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Class Information
Number: 435/455
Name: Chemistry: molecular biology and microbiology > Process of mutation, cell fusion, or genetic modification > Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell
Description: Processes of inserting polynucleotide molecules into or rearranging genetic material within an animal cell.

Sub-classes under this class:

Class Number Class Name Patents
435/467 Introducing an oncogene to establish a cell line 74
435/465 Involving co-transfection 210
435/461 Involving electroporation 166
435/464 Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.) 55
435/463 Involving general or homologous recombination (e.g., gene targeting, etc.) 339
435/460 Involving laser treatment of the cell before or during transfection 23
435/459 Involving particle-mediated transfection (i.e., biolistic transfection) 99
435/462 Involving site-specific recombination (e.g., cre-lox, etc.) 183
435/466 The polynucleotide is a shuttle vector or a transiently replicating hybrid vector 96
435/458 The polynucleotide is coated with or encapsulated within a lipid containing material (e.g., liposome, etc.) 456
435/456 The polynucleotide is encapsidated within a virus or viral coat 923

Patents under this class:

Patent Number Title Of Patent Date Issued
8530232 Defective Sindbis viral vector comprising an anti-tumor gene Sep. 10, 2013
8524678 Method for delivering genes Sep. 3, 2013
8524500 Methods and compositions for targeted cleavage and recombination Sep. 3, 2013
8524498 Methods and compositions for homologous recombination in human cells Sep. 3, 2013
8524368 Charge-dynamic polymers and delivery of anionic compounds Sep. 3, 2013
8519101 Nucleic acid encoding a silk protein and a method of producing a silk thread using same Aug. 27, 2013
8518871 Skin permeating and cell entering (SPACE) peptides and methods of use thereof Aug. 27, 2013
8518701 Methods and materials for producing transgenic artiodactyls Aug. 27, 2013
8518700 Composition for reprogramming somatic cells to generate induced pluripotent stem cells, comprising Bmi1 and low molecular weight substance, and method for generating induced pluripotent stem c Aug. 27, 2013
8518699 Methods for genetic diversification in gene conversion active cells Aug. 27, 2013
8518403 Expression-enhanced polypeptides Aug. 27, 2013
8513486 Cell nuclear transfer Aug. 20, 2013
8513019 Apparatus and method for genetically transforming cells Aug. 20, 2013
8513018 Immortalized avian cell lines Aug. 20, 2013
8513017 Methods and products for biasing cellular development Aug. 20, 2013
8513005 DNA immunogenic composition comprising a full-length modified poxvirus L1R gene fused to a tPA leader sequence Aug. 20, 2013
8507277 Nonviral vectors for delivering polynucleotides Aug. 13, 2013
8506969 Efficient cell culture system for hepatitis C virus genotype 7a Aug. 13, 2013
8506948 UCB-MSCs comprising a tumor suppressor gene reduce the size of an IL-8 or GRO-.alpha.expressing tumor Aug. 13, 2013
8501705 Methods and materials for treating autoimmune and/or complement mediated diseases and conditions Aug. 6, 2013
8501478 Trehalose click polymers for delivery of biologically active molecules Aug. 6, 2013
8501464 Lentiviral vectors carrying synthetic bi-directional promoters and uses thereof Aug. 6, 2013
8501191 FGFR2-IIIb fusion proteins and methods of making them Aug. 6, 2013
8492151 Processes and compositions for transfecting chinese hamster ovary (CHO) cells Jul. 23, 2013
8492141 Neostatins Jul. 23, 2013
8486908 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Jul. 16, 2013
8486701 ETS2 and MESP1 generate cardiac progenitors from fibroblasts Jul. 16, 2013
8486694 Generation of antigen specific T cells Jul. 16, 2013
8486385 Methods for therapy of neurodegenerative disease of the brain Jul. 16, 2013
8481689 Antibody specifically binding to c-Met and methods of use Jul. 9, 2013
8476419 Enhancing the T-cells stimulatory capacity of human antigen presenting cells and their use in vaccination Jul. 2, 2013
8476246 Combination of a chemotherapeutic agent and an inhibitor of the TGF-beta system Jul. 2, 2013
8470998 Positive controls for expression modulating experiments Jun. 25, 2013
8470973 Modular DNA-binding domains and methods of use Jun. 25, 2013
8470796 Treatment of cancer by inhibition of IGFBPs and clusterin Jun. 25, 2013
8470552 Strategy to reduce lactic acid production and control PH in animal cell culture Jun. 25, 2013
8466121 Method of selectively inhibiting the activity of ACAT1 in the treatment of Alzheimer's disease Jun. 18, 2013
8466118 Modulation of blood brain barrier protein expression Jun. 18, 2013
8465732 Endothelial cells expressing adenovirus E4ORF1 and methods of use thereof Jun. 18, 2013
8461127 p27 and p21 in gene therapies Jun. 11, 2013
8460933 Expression system incorporating a capsid promoter sequence as an enhancer Jun. 11, 2013
8460932 Method of treating a disorder by suicide gene therapy Jun. 11, 2013
8455453 Use of VEGF-D gene to prevent restenosis Jun. 4, 2013
8455219 Mammalian expression vectors and uses thereof Jun. 4, 2013
8454974 Adaptive mutations allow establishment of JFH1-based cell culture systems for hepatitis C virus genotype 4A Jun. 4, 2013
8445666 Ribonucleic acid interference molecules May. 21, 2013
8445655 Functional nucleic acid ligands to fluorescent proteins May. 21, 2013
8445268 Her-2/neu DNA vaccine having anti-cancer activity May. 21, 2013
8445249 Sso7-polymerase conjugate proteins May. 21, 2013
8445229 Methods of generating high-production of antibodies from hybridomas created by in vitro immunization May. 21, 2013

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