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Class Information
Number: 435/DIG.1
Name: Chemistry: molecular biology and microbiology > Combinatorial chemistry and library technology

Sub-classes under this class:

Class Number Class Name Patents
435/DIG.43 Apparatus 22
435/DIG.22 Library or combinatorial chemistry related product 30
435/DIG.46 Method of making a library 32
435/DIG.2 Method of screening a library 59

Patents under this class:
1 2

Patent Number Title Of Patent Date Issued
RE39571 Methods and apparatus for synthesizing labeled combinatorial chemistry libraries Apr. 17, 2007
7184893 Method for selecting an optimally diverse library of small molecules based on validated molecular structural descriptors Feb. 27, 2007
7122321 High throughput method for functionally classifying proteins identified using a genomics approach Oct. 17, 2006
7105290 Use of a BMP protein receptor complex for screening bone metabolism actives and cells co-transfected with a type II BMP receptor and a type I BMP receptor Sep. 12, 2006
7083917 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays Aug. 1, 2006
7083914 Color-encoding and in-situ interrogation of matrix-coupled chemical compounds Aug. 1, 2006
7067251 Methods of directly selecting cells expressing inserts of interest Jun. 27, 2006
7067252 Method for genome mining for secreted protein genes Jun. 27, 2006
7067326 Synthetic receptors, libraries and uses thereof Jun. 27, 2006
7060433 Methods and compositions for screening using diphtheria toxin constructs Jun. 13, 2006
7033748 Identification of microbial polynucleotides expressed during infection of a host Apr. 25, 2006
7029842 Signal sequence trapping Apr. 18, 2006
7029847 Methods and compositions for interaction trap assays Apr. 18, 2006
7026166 Fluorogenic dyes Apr. 11, 2006
7026114 Methods and compositions for monitoring polymer array synthesis Apr. 11, 2006
7022980 Spectral axis transform Apr. 4, 2006
6936471 Instrument for high throughput measurement of material physical properties and method of using same Aug. 30, 2005
6936477 Complex combinatorial chemical libraries encoded with tags Aug. 30, 2005
6916605 Methods for producing members of specific binding pairs Jul. 12, 2005
6897017 Vivo library-versus-library selection of optimized protein-protein interactions May. 24, 2005
6878557 Logically ordered arrays of compounds and methods of making and using the same Apr. 12, 2005
6861220 Genetic screening methods Mar. 1, 2005
6858383 Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor Feb. 22, 2005
6830890 Nucleic acid probe libraries Dec. 14, 2004
6828435 Combinatorial protecting group strategy for multifunctional molecules Dec. 7, 2004
6808876 Cellular regulators of infectious agents and methods of use Oct. 26, 2004
6806079 Methods for producing members of specific binding pairs Oct. 19, 2004
6794128 Methods of selecting internalizing antibodies Sep. 21, 2004
6767701 Methods of constructing and screening a DNA library of interest in filamentous fungal cells Jul. 27, 2004
6682888 Genes expressed in alzheimer's disease Jan. 27, 2004
6680202 Method for concurrent and sequential multi-step reactions for producing a plurality of different chemical compounds Jan. 20, 2004
6599697 Process for preparing a multicombinatorial library of vectors for expressing antibody genes Jul. 29, 2003
6593081 Production of anti-self antibodies from antibody segment repertoires and displayed on phage Jul. 15, 2003
6589730 Methods for identifying protein-protein interactions by selective transduction Jul. 8, 2003
6582915 Production of anti-self bodies from antibody segment repertories and displayed on phage Jun. 24, 2003
6569623 Genetic screening methods May. 27, 2003
6569631 Microplate thermal shift assay for ligand development using 5-(4"dimethylaminophenyl)-2-(4'-phenyl)oxazole derivative fluorescent dyes May. 27, 2003
6555313 Production of anti-self antibodies from antibody segment repertoires and displayed on phage Apr. 29, 2003
6544731 Production of anti-self antibodies from antibody segment repertories and displayed on phage Apr. 8, 2003
6521404 Production of anti-self antibodies from antibody segment repertoires and displayed on phage Feb. 18, 2003
6509454 Free solution ligand interaction molecular separation method Jan. 21, 2003
6506558 Very large scale immobilized polymer synthesis Jan. 14, 2003
6503759 Complex combinatorial chemical libraries encoded with tags Jan. 7, 2003
6500617 Optimization of pest resistance genes using DNA shuffling Dec. 31, 2002
6492125 Method to assess library X library interactions Dec. 10, 2002
6475807 Mass-based encoding and qualitative analysis of combinatorial libraries Nov. 5, 2002
6472150 Sifter screening to identify biologically active molecules Oct. 29, 2002
6472146 Methods for identification on internalizing ligands and identification of known and putative ligands Oct. 29, 2002
6468806 Potential masking systems and methods for combinatorial library synthesis Oct. 22, 2002
6440669 Methods for applying small volumes of reagents Aug. 27, 2002

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