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Class Information
Number: 514/252.15
Name: Drug, bio-affecting and body treating compositions > Designated organic active ingredient containing (doai) > Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., o,s,se or te) or nitrogen as the only ring hetero atoms doai > Hetero ring is six-membered consisting of two nitrogens and four carbon atoms (e.g., pyridazines, etc.) > 1,4 diazines > Piperazines (i.e., fully hydrogenated 1,4-diazines) > Additional hetero ring attached directly or indirectly to the piperazine ring by nonionic bonding > The additional hetero ring is a 1,3 diazine ring > Spiro ring system containing
Description: Subject matter wherein the active ingredient containing the diazine rings includes a spiro ring system.










Patents under this class:
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Patent Number Title Of Patent Date Issued
8618097 Pyrimidyl cyclopentanes as AKT protein kinase inhibitors Dec. 31, 2013
8557796 Substituted 1-oxa-2,8-diaza-spiro [4,5] dec-2-ene derivatives and related treatment methods Oct. 15, 2013
8445482 Thieno- and furo-pyrimidine modulators of the histamine H.sub.4 receptor May. 21, 2013
8440654 Thieno- and furo-pyrimidine modulators of the histamine H4 receptor May. 14, 2013
8193178 Thieno- and furo-pyrimidine modulators of the histamine H.sub.4 receptor Jun. 5, 2012
8039472 Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel Oct. 18, 2011
7704996 Compounds and compositions useful as cathepsin S inhibitors Apr. 27, 2010
7482346 Derivatives of alkylpiperazine and alkylhomopiperazine-carboxylates, preparation method thereof and use of same as fatty acid amido hydrolase enzyme inhibitors Jan. 27, 2009
7452886 Pyrrolo pyrimidines as agents for the inhibition of cystein proteases Nov. 18, 2008
7238693 Aryl carbamate derivatives, preparation and use thereof Jul. 3, 2007
7214676 Spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors May. 8, 2007
7071194 Method for improving respiratory function and inhibiting muscular degeneration Jul. 4, 2006
6821976 S-6-hydroxy-buspirone Nov. 23, 2004
6803368 Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene Oct. 12, 2004
6743798 Substituted pyrazole derivatives condensed with six-membered heterocyclic rings Jun. 1, 2004
6686361 R-6-hydroxy-buspirone Feb. 3, 2004
6649614 Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent for treatment of depression or anxiety Nov. 18, 2003
6617329 Aminoquinazolines and their use as medicaments Sep. 9, 2003
6579899 Composition for treatment of stress Jun. 17, 2003
6566361 Azapirone pain treatment May. 20, 2003
6541478 Smoking cessation treatments using naltrexone and related compounds Apr. 1, 2003
6511982 Treatment of pain Jan. 28, 2003
6268368 Anionic exchange polymer complexes of buspirone Jul. 31, 2001
6242447 Surgical irrigation solution and method for inhibition of pain and inflammation Jun. 5, 2001
6218395 Centrally-acting beta-blockers and serotonin-enhancers for the treatment of anxiety disorders and adjustment disorders with anxiety Apr. 17, 2001
6150365 Anxiety method Nov. 21, 2000
6022869 Aminoheterocyclic compounds with antithrombotic/anticoagulant effect Feb. 8, 2000
6013644 Spiro-substituted azacycles as modulators of chemokine receptor activity Jan. 11, 2000
6008222 Method for oral administration of buspirone and nefazodone Dec. 28, 1999
5955459 Fatty acid-antipsychotic compositions and uses thereof Sep. 21, 1999
5861399 Methods and compositions for the rapid and enduring relief of inadequate myocardial function Jan. 19, 1999
5837280 Transdermal administration of azapirones Nov. 17, 1998
5817331 Transdermal administration of azapirones Oct. 6, 1998
5633009 Transdermal administration of azapirones May. 27, 1997
5521183 Use of 5-HT ligands as anti-pruritic agents May. 28, 1996
5468749 Method for treatment of substance addiction Nov. 21, 1995
5461054 Anthracene-spiro-pyrrolindines Oct. 24, 1995
5444082 3,9-disubstituted-spiro(5.5)undecanes active on the cardiovascular system, process for their preparation and pharmaceutical composition containing same Aug. 22, 1995
5417987 Method for controlling bivalves such as zebra mussels May. 23, 1995
5371087 3-<4-substituted-4-piperazinyl)buty]-4-thiazolidinone and related compounds Dec. 6, 1994
5314888 Veterinary method for treating inappropriate elimination of urine in household pets May. 24, 1994
5258379 Method of inhibiting gastric acid secretion with n-arylpiperazines Nov. 2, 1993
5229388 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds Jul. 20, 1993
5194436 1-piperazinyl-2-butenes and -2-butynes Mar. 16, 1993
5185329 Method for treatment of substance addiction Feb. 9, 1993
5098889 Method for preventing or inhibiting loss of cognitive function employing a combination of an ace inhibitor and a drug that acts at serotonin receptors Mar. 24, 1992
5043327 Positive inotropic and lusitropic 3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one derivatives, compositions and use Aug. 27, 1991
5032578 Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors Jul. 16, 1991
5015646 Pharmaceutically useful polymorphic modification of buspirone May. 14, 1991
4994455 Anti-anxiety agents Feb. 19, 1991

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