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Class Information
Number: 435/455
Name: Chemistry: molecular biology and microbiology > Process of mutation, cell fusion, or genetic modification > Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell
Description: Processes of inserting polynucleotide molecules into or rearranging genetic material within an animal cell.

Sub-classes under this class:

Class Number Class Name Patents
435/467 Introducing an oncogene to establish a cell line 74
435/465 Involving co-transfection 210
435/461 Involving electroporation 166
435/464 Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.) 55
435/463 Involving general or homologous recombination (e.g., gene targeting, etc.) 339
435/460 Involving laser treatment of the cell before or during transfection 23
435/459 Involving particle-mediated transfection (i.e., biolistic transfection) 99
435/462 Involving site-specific recombination (e.g., cre-lox, etc.) 183
435/466 The polynucleotide is a shuttle vector or a transiently replicating hybrid vector 96
435/458 The polynucleotide is coated with or encapsulated within a lipid containing material (e.g., liposome, etc.) 456
435/456 The polynucleotide is encapsidated within a virus or viral coat 923

Patents under this class:

Patent Number Title Of Patent Date Issued
8617533 Multi-antigenic alphavirus replicon particles and methods Dec. 31, 2013
8614295 Antibody molecules having specificity for human OX40 Dec. 24, 2013
8614094 Compositions and methods for determining genetic polymorphisms in the TMEM216 gene Dec. 24, 2013
8603823 Methods and compositions for producing vitamin K dependent proteins Dec. 10, 2013
8598332 Methods and means for obtaining modified phenotypes Dec. 3, 2013
8598331 CLDN5 mini-promoters Dec. 3, 2013
8598328 Tol1 factor transposase and DNA introduction system using the same Dec. 3, 2013
8598143 Sequence-specific inhibition of small RNA function Dec. 3, 2013
8597949 Methods and compositions for modulating RAD51 and homologous recombination Dec. 3, 2013
8597912 Methods and compositions for generation of Bax-and Bak-deficient cell lines Dec. 3, 2013
8592390 Immunostimulatory method Nov. 26, 2013
8592387 Methods for treating or preventing heart damage with integrin-linked kinase (ILK) compositions Nov. 26, 2013
8592211 Enhanced PiggyBac transposon and methods for transposon mutagenesis Nov. 26, 2013
8592206 Culture based screening assay and methods of use thereof to identify agents which modulate tumor development, invasion and differentiation Nov. 26, 2013
8586560 Exon skipping therapy for dysferlinopathies Nov. 19, 2013
8586364 Cells and methodology to generate non-segmented negative-strand RNA viruses Nov. 19, 2013
8586358 HLA homozygous cells Nov. 19, 2013
8586294 Detection of protein translocation by beta-galactosidase reporter fragment complementation Nov. 19, 2013
8586028 Synthetic herpes simplex viruses type-1 for treatment of cancers Nov. 19, 2013
8581021 Pig whose genome comprises a heterologous site-specific recombination site and a transpohon tag Nov. 12, 2013
8580936 Polynucleotides encoding FGFR1-IIIc ECD fusion proteins Nov. 12, 2013
8580273 TNF superfamily member light fusion proteins Nov. 12, 2013
8575328 Formicidae (ant) control using double-stranded RNA constructs Nov. 5, 2013
8575327 Conserved HBV and HCV sequences useful for gene silencing Nov. 5, 2013
8569471 Stem cell beacon Oct. 29, 2013
8569257 Method for modulating responsiveness to steroids Oct. 29, 2013
8569251 Use of microwave irradiation for delivery of macromolecules Oct. 29, 2013
8569065 Compositions and methods for the delivery of biologically active RNAs Oct. 29, 2013
8569054 Mammalian cell lines for increasing longevity and protein yield from a cell culture Oct. 29, 2013
8563500 Methods and compounds for treating diseases caused by reactive oxygen species Oct. 22, 2013
8563314 Methods and compositions for modulating PD1 Oct. 22, 2013
8563313 Macrophage cell-lines for propagation of porcine reproductive and respiratory syndrome virus Oct. 22, 2013
8557972 Compositions and methods for transfection of RNA and controlled stabilization of transfected RNA Oct. 15, 2013
8557584 Preparing a homogenous population of stem cells committed to differentiated to a specific cell type Oct. 15, 2013
8552170 Expression vector for establishing highly productive cell and the highly productive cell Oct. 8, 2013
8552168 Nucleic acids for inducing expression of transcripts and proteins and methods for making and using them Oct. 8, 2013
8551968 Methods for generation of antibodies Oct. 8, 2013
8551774 Expression vectors containing a truncated epstein barr nuclear antigen 1 lacking the Gly-Gly-Ala domain for enhanced transient gene expression Oct. 8, 2013
8546544 Antibody specifically binding to c-Met and methods of use Oct. 1, 2013
8546347 Composition for treatment and improvement of diabetes comprising caveolin as active ingredient and a method for treatment of diabetes using it Oct. 1, 2013
8546143 Compositions and methods for inhibiting expression of a target gene Oct. 1, 2013
8546141 Method for preparation of platelet from iPS cell Oct. 1, 2013
8546140 Methods for the production of iPS cells using non-viral approach Oct. 1, 2013
8546105 Engineering intracellular sialylation pathways Oct. 1, 2013
8546090 SIRT4 activities Oct. 1, 2013
8541390 Treatment of cancer by inhibition of IGFBPs and clusterin Sep. 24, 2013
8541237 Method for diagnosing disease using adenovirus harboring trans-splicing ribozyme by molecular imaging Sep. 24, 2013
8541222 Modified microorganisms with inactivated lactate dehydrogenase gene Sep. 24, 2013
8540992 Methods and vectors for generating asialylated immunoglobulins Sep. 24, 2013
8530238 Method of efficiently establishing induced pluripotent stem cells Sep. 10, 2013

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