| |
 |
|
Class Information
Number: 435/464
Name: Chemistry: molecular biology and microbiology > Process of mutation, cell fusion, or genetic modification > Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell > Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.)
Description: Processes wherein copy number of a segment of the nucleic acid within the cell, e.g., a gene, etc., is increased in tandem or head-to-tail fashion without a concomitant increase in the copy number of the entire nucleic acid molecule.
Patents under this class:
| Patent Number |
Title Of Patent |
Date Issued |
| 7294500 |
Mosaic infectious bursal disease virus vaccines |
Nov. 13, 2007 |
| 6444441 |
Production of human mutated proteins in human cells by means of homologous recombination |
Sep. 3, 2002 |
| 6365394 |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus |
Apr. 2, 2002 |
| 6218123 |
Construction of normalized cDNA libraries from eucaryotic cells |
Apr. 17, 2001 |
| 6080575 |
Nucleic acid construct for expressing active substances which can be activated by proteases, and preparation and use |
Jun. 27, 2000 |
| 6069296 |
Regulators of G-protein signalling |
May. 30, 2000 |
| 5981214 |
Production of proteins using homologous recombination |
Nov. 9, 1999 |
| 5976833 |
Method for animal cell culture |
Nov. 2, 1999 |
| 5922583 |
Methods for production of recombinant plasmids |
Jul. 13, 1999 |
| 5879919 |
Method of using eukaryotic expression vectors comprising the BK virus enhancer |
Mar. 9, 1999 |
| 5854021 |
Enhance protein production method |
Dec. 29, 1998 |
| 5807742 |
Neurokinin receptor cell lines |
Sep. 15, 1998 |
| 5776746 |
Gene amplification methods |
Jul. 7, 1998 |
| 5741682 |
Expression induction method |
Apr. 21, 1998 |
| 5691170 |
Generation of hybrid genes and proteins by virus-mediated recombination |
Nov. 25, 1997 |
| 5631158 |
Methods and compositions for high protein production from non-native DNA |
May. 20, 1997 |
| 5578461 |
Gene manipulation and expression using genomic elements |
Nov. 26, 1996 |
| 5561053 |
Method for selecting high-expressing host cells |
Oct. 1, 1996 |
| 5550036 |
Method for co-amplification of human protein C genes in human cells |
Aug. 27, 1996 |
| 5348874 |
Eukaryotic transposable element |
Sep. 20, 1994 |
| 5324643 |
Method of conferring resistance to retroviral infection |
Jun. 28, 1994 |
| 5298400 |
Polynucleotide constructs for secreted glycosylated plasminogen activator inhibitor-2 (PAI-2) |
Mar. 29, 1994 |
| 5272071 |
Method for the modification of the expression characteristics of an endogenous gene of a given cell line |
Dec. 21, 1993 |
| 5256545 |
Sterol Regulatory Elements |
Oct. 26, 1993 |
| 5238820 |
Multiply-amplifiable vectors for high level expression of exogenuos DNA |
Aug. 24, 1993 |
| 5236838 |
Enzymatically active recombinant glucocerebrosidase |
Aug. 17, 1993 |
| 5219738 |
Animal cell transformant, method for obtaining the transformant and method for producing desired foreign gene product by using the transformant |
Jun. 15, 1993 |
| 5198349 |
Method for producing factor VIII:C and analogs |
Mar. 30, 1993 |
| 5168051 |
Nucleic acid encoding TGF-.beta. its uses |
Dec. 1, 1992 |
| 5155020 |
Recombinant poxvirus host range selection system |
Oct. 13, 1992 |
| 5149636 |
Method for introducing cloned, amplifiable genes into eucaryotic cells and for producing proteinaceous products |
Sep. 22, 1992 |
| 5122464 |
Method for dominant selection in eucaryotic cells |
Jun. 16, 1992 |
| 5082774 |
Recombinant human nerve growth factor |
Jan. 21, 1992 |
| 5081028 |
Preparation of transformed hosts which express binding factor related polypeptides |
Jan. 14, 1992 |
| 5057417 |
Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein |
Oct. 15, 1991 |
| 5043270 |
Intronic overexpression vectors |
Aug. 27, 1991 |
| 5017478 |
Transfected cells containing plasmids having genes oriented in opposing directions and methods of using |
May. 21, 1991 |
| 5011776 |
Shuttle vector, utilizing the E. coli asparagine synthetase gene, and capable of dominant transfection and amplification in animal cells |
Apr. 30, 1991 |
| 5011795 |
Human tPA production using vectors coding for DHFR protein |
Apr. 30, 1991 |
| 5010002 |
Human t-PA production using vectors coding DHFR protein |
Apr. 23, 1991 |
| 4996152 |
Avian herpesvirus amplicon as a eucaryotic expression vector |
Feb. 26, 1991 |
| 4992367 |
Enhanced expression of human interleukin-2 in mammalian cells |
Feb. 12, 1991 |
| 4975369 |
Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen |
Dec. 4, 1990 |
| 4965196 |
Polycistronic expression vector construction |
Oct. 23, 1990 |
| 4965199 |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
Oct. 23, 1990 |
| 4889803 |
Production of interferon gamma |
Dec. 26, 1989 |
| 4839284 |
Murine host-vector system capable of amplifying and expressing transfected genes |
Jun. 13, 1989 |
| 4822736 |
Amplification of adenosine deaminase genes in mammalian cells using adenosine, alanosine, uridine, and deoxycoformycin |
Apr. 18, 1989 |
| 4784950 |
Expression of factor VII activity in mammalian cells |
Nov. 15, 1988 |
| 4766067 |
Gene amplification |
Aug. 23, 1988 |
|
|
|
