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Class Information
Number: 514/307
Name: Drug, bio-affecting and body treating compositions > Designated organic active ingredient containing (doai) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., o,s,se or te) or nitrogen as the only ring hetero atoms doai > Hetero ring is six-membered consisting of one nitrogen and five carbon atoms > Polycyclo ring system having the six-membered hetero ring as one of the cyclos > Bicyclo ring system having the six-membered hetero ring as one of the cyclos > Isoquinolines (including hydrogenated)

Sub-classes under this class:

Class Number Class Name Patents
514/309 Chalcogen attached directly to the six-membered hetero ring by nonionic bonding 553
514/310 Nitrogen, other than as nitro or nitroso, attached directly to the isoquinoline ring system by nonionic bonding 466
514/308 Plural isoquinoline ring systems attached directly or indirectly to each other by nonionic bonding 118

Patents under this class:

Patent Number Title Of Patent Date Issued
8710076 2,5-disubstituted piperidine orexin receptor antagonists Apr. 29, 2014
8710043 TRPM8 antagonists and their use in treatments Apr. 29, 2014
8685960 6-pyridin-3-yl-3,4-dihydro-1h-quinolin-2-one derivatives and related compounds as inhibitors of the human aldosterone synthase CYP11B2 Apr. 1, 2014
8669272 2,5-disubstituted piperidine orexin receptor antagonists Mar. 11, 2014
8664245 Fumarate salts of a histamine H3 receptor antagonist Mar. 4, 2014
8664243 Sulfonamide compound and crystal thereof Mar. 4, 2014
8653100 Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy Feb. 18, 2014
8653099 Cold menthol receptor antagonists Feb. 18, 2014
8637496 Compounds having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions Jan. 28, 2014
8633182 Indanyloxyphenylcyclopropanecarboxylic acids Jan. 21, 2014
8623892 Metalloenzyme inhibitor compounds Jan. 7, 2014
8623891 Methods for treating cognitive disorders using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds Jan. 7, 2014
8623889 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof Jan. 7, 2014
8623877 Substituted N-heteroaryl tetrahydro-isoquinoline derivatives, preparation and therapeutic use thereof Jan. 7, 2014
8614227 Salt and solvates of a tetrahydroisoquinoline derivative Dec. 24, 2013
8598217 Imidazole derivatives and their use as modulators of cyclin dependent kinases Dec. 3, 2013
8592450 Compositions and methods for treatment of eye disorders Nov. 26, 2013
8586570 Sox-based kinase sensor Nov. 19, 2013
8586565 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases Nov. 19, 2013
8575193 N-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds Nov. 5, 2013
8569339 Soluble guanylate cyclase activators Oct. 29, 2013
8563578 Antitumor properties of NO modified protease inhibitors Oct. 22, 2013
8557812 Small molecule inhibitors of anti-apoptotic BCL-2 family members and the uses thereof Oct. 15, 2013
8552028 8-phenylisoquinolines and pharmaceutical composition used in treatment for sepsis Oct. 8, 2013
8551992 Aminooxazole inhibitors of cyclin dependent kinases Oct. 8, 2013
8541448 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders Sep. 24, 2013
8541404 Inhibitors of the human aldosterone synthase CYP11B2 Sep. 24, 2013
8524700 Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics Sep. 3, 2013
8507523 Therapeutic tetrahydroisoquinoline-based compositions for cancer therapy Aug. 13, 2013
8501736 Isoquinoline derivatives Aug. 6, 2013
8481532 PDE-10 inhibitors Jul. 9, 2013
8476298 c-Met modulators and method of use Jul. 2, 2013
8476297 TRP-M8 receptor ligands and their use in treatments Jul. 2, 2013
8470813 Thiazoline and oxazoline derivatives and their methods of use Jun. 25, 2013
8466172 Stabilization of hypoxia inducible factor (HIF) alpha Jun. 18, 2013
8455515 Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, pharmaceutical compositions and therapeutic use Jun. 4, 2013
8455514 6-and 7-amino isoquinoline compounds and methods for making and using the same Jun. 4, 2013
8455513 6-aminoisoquinoline compounds Jun. 4, 2013
8440691 Tetrahydroquinolinyl compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor and uses thereof May. 14, 2013
8415372 Sulfonamide compound Apr. 9, 2013
8404686 Method of treatment or prophylaxis Mar. 26, 2013
8399482 6-substituted isoquinolines and isoquinolinones Mar. 19, 2013
8399465 Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene A.sub.4 hydrolase Mar. 19, 2013
8399435 Compounds for the treatment of proliferative disorders Mar. 19, 2013
8394826 Dual mechanism inhibitors for the treatment of disease Mar. 12, 2013
8394825 Compound Mar. 12, 2013
8389543 Metalloenzyme inhibitor compounds Mar. 5, 2013
8383094 Hepatitis C virus inhibitors Feb. 26, 2013
8367701 Crystalline pharmaceutical and methods of preparation and use thereof Feb. 5, 2013
8367700 Substituted 4-(1.2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutyric acid amide as KCNQ2/3 modulators Feb. 5, 2013

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