic acid derivatives |
Dec. 1, 1992 |
| 5141941 |
Aralkylamine derivatives, and fungicides containing the same |
Aug. 25, 1992 |
| 5140104 |
Amine derivatives of folic acid analogs |
Aug. 18, 1992 |
| 5103007 |
Lipids |
Apr. 7, 1992 |
| 5081245 |
Carboxylic acid derivatives |
Jan. 14, 1992 |
| 5077404 |
Cyclized 5,10-dideazaaminopterin compounds |
Dec. 31, 1991 |
| 5073554 |
Two non-polyglutamatable antifolates |
Dec. 17, 1991 |
| 5028697 |
Cytotoxic antibody conjugates of hydrazide derivatized methotrexate analogs via simple organic linkers |
Jul. 2, 1991 |
| 4996207 |
Three new non-polyglutamatable deazaaminopterins |
Feb. 26, 1991 |
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