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Class Information
Number: 435/459
Name: Chemistry: molecular biology and microbiology > Process of mutation, cell fusion, or genetic modification > Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell > Involving particle-mediated transfection (i.e., biolistic transfection)
Description: Processes wherein the nucleic acid is present upon or within a particle which is inserted into the cell, wherein said particle penetrates the cell membrane in a ballistic fashion, i.e., due to a relatively high velocity.

Patents under this class:
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Patent Number Title Of Patent Date Issued
8524368 Charge-dynamic polymers and delivery of anionic compounds Sep. 3, 2013
8513019 Apparatus and method for genetically transforming cells Aug. 20, 2013
8435791 Controlled laser treatment for non-invasive tissue alteration, treatment and diagnostics with minimal collateral damage May. 7, 2013
8415160 Transfection with micro explosion enacted by coated dry ice particles Apr. 9, 2013
8349364 Nucleic acid coated particles suitable for temporary storage Jan. 8, 2013
8343766 Method and apparatus for sustaining viability of biological cells on a substrate Jan. 1, 2013
8323976 Alterations utilizing nanoparticles Dec. 4, 2012
8263406 Enriched or purified population of motor neurons and its preparation from a population of embryonic stem cells Sep. 11, 2012
8153432 Multiplex automated genome engineering Apr. 10, 2012
8133580 Coating composition for a urinary catheter Mar. 13, 2012
8097277 Charge-dynamic polymers and delivery of anionic compounds Jan. 17, 2012
7981446 Pharmaceutical compositions and methods for delivering nucleic acids into cells Jul. 19, 2011
7955827 Controlled electroporation and mass transfer across cell membranes Jun. 7, 2011
7927874 Method of transferring substance into cell Apr. 19, 2011
7892836 Pneumatic capillary gun for ballistic delivery of microscopic particles into tissue Feb. 22, 2011
7888102 Cell line for producing coronaviruses Feb. 15, 2011
7883720 Charge-dynamic polymers and delivery of anionic compounds Feb. 8, 2011
7718409 Controlled electroporation and mass transfer across cell membranes May. 18, 2010
7699801 Advanced genetic vaccines Apr. 20, 2010
7544670 HoxD3, HoxA3 and HoxB3 compositions and methods for improved wound healing Jun. 9, 2009
7482319 Vault and vault-like carrier molecules Jan. 27, 2009
7449449 Particle-mediated transformation of vertebrate tissue cells Nov. 11, 2008
7422861 Oligonucleotide transfection screening method Sep. 9, 2008
7402435 Method of transferring a selected molecule into a cell Jul. 22, 2008
7402573 Use of nanoparticles for the DNA administration to a target organ Jul. 22, 2008
7358234 Induction of a protective immune response through microprojectiles coated with a DNA sequence encoding an immunogenic protein Apr. 15, 2008
7344887 Methods and products for delivering biological molecules to cells using multicomponent nanostructures Mar. 18, 2008
7332339 Transferring materials into cells using porous silicon Feb. 19, 2008
7279322 Electrospraying apparatus and method for coating particles Oct. 9, 2007
7176186 Stimulation of cell-mediated immune responses by targeted particulate genetic immunization Feb. 13, 2007
7157439 HoxD3, HoxA3, and HoxB3 compositions and methods for improved wound healing Jan. 2, 2007
7132289 Method for introducing foreign matters into living cells Nov. 7, 2006
7115582 HoxD3 and HoxA3 compositions and methods for improved wound healing Oct. 3, 2006
7105052 Ordered array of magnetized nanorods and associated methods Sep. 12, 2006
7026166 Fluorogenic dyes Apr. 11, 2006
6929950 Microprojectile delivery system and particulate product Aug. 16, 2005
6911586 Garden bean named `210104` Jun. 28, 2005
6875612 Monocyte-specific particulate delivery vehicle Apr. 5, 2005
6870081 Potato cultivar FL1900 Mar. 22, 2005
6869772 Method for labeling individual cells Mar. 22, 2005
6846676 In Vivo production and delivery of erythropoietin or insulinotropin for gene therapy Jan. 25, 2005
6770480 Transferring materials into cells using porous silicon Aug. 3, 2004
6770632 Folypolyglutamyl synthetase gene transfer to enhance antifolate Aug. 3, 2004
6767743 Method and an apparatus for generating shockwave, a method and an apparatus for accelerating particles, an apparatus for delivering drugs, and a method and an apparatus for delivering DNA Jul. 27, 2004
6746869 Electrospraying apparatus and method for coating particles Jun. 8, 2004
6740336 Process for generating multilayered particles May. 25, 2004
6730663 Targeting gene expression to living tissue using jet injection May. 4, 2004
6653113 High efficiency gene targeting in mouse embryonic stem cells Nov. 25, 2003
6642003 Human glucose-dependent insulin-secreting cell line Nov. 4, 2003
6617153 Portable magneto-mechanical delivery device and method for delivery of reactive substances Sep. 9, 2003

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