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Class Information
Number: 435/455
Name: Chemistry: molecular biology and microbiology > Process of mutation, cell fusion, or genetic modification > Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell
Description: Processes of inserting polynucleotide molecules into or rearranging genetic material within an animal cell.

Sub-classes under this class:

Class Number Class Name Patents
435/467 Introducing an oncogene to establish a cell line 74
435/465 Involving co-transfection 210
435/461 Involving electroporation 166
435/464 Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.) 55
435/463 Involving general or homologous recombination (e.g., gene targeting, etc.) 339
435/460 Involving laser treatment of the cell before or during transfection 23
435/459 Involving particle-mediated transfection (i.e., biolistic transfection) 99
435/462 Involving site-specific recombination (e.g., cre-lox, etc.) 183
435/466 The polynucleotide is a shuttle vector or a transiently replicating hybrid vector 96
435/458 The polynucleotide is coated with or encapsulated within a lipid containing material (e.g., liposome, etc.) 456
435/456 The polynucleotide is encapsidated within a virus or viral coat 923

Patents under this class:

Patent Number Title Of Patent Date Issued
8444965 Tumor cells from immune privileged sites as base cells for cell-based cancer vaccines May. 21, 2013
8440880 Xenorhabdus sp. genome sequences and uses thereof May. 14, 2013
8440810 Riboswitches, methods for their use, and compositions for use with riboswitches May. 14, 2013
8435960 Devices for improved wound management May. 7, 2013
8435791 Controlled laser treatment for non-invasive tissue alteration, treatment and diagnostics with minimal collateral damage May. 7, 2013
8435790 Methods of modulating lipid concentrations in eukaryotic cells May. 7, 2013
8431119 Pharmaceutical compositions and utilization thereof particularly for the treatment of neurodegenerative diseases Apr. 30, 2013
8426570 Recombinant expression vector for animal cell Apr. 23, 2013
8426198 In vitro differentiated cell and human embryonic stem cell population Apr. 23, 2013
8426131 Method for screening candidate compounds for antitumor drug Apr. 23, 2013
8420782 Modular DNA-binding domains and methods of use Apr. 16, 2013
8420396 Conjugates and processes for their preparation and their use for transporting molecules across biological membranes Apr. 16, 2013
8420377 Transgenomic mitochondria, transmitochondrial cells and organisms, and methods of making and using Apr. 16, 2013
8415323 MicroRNAs for inhibiting viral replication Apr. 9, 2013
8415318 Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy Apr. 9, 2013
8415317 Adjuvant compositions and methods for enhancing immune responses to polynucleotide-based vaccines Apr. 9, 2013
8410072 Use of a growth-stimulating protein Apr. 2, 2013
8410071 Potent LNA oligonucleotides for the inhibition of HIF-1A expression Apr. 2, 2013
8410068 Compounds for the treatment or alleviation of edema, and methods for their use Apr. 2, 2013
8409861 Targeted deletion of cellular DNA sequences Apr. 2, 2013
8404453 High affinity binding site of HGFR and methods for identification of antagonists thereof Mar. 26, 2013
8399647 Alpha5-beta1 antibodies and their uses Mar. 19, 2013
8399645 Chimeric receptors with 4-1BB stimulatory signaling domain Mar. 19, 2013
8399422 Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications Mar. 19, 2013
8399257 Transposition of maize Ac/Ds elements in vertebrates Mar. 19, 2013
8399256 Method for introducing gene into cell, and composition for use in the method Mar. 19, 2013
8399249 Procedure for the generation of a high producer cell line for the expression of a recombinant anti-CD34 antibody Mar. 19, 2013
8399219 Protease activatable interferon alpha proprotein Mar. 19, 2013
8399185 Regulators of NFAT Mar. 19, 2013
8389489 Modulators of coagulation factors Mar. 5, 2013
8389487 siRNA-mediated gene silencing of synuclein Mar. 5, 2013
8389484 Methods for targeting RNA molecules Mar. 5, 2013
8389282 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes Mar. 5, 2013
8389281 Materials and methods relating to the production and maintenance of cell lines Mar. 5, 2013
8389276 Immortalized mouse fibroblast cell lines deficient in Bax and/or Bak Mar. 5, 2013
8383804 Group of nucleic acid fragments for prevention of HIV infection or AIDS and the usage thereof Feb. 26, 2013
8383803 PITX3 expression promoters Feb. 26, 2013
8383800 MK167 mini-promoters Feb. 26, 2013
8383364 Inducible expression systems Feb. 26, 2013
8383102 Fusion of peptidoglycan hydrolase enzymes to a protein transduction domain allows eradication of both extracellular and intracellular gram positive pathogens Feb. 26, 2013
8377674 Method for producing genetically-modified cells with rationally-designed meganucleases with altered sequence specificity Feb. 19, 2013
8372817 Small interfering RNA for gene knockdown of the subcutaneous N-methyl-D-aspartate receptor NR1 subunit, and it's application on pharmaceutics Feb. 12, 2013
8367344 Method of detecting oncogenesis of hematopoietic cells Feb. 5, 2013
8367057 Stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them Feb. 5, 2013
8361982 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell Jan. 29, 2013
8361976 Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules Jan. 29, 2013
8361797 Myeloma cell culture in transferrin-free low iron medium Jan. 29, 2013
8361788 Immortalized avian cell lines comprising E1A nucleic acid sequences Jan. 29, 2013
8361787 Method for expression of small RNA molecules within a cell Jan. 29, 2013
8361760 Microbial production of 3-hydroxyacids from glucose and glycolate Jan. 29, 2013

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