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Class Information
Number: 514/255.06
Name: Drug, bio-affecting and body treating compositions > Designated organic active ingredient containing (doai) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., o,s,se or te) or nitrogen as the only ring hetero atoms doai > Hetero ring is six-membered consisting of two nitrogens and four carbon atoms (e.g., pyridazines, etc.) > 1,4 diazines > Nitrogen or -c(=x)-, wherein x is chalcogen, bonded directly to ring carbon of the 1,4-diazine ring
Description: Subject matter wherein a ring carbon of the 1,4-diazine ring is bonded directly to a nitrogen atom or a -C(=X)- group, wherein X is chalcogen (i.e., oxygen, sulfur, selenium, or tellurium).










Patents under this class:
1 2 3 4 5 6 7 8

Patent Number Title Of Patent Date Issued
8703100 Modified pyrazine derivatives and uses thereof Apr. 22, 2014
8686048 Immunomodulator and anti-inflammatory compounds Apr. 1, 2014
8680100 Sulfonylhydrazide compounds for treating proliferative disorders Mar. 25, 2014
8673964 Use of drug combinations for treating insulin resistance Mar. 18, 2014
8669262 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amin- o)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide Mar. 11, 2014
8664228 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid derivatives and their use as epithelial sodium channel blockers for the treatment of airway diseases Mar. 4, 2014
8653086 Naphthamides as anticancer agents Feb. 18, 2014
8628751 Pyrazine derivatives for optical imaging and therapy Jan. 14, 2014
8614213 Cyclohexyl amide derivatives and their use as CRF-1 receptor antagonists Dec. 24, 2013
8575175 Therapeutic agent for chronic renal failure Nov. 5, 2013
8575176 Heteroaromatic pyrazinoylguanidine sodium channel blockers Nov. 5, 2013
8518450 Nanoparticle carriers for drug administration and process for producing same Aug. 27, 2013
8518950 2-amido pyrazines for inflammation and immune related uses Aug. 27, 2013
8513261 Tablet and granulated powder containing 6-fluoro-3-hydroxy-2-pyrazinecarboxamide Aug. 20, 2013
8507497 Capped pyrazinoylguanidine sodium channel blockers Aug. 13, 2013
8476269 Pyridine and pyrazine derivative for the treatment of CF Jul. 2, 2013
8461161 Substituted pyrazines as inhibitors of kinase activity Jun. 11, 2013
8431579 Capped pyrazinoylguanidine sodium channel blockers Apr. 30, 2013
8415360 Pharmaceutical compositions for the treatment of diabetes mellitus Apr. 9, 2013
8410114 2-pyrazinone derivatives for the treatment of disease or condition in which inhibition of neutrophil elastase activity is beneficial Apr. 2, 2013
8410112 Compounds useful as inhibitors of ATR kinase Apr. 2, 2013
8394806 2-phenyl pyrazines as tubulin inhibitors Mar. 12, 2013
8383653 SIR2 regulation Feb. 26, 2013
8372845 Pyrazine derivatives as enac blockers Feb. 12, 2013
8372846 Co-crystals and pharmaceutical compositions comprising the same Feb. 12, 2013
8372847 Pyrazinone modulator of corticotropin-releasing factor receptor activity Feb. 12, 2013
8367673 Substituted diketopiperazines as oxytocin antagonists Feb. 5, 2013
8357685 Substituted diketopiperazines and their use as oxytocin antagonists Jan. 22, 2013
8329707 Substituted pyrazine compounds Dec. 11, 2012
8324218 Aliphatic pyrazinoylguanidine sodium channel blockers with beta agonist activity Dec. 4, 2012
8324219 Substituted benzoimidazolyl-pyrazine compounds for inflammation and immune-related uses Dec. 4, 2012
8318723 Pyrazine compounds, their use and methods of preparation Nov. 27, 2012
8314108 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-ylamino)pyrazine-2-- carbonitrile, pharmaceutically acceptable salts thereof, or solvate of salts Nov. 20, 2012
8309608 Use of eNOS transcription enhancers in the cell therapy of ischemic heart diseases Nov. 13, 2012
8288391 Pyrazinoylguanidine compounds for use as taste modulators Oct. 16, 2012
8268834 Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme Sep. 18, 2012
8263578 Stable bortezomib formulations Sep. 11, 2012
8236808 Pyrazine derivatives as ENAC blockers Aug. 7, 2012
8217048 Inhibitors of serine proteases, particularly HCV NS3-NS4A protease Jul. 10, 2012
8211895 Capped pyrazinoylguanidine sodium channel blockers Jul. 3, 2012
8198286 Sodium channel blockers Jun. 12, 2012
8188092 Substituted pyrazines as DGAT-1 inhibitors May. 29, 2012
8188093 Pyrazinecarboxamide derivatives as HDL-cholesterol raising agents May. 29, 2012
8163758 Phenyl substituted pyrazinoylguanidine sodium channel blockers possessing beta agonist activity Apr. 24, 2012
8143256 Cyclic amide and ester pyrazinoylguanidine sodium channel blockers Mar. 27, 2012
8124607 Poly aromatic pyrazinoylguanidine sodium channel blockers Feb. 28, 2012
8114881 2-pyrazinone derivatives for the treatment of disease or condition in which inhibition of neutrophil elastase activity is beneficial Feb. 14, 2012
8114871 3-amido-pyrrolo[3,4-C]pyrazole-5(1H,4H,6H) carbaldehyde derivatives Feb. 14, 2012
8110579 5,6-bisaryl-2-pyridine-carboxamide derivatives, preparation and application thereof in therapeutics as urotensin II receptor antagonists Feb. 7, 2012
8093252 Crystalline polymorphic form of glucokinase activator Jan. 10, 2012

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