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Class Information
Number: 435/455
Name: Chemistry: molecular biology and microbiology > Process of mutation, cell fusion, or genetic modification > Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell
Description: Processes of inserting polynucleotide molecules into or rearranging genetic material within an animal cell.










Sub-classes under this class:

Class Number Class Name Patents
435/467 Introducing an oncogene to establish a cell line 74
435/465 Involving co-transfection 210
435/461 Involving electroporation 166
435/464 Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.) 55
435/463 Involving general or homologous recombination (e.g., gene targeting, etc.) 339
435/460 Involving laser treatment of the cell before or during transfection 23
435/459 Involving particle-mediated transfection (i.e., biolistic transfection) 99
435/462 Involving site-specific recombination (e.g., cre-lox, etc.) 183
435/466 The polynucleotide is a shuttle vector or a transiently replicating hybrid vector 96
435/458 The polynucleotide is coated with or encapsulated within a lipid containing material (e.g., liposome, etc.) 456
435/456 The polynucleotide is encapsidated within a virus or viral coat 923


Patents under this class:
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Patent Number Title Of Patent Date Issued
7785886 Methods and reagents for modulating cholesterol levels Aug. 31, 2010
7785880 Mammalian cell lines for increasing longevity and protein yield from cell culture Aug. 31, 2010
7785874 Compositions and methods for monosynaptic transport Aug. 31, 2010
7785831 Compositions and methods for non-targeted activation of endogenous genes Aug. 31, 2010
7785792 Targeted modification of chromatin structure Aug. 31, 2010
7781574 Chimeric osteogenic factor containing proteins capable of increased nuclear localization and methods of use thereof Aug. 24, 2010
7781214 Lineage specific cells and progenitor cells Aug. 24, 2010
7781208 Methods and means for targeted gene delivery Aug. 24, 2010
7776836 RNA aptamers and methods for identifying the same Aug. 17, 2010
7776600 Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids Aug. 17, 2010
7776599 Method of enhancing homologous recombination of somatic cells and method of constructing specific antibody Aug. 17, 2010
7776595 Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells Aug. 17, 2010
7776552 Mammalian IAP gene family, primers, probes and detection methods Aug. 17, 2010
7772003 Lipid derivatives of aminoglycosides Aug. 10, 2010
7767456 Non-viral gene delivery system Aug. 3, 2010
7767455 Nucleus export reporter system Aug. 3, 2010
7767454 Methods for mutating genes in cells using insertional mutagenesis Aug. 3, 2010
7767201 Vascular cells genetically altered to over-express angiogenic proliferation and maturation factors; treatment of atherosclerosis using same Aug. 3, 2010
7763466 Mesoderm and definitive endoderm cell populations Jul. 27, 2010
7763461 Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyl transferase Jul. 27, 2010
7763446 Chimeric DNA-binding proteins Jul. 27, 2010
7759519 Amide and peptide derivatives of dialkylenetriamines and their use as transfection agents Jul. 20, 2010
7759121 Methods for generating hypermutable yeast Jul. 20, 2010
7754202 Methods of controlling cell differentiation and growth using a fusion protein and a drug Jul. 13, 2010
7749753 Cells in which activity of the protein involved in transportation of GDP-fucose is reduced or lost Jul. 6, 2010
7749745 Viral vectors and their use in therapeutic methods Jul. 6, 2010
7749733 Nucleic acid sequences having gene transcription regulatory qualities Jul. 6, 2010
7749492 AAV vectors and methods Jul. 6, 2010
7749491 Compounds and methods to enhance rAAV transduction Jul. 6, 2010
7745179 Lentiviral vectors featuring liver specific transcriptional enhancer and methods of using same Jun. 29, 2010
7745140 Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool Jun. 29, 2010
7741306 Regulation of oncogenes by microRNAs Jun. 22, 2010
7741302 Transposase and method of gene modification Jun. 22, 2010
7741301 Transposase and method of gene modification Jun. 22, 2010
7741080 Adiponectin expression-inducing agents and uses thereof Jun. 22, 2010
7741079 Method of making a genetically modified mammalian cell Jun. 22, 2010
7741077 Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins Jun. 22, 2010
7740871 Cancer immunotherapy with a viral antigen-defined, immunomodulator-secreting cell vaccine Jun. 22, 2010
7740835 Anaerobic bacterium as a drug for cancer gene therapy Jun. 22, 2010
7737265 RNAi modulation of HIF-1 and therapeutic uses thereof Jun. 15, 2010
7737253 Human cancer stem cell culture compositions comprising Erbb2 variants and methods of use thereof Jun. 15, 2010
7737124 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell Jun. 15, 2010
7736898 Thiaminases and thiaminase genes for use in apoptotic therapies Jun. 15, 2010
7736870 Nucleic acid sequences having gene transcription regulatory qualities Jun. 15, 2010
7736869 Nucleic acid sequences having gene transcription regulatory qualities Jun. 15, 2010
7736868 Nucleic acid sequences having gene transcription regulatory qualities Jun. 15, 2010
7732659 Injecting Drosophila embryos Jun. 8, 2010
7732206 Oligodendrocyte determination genes and uses thereof Jun. 8, 2010
7732203 Method for transdifferentiating mesenchymal stem cells into neuronal cells Jun. 8, 2010
7732195 Tethered vectors for cell surface immunoglobulin display Jun. 8, 2010

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