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Class Information
Number: 514/265.1
Name: Drug, bio-affecting and body treating compositions > Designated organic active ingredient containing (doai) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., o,s,se or te) or nitrogen as the only ring hetero atoms doai > Hetero ring is six-membered consisting of two nitrogens and four carbon atoms (e.g., pyridazines, etc.) > 1,3-diazines (e.g., pyrimidines, etc.) > Polycyclo ring system having 1,3-diazine as one of the cyclos > Bicyclo ring system having the 1,3-diazine as one of the cyclos > The other cyclo in the bicyclo ring system is a pyrrole ring (including hydrogenated) (e.g., pyrrolo[3,2-d]pyrimidine, etc.)
Description: Subject matter wherein the second ring of the bicyclo ring system containing the 1,3-diazine ring is five-membered consisting of one nitrogen and four carbons, including hydrogenated compounds thereof.

Patents under this class:
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Patent Number Title Of Patent Date Issued
8710043 TRPM8 antagonists and their use in treatments Apr. 29, 2014
8691810 Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases Apr. 8, 2014
8691830 CDK inhibitors Apr. 8, 2014
8685980 Pyrrolopyrimidine compounds and their uses Apr. 1, 2014
8685983 Method of treating cancer with substituted amide derivatives Apr. 1, 2014
8685988 EGFR modulators and uses thereof Apr. 1, 2014
8673928 Compounds and methods for kinase modulation, and indications therefor Mar. 18, 2014
8658637 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof Feb. 25, 2014
8658635 Benzpyrazol derivatives as inhibitors of PI3 kinases Feb. 25, 2014
8648086 5,6-bicyclic heteroaryl-containing urea compounds as kinase inhibitors Feb. 11, 2014
8642604 Substituted pyrazolo[3,2-d]pyrimidines as anti-cancer agents Feb. 4, 2014
8633193 Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds Jan. 21, 2014
8633205 Substituted pyrrolo[2,3-d]pyrimidines as inhibitors of protein kinases Jan. 21, 2014
8633206 Pyrrolo[2,3-D]pyrimidine compounds Jan. 21, 2014
8629152 Processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid Jan. 14, 2014
8609647 Nitrogen-containing spirocyclic compounds and pharmaceutical uses thereof Dec. 17, 2013
8609690 Aryl- and heteroarylcarbonyl derivatives of substituted nortropanes, medicaments containing such compounds and their use Dec. 17, 2013
8604032 Chemical compounds, compositions and methods for kinase modulation Dec. 10, 2013
8604043 3-[4-(7H-pyrrolo[2,3-D]pyrimidin-4-yl)-1H-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors Dec. 10, 2013
8598156 Chemical compounds Dec. 3, 2013
8598186 CDK inhibitors Dec. 3, 2013
8592433 Compounds and compositions as protein kinase inhibitors Nov. 26, 2013
8592432 Compounds and compositions as protein kinase inhibitors Nov. 26, 2013
8586505 4-(3-butynyl)aminopyrimidine derivatives as pest control agents for agricultural and horticultural use Nov. 19, 2013
8586596 Compounds as cannabinoid receptor ligands Nov. 19, 2013
8586633 Ophthalmologic irrigation solutions and method Nov. 19, 2013
8580803 Substituted pyrrolo-aminopyrimidine compounds Nov. 12, 2013
8580802 Pyrrolo[2,3-D]pyrimidines as inhibitors of Janus kinases Nov. 12, 2013
8575183 Heterocyclic compounds and their uses Nov. 5, 2013
8563570 Lactam compounds and their use as pharmaceuticals Oct. 22, 2013
8551965 Anti-viral pyrimidine nucleoside analogues Oct. 8, 2013
8552014 Methods of using selective chemotherapeutic agents for targeting tumor cells Oct. 8, 2013
8546408 Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation Oct. 1, 2013
8546407 Ortho-condensed pyridine and pyrimidine derivatives (e.g., purines) as protein kinases inhibitors Oct. 1, 2013
8541425 Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors Sep. 24, 2013
8541426 Pharmaceutical compositions and methods of treating dry eye disorders Sep. 24, 2013
8541427 Phenyl-substituted 2-imino-3-methyl pyrrolo pyrimidinone compounds as BACE-1 inhibitors, compositions, and their use Sep. 24, 2013
8530485 Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors Sep. 10, 2013
8524710 Pyrrolidine derivatives Sep. 3, 2013
8524712 Triazinone and diazinone derivatives useful as HSP90 inhibitors Sep. 3, 2013
8524720 Substituted N-(pyrazol-5-yl)-pyrrolo[3,2-D]pyrimidin-4-amine useful as protein kinase inhibitors Sep. 3, 2013
8507508 Solid forms of pemetrexed Aug. 13, 2013
8501753 Useful pharmaceutical salts of 7-[(3R, 4R)-3-Hydroxy-4-hydroxymethyl-pyrrolidin-1-ylmethyl]-3, 5-dihydro-pyrrolo [3, 2-D] pyrimidin-4-one Aug. 6, 2013
8501752 Methods for treating cancer and other pathological proliferating disorders by inhibiting mitosis using pyrrolo[2,3-d]pyrimidines Aug. 6, 2013
8486902 Hydroxyl, keto, and glucuronide derivatives of 3-(4-(7H-pyrrolo[2,3-d] pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile Jul. 16, 2013
8481550 Heteroaryl compounds useful as inhibitors of E1 activating enzymes Jul. 9, 2013
8476282 Benzoxazole kinase inhibitors and methods of use Jul. 2, 2013
8470850 Inhibitors of VEGF receptor and HGF receptor signalling Jun. 25, 2013
8461165 2-Substituted phenyl-5,7-dihydrocarbyl-3,7-dihydropyrrolo[2,3-d] pyrimidin-4-one derivatives, the preparation and the pharmaceutical use thereof Jun. 11, 2013
8455505 Pyrrolopyrimidinedione and its therapeutic use Jun. 4, 2013

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