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Class Information
Number: 435/69.2
Name: Chemistry: molecular biology and microbiology > Micro-organism, tissue cell culture or enzyme using process to synthesize a desired chemical compound or composition > Recombinant dna technique included in method of making a protein or polypeptide > Enzyme inhibitors or activators
Description: Processes under subclasses 69.1 wherein the product synthesized is an enzyme inhibitor or activator which is a protein or polypeptide.










Patents under this class:
1 2 3 4 5 6 7 8 9 10 11 12 13

Patent Number Title Of Patent Date Issued
5432264 Recombinant 3-des-OH-cystatin C produced by expression in a procaryotic host cell Jul. 11, 1995
5424198 Human tPA production using vectors coding for DHFR protein Jun. 13, 1995
5422249 Process for the manufacture of thrombin inhibitors Jun. 6, 1995
5420252 Human antithrombin III mutants May. 30, 1995
5409895 Protease inhibitory polypeptides derived from urinary trypsin inhibitor and compositions thereof Apr. 25, 1995
5407915 Human Bikunin variants as proteinase inhibitors, and medicaments containing these Apr. 18, 1995
5378614 Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast Jan. 3, 1995
5373090 Aprotinin analogues and a process for the production thereof Dec. 13, 1994
5367063 Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis Nov. 22, 1994
5340922 Neural calcium-activated neutral proteinase inhibitors Aug. 23, 1994
5320950 DNA encoding anticoagulative protein PP4-X, and its preparation and use Jun. 14, 1994
5312736 Anticoagulant analogues of the tissue factor extrinsic pathway inhibitor (EPI) with reduced affinity for heparin May. 17, 1994
5310892 Nucleic acid sequence which codes for and expresses human fibrillarin and uses thereof May. 10, 1994
5308756 Protein S chromogenic assay May. 3, 1994
5304474 Hydrophobic peptide esters and amides Apr. 19, 1994
5298400 Polynucleotide constructs for secreted glycosylated plasminogen activator inhibitor-2 (PAI-2) Mar. 29, 1994
5294698 Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis Mar. 15, 1994
5279956 Activated protein C polypeptides and anti-peptide antibodies, diagnostic methods and systems for inhibiting activated protein C Jan. 18, 1994
5278285 Variant of Kunitz-type inhibitor derived from the .alpha.3-chain of human type VI collagen produced by recombinant DNA technology Jan. 11, 1994
5278049 Recombinant molecule encoding human protease nexin Jan. 11, 1994
5278144 Antithrombosis agents Jan. 11, 1994
5268291 Human t-PA production using vectors coding for DHFR protein Dec. 7, 1993
5266465 .alpha.-1-antichymotrypsin, analogues and methods of production Nov. 30, 1993
5264550 Human anti-inflammatory phospholipase inhibitor protein Nov. 23, 1993
5252725 .alpha.-1-antichymotrypsin, analogues and methods of production Oct. 12, 1993
5242810 Bifunctional inhibitors of thrombin and platelet activation Sep. 7, 1993
5240841 E. coli resistance to Q.beta. virus infection Aug. 31, 1993
5231010 Recombinant aprotinin variants genetically engineered process for the microbial preparation of homogeneously processed aprotinin variants and the therapeutic use thereof Jul. 27, 1993
5223610 Cholera toxin gene regulated by growth hormone promoter Jun. 29, 1993
5223605 Interleukin-4 binding protein-.gamma. Jun. 29, 1993
5223482 Recombinant Alzheimer's protease inhibitory amyloid protein and method of use Jun. 29, 1993
5218092 Modified granulocyte-colony stimulating factor polypeptide with added carbohydrate chains Jun. 8, 1993
5202419 Anticoagulative protein PP4-X Apr. 13, 1993
5180668 Hirudin derivative Jan. 19, 1993
5180667 Genes encoding eglin C mutants Jan. 19, 1993
5179081 Method of treatment using an anticoagulant polypeptide Jan. 12, 1993
5164482 Recombinant aprotinin variants genetically engineered process for the microbial preparation of homogeneously processed aprotinin variants and the therapeutic use thereof Nov. 17, 1992
5162208 Saccharomyces cerevisiae strain productive of a heterologous protein and process for preparing the said heterologous protein by fermentation of the said strain Nov. 10, 1992
5151509 Gene encoding serine protease inhibitor Sep. 29, 1992
5149636 Method for introducing cloned, amplifiable genes into eucaryotic cells and for producing proteinaceous products Sep. 22, 1992
5139939 Process for the production of human tissue plasminogen activator and cell strain useful therefor Aug. 18, 1992
5135854 Methods of regulating protein glycosylation Aug. 4, 1992
5126322 Pancreatic secretory tryspin inhibitor and variants thereof produced by a recombinant host therefore and pharmaceutical use thereof Jun. 30, 1992
5122458 Use of a bGH gDNA polyadenylation signal in expression of non-bGH polypeptides in higher eukaryotic cells Jun. 16, 1992
5122594 Modified human pancreatic secretory trypsin inhibitor Jun. 16, 1992
5118668 Variants of bovine pancreatic trypsin inhibitor and pharmaceutical use thereof Jun. 2, 1992
5118790 Analogs of hirudin Jun. 2, 1992
5116942 Protein having an inflammatory phospholipase A.sub.2 inhibitory activity May. 26, 1992
5108909 Expression of TPA in mammalian cells Apr. 28, 1992
5106747 Method for enzymatic regeneration of cell culture media and media kits therefor Apr. 21, 1992

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