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Class Information
Number: 435/359
Name: Chemistry: molecular biology and microbiology > Animal cell, per se (e.g., cell lines, etc.); composition thereof; process of propagating, maintaining or preserving an animal cell or composition thereof; process of isolating or separating an animal cell or composition thereof; process of preparing a composition containing an animal cell; culture media therefore > Rodent cell, per se > Chinese hamster ovary (i.e., cho) > Expressing recombinant tpa
Description: Subject matter wherein the Chinese Hamster ovary cell expresses tissue plasminogen activator (tPA) from a recombinant gene.

Patents under this class:

Patent Number Title Of Patent Date Issued
7423135 .beta.-actin and rpS21 promoters and uses thereof Sep. 9, 2008
7280680 Method and apparatus for observing three-dimensional localizations of in vivo expressed genes as well as method and apparatus for observing minute three-dimensional localizations of in vivo ex Oct. 9, 2007
RE39792 Method for culturing Chinese hamster ovary cells Aug. 21, 2007
7166445 Methods and host cells for improved cell culture Jan. 23, 2007
7091004 Regulation of translation for recombinant protein production Aug. 15, 2006
6667172 Cell and tissue culture modeling device and apparatus and method of using same Dec. 23, 2003
6506598 Cell culture process Jan. 14, 2003
6413744 Methods and host cells for improved cell culture Jul. 2, 2002
5985607 Recombinant DNA molecules and expression vectors for tissue plasminogen activator Nov. 16, 1999
5849574 Human tPA production using vectors coding for DHFR protein Dec. 15, 1998
5763253 Methods of preparing tissue plasiminogen activator derivative composition Jun. 9, 1998
5753486 Human tissue plasminogen activator May. 19, 1998
5736135 Method for making variant secreted proteins with altered properties Apr. 7, 1998
5728565 Methods of preparing tissue plasminogen activator derivatives Mar. 17, 1998
5658759 Recombinant DNA expression vectors Aug. 19, 1997
5658788 Compounds and methods for treatment of thromboembolic disorders Aug. 19, 1997
5646009 Hybrid vector and method resulting in protein overproduction by eukaryotic cells Jul. 8, 1997
5641655 Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide Jun. 24, 1997
5616486 Tissue plasminogen activator having zymogenic or fibrin specific properties Apr. 1, 1997
5614190 Tissue plasminogen activator having zymogenic or fibrin specific properties Mar. 25, 1997
5510248 Stable recombinant meizothrombin-like polypeptides Apr. 23, 1996
5439679 Peptide plasminogen activators Aug. 8, 1995
5407819 Human plasminogen activator variants having amino acids 37-42 substituted and a method for their manufacture Apr. 18, 1995
5346824 DNA encoding variants of tissue plasminogen activators and expression vectors and hosts thereof Sep. 13, 1994
5342775 Plasminogen activator Aug. 30, 1994
5270198 DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells Dec. 14, 1993
5262170 Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells Nov. 16, 1993
5246850 DNA molecules encoding human tissue plasminogen activator variants with decreased clearance, vectors, and host cells Sep. 21, 1993
5244806 DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells Sep. 14, 1993
5242819 DNA molecules encoding hybrid proteins of tissue plasminogen activator and urokinase Sep. 7, 1993
5219738 Animal cell transformant, method for obtaining the transformant and method for producing desired foreign gene product by using the transformant Jun. 15, 1993
5147643 DNA sequences encoding human t-PA substituted at position 275 or at positions 275 and 277 and pharmaceutical compositions Sep. 15, 1992
5122458 Use of a bGH gDNA polyadenylation signal in expression of non-bGH polypeptides in higher eukaryotic cells Jun. 16, 1992
5106741 Tissue plasminogen activator (TPA) analogs Apr. 21, 1992
5087572 DNA encoding human plasminogen modified at the cleavage site Feb. 11, 1992
5010002 Human t-PA production using vectors coding DHFR protein Apr. 23, 1991
4853330 Human tissue plasminogen activator Aug. 1, 1989

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