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Class Information
Number: 435/217
Name: Chemistry: molecular biology and microbiology > Enzyme (e.g., ligases (6. ), etc.), proenzyme; compositions thereof; process for preparing, activating, inhibiting, separating, or purifying enzymes > Hydrolase (3. ) > Acting on peptide bond (e.g., thromboplastin, leucine amino-peptidase, etc., (3.4)) > Plasmin (i.e., fibrinolysin)
Description: Subject matter wherein the enzyme catalyzes the hydrolysis of amide bonds which connect alpha-arginine or alpha-lysine to another amino acid or peptide and converts fibrin to water soluble products.

Patents under this class:
1 2 3

Patent Number Title Of Patent Date Issued
8617863 Composition, method, and kit for preparing plasmin Dec. 31, 2013
8563288 Removal of plasmin or plasminogen from cryoprecipitate Oct. 22, 2013
8440420 Assessment of cardiac health and thrombotic risk in a patient May. 14, 2013
8304205 Blood coagulation assays Nov. 6, 2012
8093035 Pseudomonas sp. strain and method of producing chitinase, chitosanase and nattokinase using the same Jan. 10, 2012
7871608 Reversibly inactivated acidified plasmin Jan. 18, 2011
7837992 C-1 inhibitor prevents non-specific plasminogen activation by a prourokinase mutant without impeding fibrin-specific fibrinolysis Nov. 23, 2010
7544500 Process for the production of a reversibly inactive acidified plasmin composition Jun. 9, 2009
7205139 Tissue plasminogen activator-like protease Apr. 17, 2007
7125569 Removal of plasmin(ogen) from protein solutions Oct. 24, 2006
7070969 Plasmin inhibitors from the australian brown snake Pseudonaja textilis textilis Jul. 4, 2006
6964764 Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin Nov. 15, 2005
6855263 Rapid process for purification and concentration of plasmin Feb. 15, 2005
6846656 Process for producing N-acetylneuraminic acid Jan. 25, 2005
6680174 Assay for growth differentiation factor 9 Jan. 20, 2004
6613769 Tryptase inhibitors Sep. 2, 2003
6585972 Process for crosslinking of collagen in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina Jul. 1, 2003
6576609 Methods and compositions for generating angiostatin Jun. 10, 2003
6569636 Assay for modulators of metallo-enzyme activity May. 27, 2003
6492494 Method of making a fibrin sealant comprising alpha-2-antiplasmin Dec. 10, 2002
6462018 Fibrin polymer structure Oct. 8, 2002
6413931 Peptide inhibitor of fibrinogen blood clotting Jul. 2, 2002
6403556 Pharmaceutical preparation containing protein C and a thrombolytically active substance Jun. 11, 2002
6372473 Tissue plasminogen activator-like protease Apr. 16, 2002
6355243 Method of thrombolysis by local delivery of active plasmin Mar. 12, 2002
6262236 Fibrin sealant compositions and methods for utilizing same Jul. 17, 2001
6239106 Family of protease inhibitors, and other biologic active substances May. 29, 2001
6207066 Method for purification of a blood component Mar. 27, 2001
6190659 Bacterial plasmin binding protein and methods of use thereof Feb. 20, 2001
6183692 Kit for purification of plasmin Feb. 6, 2001
6113897 Antibodies and their use Sep. 5, 2000
6100050 Factor VIII:Ca chromogenic assay Aug. 8, 2000
6068838 Purified multimerase May. 30, 2000
6048966 Fibrin sealant compositions and methods for utilizing same Apr. 11, 2000
5932213 Modified plasmin precursors with resistance to inhibitors of plasmin Aug. 3, 1999
5908625 Use of the protease domain of human plasminogen activator for the treatment of thromboembolic diseases Jun. 1, 1999
5888753 Monoclonal antibodies against the plasmin-antiplasmin complex, a method for the preparation thereof and the use thereof Mar. 30, 1999
5879923 Stable plasmin solution Mar. 9, 1999
5811252 Modified proenzymes as substrates for proteolytic enzymes Sep. 22, 1998
5804428 Fibrin sealant compositions and methods for utilizing same Sep. 8, 1998
5750657 Methods and compositions using fibrin monomer to make a fibrin sealant May. 12, 1998
5750650 Fibrinolytic protein and production method thereof May. 12, 1998
5741771 Thrombolytic composition Apr. 21, 1998
5736512 Serine protease variants having peptide ligase activity Apr. 7, 1998
5723122 Use of the protease domain of human plasminogen activator for the treatment of thromboembolic diseases Mar. 3, 1998
5691295 Detergent compositions Nov. 25, 1997
5688664 Thrombin activatable plasminogen analogues Nov. 18, 1997
5653979 Immunotargeting of plasminogen activators to the pulmonary endothelium Aug. 5, 1997
5648254 Co-expression in eukaryotic cells Jul. 15, 1997
5645833 Inhibitor resistant serine proteases Jul. 8, 1997

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