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Class Information
Number: 435/455
Name: Chemistry: molecular biology and microbiology > Process of mutation, cell fusion, or genetic modification > Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell
Description: Processes of inserting polynucleotide molecules into or rearranging genetic material within an animal cell.

Sub-classes under this class:

Class Number Class Name Patents
435/467 Introducing an oncogene to establish a cell line 74
435/465 Involving co-transfection 210
435/461 Involving electroporation 166
435/464 Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.) 55
435/463 Involving general or homologous recombination (e.g., gene targeting, etc.) 339
435/460 Involving laser treatment of the cell before or during transfection 23
435/459 Involving particle-mediated transfection (i.e., biolistic transfection) 99
435/462 Involving site-specific recombination (e.g., cre-lox, etc.) 183
435/466 The polynucleotide is a shuttle vector or a transiently replicating hybrid vector 96
435/458 The polynucleotide is coated with or encapsulated within a lipid containing material (e.g., liposome, etc.) 456
435/456 The polynucleotide is encapsidated within a virus or viral coat 923

Patents under this class:

Patent Number Title Of Patent Date Issued
8361751 Cells in which activity of the protein involved in transportation of GDP-fucose is reduced or lost Jan. 29, 2013
8361747 Antibodies against human angiopoietin 2 Jan. 29, 2013
8361457 Duplexed parvovirus vectors Jan. 29, 2013
8357535 PURO-DHFR quadrifunctional marker and its use in protein production Jan. 22, 2013
8357531 Immortalized avian cell lines Jan. 22, 2013
8357514 Methods of gene amplification and expression Jan. 22, 2013
8354389 miRNA-regulated differentiation-dependent self-deleting cassette Jan. 15, 2013
8349810 Methods for targeted cleavage and recombination of CCR5 Jan. 8, 2013
8349333 Allergy inhibitor compositions and kits and methods of using the same Jan. 8, 2013
8344114 Antagonists of PCSK9 Jan. 1, 2013
8343765 Gene injection apparatus and gene injection method Jan. 1, 2013
8338179 Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product Dec. 25, 2012
8338170 Methods for purifying endoderm and pancreatic endoderm cells derived from human embryonic stem cells Dec. 25, 2012
8334271 Use of VEGF in the treatment of retarded fetal growth in pregnancy Dec. 18, 2012
8329465 Recombinant cell clones having increased stability and methods of making and using the same Dec. 11, 2012
8323975 Telomere-encoding synthetic DNA nanocircles, and their use for the elongation of telomere repeats Dec. 4, 2012
8323970 Modulation of T cell recruitment Dec. 4, 2012
8323968 Osteopontin for the prediction and treatment of cardiovascular diseases Dec. 4, 2012
8323884 Isolated SNARE YKT6 genomic polynucleotide fragments from chromosome 7 and their uses Dec. 4, 2012
8318496 Compounds and methods for improving cellular uptake of oligomeric compounds Nov. 27, 2012
8318495 Hematopoietic progenitor cell gene transduction Nov. 27, 2012
8318494 Genetic material and chromosomal processing and manipulation methods Nov. 27, 2012
8318487 Materials and methods relating to the production and maintenance of cell lines Nov. 27, 2012
8318480 Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor Nov. 27, 2012
8318155 Nucleic acid cleaving agent Nov. 27, 2012
8314072 Antisense antibacterial method and compound Nov. 20, 2012
8313925 Zinc finger proteins and method for inactivating a dhfr gene in a chinese hamster ovary cell Nov. 20, 2012
8313900 Isolated DNA directed 50kD regulatory subunit (POLD2) genomic polynucleotide fragments from chomosome 7 and their uses Nov. 20, 2012
8313899 Isolated snare YKT6 genomic polynucleotide fragments from chomosome 7 and their uses Nov. 20, 2012
8309529 Tumour growth inhibitory compounds and methods of their use Nov. 13, 2012
8309355 Methods of treating Parkinson's disease using viral vectors Nov. 13, 2012
8309349 Cell line Nov. 13, 2012
8304240 Microinjection method and device Nov. 6, 2012
8304234 Compositions and methods for delivery of genetic material Nov. 6, 2012
8298826 Chimaeric vector system Oct. 30, 2012
8298816 Expression systems using mammalian beta-actin promoter Oct. 30, 2012
8298790 Methods for effectively coexpressing IL-12 and IL-23 Oct. 30, 2012
8293717 Materials and methods for prevention and treatment of RNA viral diseases Oct. 23, 2012
8283170 Immunoglobulin display vectors Oct. 9, 2012
8278107 Compositions and methods for regulating RNA translation via CD154 CA-dinucleotide repeat Oct. 2, 2012
8278104 Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 Oct. 2, 2012
8273871 Structurally designed shRNAs Sep. 25, 2012
8273723 Compositions and methods for improved glycoprotein sialylation Sep. 25, 2012
8268756 Mixture of binding proteins Sep. 18, 2012
8263406 Enriched or purified population of motor neurons and its preparation from a population of embryonic stem cells Sep. 11, 2012
8263398 Promoter and viral vector containing the same Sep. 11, 2012
8263393 Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors Sep. 11, 2012
8263068 Modified cells expressing a protein that modulates activity of bHLH proteins, and uses thereof Sep. 11, 2012
8258107 Immunostimulatory method Sep. 4, 2012
8257945 Identification of eukaryotic internal ribosome entry site (IRES) elements Sep. 4, 2012

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