7.1 through 7.95

Aeration or oxygen transfer technique

Aids related test

Anerobic cultivation

Animal cell, per se (e.g., cell lines, etc.); composition thereof; process of propagating, maintaining or preserving an animal cell or composition thereof; process of isolating or separating an animal cell or composition thereof; process of preparing a composition containing an animal cell; culture media therefore

Animal cell, per se, expressing immunoglobulin, antibody, or fragment thereof

Immunoglobulin or antibody binds a drug, hapten, hapten-carrier complex, or specifically identified chemical structure (e.g., theophylline, digoxin, etc.)

Immunoglobulin or antibody binds a microorganism or normal or mutant component or product thereof (e.g., animal cell, cell surface antigen, secretory product, etc.)

Binds a bacterium or similar microorganism or component or product thereof (e.g., streptococcus, legionella, mycoplasma, bacterium associated antigen, exotoxin, etc.)

Binds a cancer cell or component or product thereof (e.g., cell surface antigen, etc.)

Binds an antigen characterized by name or molecular weight (e.g., cea, nca, cc glycoprotein, melanoma gp 150 antigen, etc.)

Binds a fungus or plant cell or component or product thereof (e.g., fungus associated antigen, etc.)

Binds a hematopoietic cell or component or product thereof (e.g., erythrocyte, granulocyte, macrophage, monocyte, platelet, myelogenous leukemia cell, bone marrow stem cell, granulocytic cell surface antigen, hemoglobin, thrombospondin, glycophorin, etc.)

Binds a lymphocytic or lymphocytic-like cell or component or product thereof (e.g., b cell, b-lineage bone marrow cell, null cell, natural killer cell, b-lymphoblastoid cell, b-lineage, acute lymphoblastic leukemia cell, b-lymphocytic cell surface antigen, etc.)

Binds a t-lymphocytic cell or component or product thereof (e.g., t-cell, thymocyte, t-lineage bone marrow cell, t-lymphoblastoid cell, t-lineage acute lymphoblastic leukemia cell, t-lymphocytic cell surface antigen, etc.)

Binds a hormone or other secreted growth regulatory factor, differentiation factor, intercellular mediator, or neurotransmitter (e.g., insulin, human chorionic gonadotropin, intragonadal regulatory protein, mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine, etc.)

Binds a lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

Binds a nucleic acid or derivative or component thereof (e.g., dna, rna, dna-rna, hybrid, nucleotide, nucleoside, carcinogen-dna adduct, etc.)

Binds a parasitic protozoan or metazoan cell or component or product thereof; (e.g., dirofilaria, eimeria, coccidia, trichinella, parasite cell surface antigen, etc.)

Binds a plasma protein, serum protein, or fibrin (e.g., clotting factor fibrinolytic factor, complement factor, immunoglobulin, apolipoprotein, etc.)

Binds a receptor (e.g., transferrin receptor, fc receptor, dihydropyridine receptor, il-2 receptor, etc.)

Binds a virus or component or product thereof (e.g., virus associated antigen, etc.)

Binds a retrovirus or component or product thereof (e.g., hiv, lav, htlv, etc.)

Binds an enzyme

Immunoglobulin or antibody binds a specifically identified amino acid sequence

Immunoglobulin or antibody binds an expression product of a cancer related gene or fragment thereof (e.g., oncogene, proto-oncogene, etc.)

Immunoglobulin or antibody binds an oligosaccharide structure other than nucleic acid

Immunoglobulin or antibody is anti-idiotypic

Immunoglobulin or antibody is chimeric, mutated, or a recombined hybrid (e.g., bifunctional, bispecific, rodent-human chimeric, single chain, rfv, immunoglobuin fusion protein, etc.)

Avian cell, per se

Canine cell, per se

Culture medium, per se

Contains a growth factor or growth regulator

Contains a polypeptide hormone

Contains an albumin

Contains an animal extract

Feline cell, per se

Fused or hybrid cell, per se

Insect cell, per se

Method of co-culturing cells

Method of culturing cells in suspension

Culture medium contains a growth factor or growth regulator

Medium contains a colony stimulating factor

Medium contains a polypeptide hormone

Medium contains an interleukin

Culture medium contains a transferrin

Culture medium contains an albumin

Culture medium contains an animal extract

Serum

Culture medium contains an incompletely defined plant or microbial extract excluding animal extract

Using airlift or laminar flow aeration or foam culture

Wherein culture vessel is rotated or oscillated or culture is agitated

Method of culturing encapsulated cells

Method of detaching cells, digesting tissue or establishing a primary culture

Digesting tissue with protease

Releasing bound or adhered cell using protease

Using mechanical means (e.g., trituration, etc.)

Method of regulating cell metabolism or physiology

Method of altering the differentiation state of the cell

Method of synchronizing cell division

Method of storing cells in a viable state

Primate cell, per se

Human

Blood, lymphatic, or bone marrow origin or derivative

B-cell or derivative

Myeloma origin or derivative

T-cell or derivative

Epithelial origin or derivative

Hela cell or derivative

Hepatic origin or derivative

Nervous system origin or derivative

Renal origin or derivative

Monkey kidney

Cos (e.g., cos-7, etc.)

Expressing recombinant lymphokine, interferon, hormone, growth factor or morphogen

Rodent cell, per se

Chinese hamster ovary (i.e., cho)

Expressing recombinant antigen

Expressing recombinant hormone or growth factor

Expressing recombinant receptor

Expressing recombinant tpa

Mouse (i.e., mus)

Blood or lymphatic origin or derivative

Fibroblast, fibroblast-like cell or derivative (e.g., nih 3t3, etc.)

L cell or derivative (e.g., ltk(-), etc.)

Rat (i.e., rattus)

Solid support and method of culturing cells on said solid support

Support is a coated or treated surface

Support is a fiber

Fabric, mat, gauze, or fibrous coating

Hollow

Support is a gel surface

Support is a membrane

Support is a resin

Support is a suspendable particle

Two or more cell types, per se, in co-culture

Apparatus

Bioreactor

Bottle, tube, jar, or flask

Flat culture flask

Including multiple internal compartments for baffles

Bubble bioreactor

Composting apparatus

Including agitation means

Compostor is rotatably mounted

Including solid or liquid transport means into or out of a compostor

Cylindrical reaction tank or vessel horizontally disposed with respect to its central axis

With a rotatably mounted tank or vessel

Dish, plate, or tray

Including cover seal

Multicompartmented

Including cover seal

Including a draft tube for agitation

Airlift bioreactor

Including a semi-permeable membrane or filter

Including foam breaking means

Including magnetically coupled agitation means

Including means to transmit light into a bioreactor to facilitate photo- bioreaction (e.g., photosynthesis)

Including off-gas trapping means

Including semipermeable membrane or filter

In combination with a dish, plate, or tray

Including perfusion means

Including a spinning semipermeable membrane or filter

Including hollow fiber or capillary

Including solid extended fluid contact reaction surface

Including a bottle, tube, jar, or flask

Incubator

Including an agitator

Specifically adapted for an anaerobic microorganism or enzyme (e.g., anaerobe jars)

Malting or mashing apparatus

Movable floor to facilitate maintenance (e.g., cleaning)

Vertically spaced stages, levels, or floors

Cascading

With agitator or mash turner

With horizontal axis of rotation

Rotating vessel

With vertical axis of rotation

Tubular or plug flow bioreactor

Radial or spiral flow bioreactor

Vessels or trays in series

Differentiated tissue (e.g., organ) perfusion or preservation apparatus

Including condition or time responsive control means

Including gas flow or pressure control

Including liquid flow, level, or volume control

Including mixing or agitation control

Including position control

Including liquid dispenser means

Plater, streaker, or spreader

Including measuring or testing

Including a bottle, tube, flask, or jar

Including multiple internal compartments or baffles

Including a coated reagent or sample layer

Including a dish, plate, slide, or tray

Including multiple compartments (e.g., wells, etc.)

Including means for fluid passage between compartments (e.g., between wells, etc.)

Including bibulous or absorbent layer

Including multiple, stacked layers

Including column separation means

Including frangible means for introducing a sample or reagent

Including optical measuring or testing means

Means for measuring gas pressure or gas volume of gas evolved from or consumed in an enzymatic or microbial reaction

Measuring or testing for antibody or nucleic acid, or measuring or testing using antibody or nucleic acid

Sterility testing means

With sample or reagent mechanical transport means

Inoculator, streaker, or sampler

Loop or wire streaker

Means for inoculation or sampling of a closed vessel

Replica plate

Involving lysis of a microorganism by means other than comminution

Means for separation or recovery of a microorganism from culture media

Microorganism preservation, storage, or transport apparatus

Mutation or genetic engineering apparatus

Including projectile means

With means for applying an electric current or charge (e.g., electrofusion, electroporation, etc.)

Capture of complex after antigen-antibody reaction

Carrier-bound or immobilized enzyme or microbial cell; carrier-bound or immobilized cell; preparation thereof

Enzyme or microbial cell is immobilized on or in an inorganic carrier

Enzyme or microbial cell is immobilized on or in an organic carrier

Carrier is carbohydrate

Carbohydrate is cellulose or derivative thereof

Carrier is synthetic polymer

Attached to the carrier via a bridging agent

Enzyme or microbial cell is entrapped within the carrier (e.g., gel, hollow fibre)

Multi-enzyme system

Combinatorial chemistry and library technology

Apparatus

For preparing libraries

For screening

Library or combinatorial chemistry related product

Library of biologically replicable entities (e.g., genetic packages, vectors, etc.) or a biologically replicable entity (e.g., genetic packages, vectors, etc.) displaying, containing or presenting the library elements

The entity is a microorganism, animal cell or plant cell

Animal cell

Bacteria or protozoa

Yeast or fungus

The entity is a virus or bacteriophage

Library of inorganic compounds or materials

The compound or material is a catalyst

The compound or material is metal containing

Alloy

Metal oxide

Library of organic compounds or materials

The compound or material is a carbohydrate or derivative thereof

The compound or material is a nucleotide or a polynucleotide or derivative thereof

The compound or material is a peptide or a polypeptide or derivative thereof

Peptide nucleic acid (i.e., pna)

The compound or material is a polymer

Linking agent for connecting support to library element

Support

Tagging, encoding or labeling agent or material (e.g., microchip transponders, etc.)

Method of making a library

Employing solution phase synthesis not utilizing a support

Using biological means (e.g., using enzyme, microorganism, cell, cellular genetic component, etc.)

Virtual method of making, designing or optimizing a library

Wherein library members are bound to a solid support

Wherein library members are bound to a soluble support

Method of screening a library

Involving a biologically replicable entity (e.g., genetic package, vector, etc.) which is the library, displays the library, contains the library or presents the library

The entity is a microorganism, animal cell or plant cell

Animal cell

Bacteria or protozoa

Yeast or fungus

The entity is a virus or bacteriophage

Screening a library of inorganic compounds or materials

Screening for catalytic activity

The compound or material is metal containing

Alloy

Metal oxide

Screening a library of organic compounds or materials

The compound or material is a carbohydrate or derivative thereof

The compound or material is a nucleotide or a polynucleotide or derivative thereof

The compound or material is a peptide or a polypeptide or derivative thereof

Peptide nucleic acid (i.e., pna)

The compound or material is a polymer

Using deconvolution (e.g., tagging or encoding methodology, etc.)

Virtual/computer based screening method (e.g., using crystallographic coordinates of a target, etc.)

Condition responsive control process

Continuous fermentation

Differentiated tissue or organ other than blood, per se, or differentiated tissue or organ maintaining; composition therefor

Including freezing; composition therefor

Including perfusion; composition therefor

Elimination or reduction of contamination by undersired ferments (e.g., aseptic cultivation)

Enzyme (e.g., ligases (6. ), etc.), proenzyme; compositions thereof; process for preparing, activating, inhibiting, separating, or purifying enzymes

Catalytic antibody

Enzyme inactivation by chemical treatment

Hydrolase (3. )

Acting on carbon to nitrogen bond other than peptide bond (3.5)

Acting on a linear amide linkage in linear amide

Asparaginase

Penicillin amidase

Acting on amide linkage in cyclic amides (e.g., penicillinase, etc.) (3.5.2)

Acting on ester bond (3.1)

Carboxylic ester hydrolase (3.1.1)

Triglyceride splitting (e.g., lipase, etc. (3.1.1.3))

Ribonuclease (3.1.4)

Acting on glycosyl compound (3.2)

Acting on alpha-1, 4-glucosidic bond, (e.g., hyaluronidase, invertase, amylase, etc. (some 3.2.1))

Alpha-amylase, microbial source

Fungal source

Alpha-amylase, plant source (3.2.1.1)

Glucoamylase (3.2.1.3)

Acting on alpha-1, 6-glucosidic bond (e.g., isoamylase, pullulanase, etc.)

Dextranase (3.2.1.11)

Acting on alpha-galatose-glycoside bond (e.g., alpha-galactosidase, etc.)

Acting on beta-1, 4 link between n-acetylmuramic acid and 2-acetylamino 2 deoxy-d-glucose (e.g., lysozyme, etc.)

Acting on beta-1, 4-glucosidic bond (e.g., cellulase, etc. (3.2.1.4))

Acting on beta-galatose-glycoside bond (e.g., beta-galactosidase, etc.)

Acting on peptide bond (e.g., thromboplastin, leucine amino-peptidase, etc., (3.4))

Elastase

Plasmin (i.e., fibrinolysin)

Proteinase

Derived from animal tissue (e.g., rennin, etc.)

Derived from bacteria

Bacteria is bacillus

Bacillus subtilus or bacillus lichenoformis

Derived from fungi

From aspergillus

From yeast

Streptokinase

Thrombin

Trypsin; chymotrypsin

Urokinase

Isomerase (5. )

Glucose isomerase

Lyase (4. )

Malt

Oxidoreductase (1. ) (e.g., luciferase)

Acting on choh group as donor (e.g., glucose oxidase, lactate dehydrogenase (1.1))

Acting on hydrogen peroxide as acceptor (1.11)

Acting on nitrogen-containing compound as donor (1.2, 1.5, 1.7)

Pancreatin

Preparing granular- or free-flowing enzyme composition

Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate

Transferase other than ribonuclease (2.)

Transferring phosphorus containing group (e.g., kineases, etc.(2.7))

Enzyme or microbe electrode

Enzyme separation or purification

By solubility

By sorption

Fermentation vessels in series

Fertility tests

Foam control

Gas detection apparatus

High energy substrates (e.g., fluorescent, chemiluminescent, radioactive, etc.)

Immunohistochemical assay

Including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen, per se

Including enzyme-ligand conjugate production (e.g., reducing rate of nonproductive linkage, etc.)

Incubators or racks or holders for culture plates or containers

Interferon

Involving an enzyme system with high turnover rate or complement magnified assay (e.g., multi-enzyme systems, etc.)

Involving idiotype or anti-idiotype antibody

Kit

Logarithmic growth phase

Maintaining blood or sperm in a physiologically active state or compositions thereof or therefor or methods of in vitro blood cell separation or treatment

Measuring or testing process involving enzymes or micro-organisms; composition or test strip therefore; processes of forming such composition or test strip

Geomicrobiological testing (e.g., for petroleum, etc.)

Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay

Assay in which a label present is an apoenzyme, prosthetic group, or enzyme cofactor

Assay in which a label present is an enzyme inhibitor or functions to alter enzyme activity

Assay in which a label present is an enzyme substrate or substrate analogue

Assay in which an enzyme present is a label

Enzyme produces product which is part of another reaction system (e.g., cyclic reaction, cascade reaction, etc.)

Heterogeneous or solid phase assay system (e.g., elisa, etc.)

Competitive assay

Indirect assay

Sandwich assay

Involving a micro-organism or cell membrane bound antigen or cell membrane bound receptor or cell membrane bound antibody or microbial lysate

Animal cell

Erythrocyte

Leukocyte (e.g., lymphocyte, granulocyte, monocyte, etc.)

Parasite or protozoa

Tumor cell or cancer cell

Bacteria or actinomycetales

Escherichia coli

Salmonella

Sexually transmitted disease (e.g., chlamydia, syphilis, gonorrhea, etc.)

Staphylococcus

Streptococcus

Flagellar-antigen or pili-antigen

Fungi (e.g., yeast, mold, etc.)

Involving a modified enzyme (e.g., abzyme, recombinant, chemically altered, etc.)

Involving avidin-biotin binding

Involving nonmembrane bound receptor binding or protein binding other than antigen-antibody binding

To identify an enzyme or isoenzyme

Involving blood clotting factor (e.g., involving thrombin, thromboplastin, fibrinogen, etc.)

Involving cholesterol

Involving fixed or stabilized, nonliving microorganism, cell, or tissue (e.g., processes of staining, stabilizing, dehydrating, etc.; compositions used therefore, etc.)

Involving a monolayer, smear or suspension of microorganisms or cells

Involving tissue sections

Involving glucose or galactose

Involving hydrolase

Involving amylase

Involving esterase

Involving cholinesterase

Involving phosphatase

Involving peptidase

Involving proteinase

Involving luciferase

Involving nucleic acid

Involving oxidoreductase

Involving catalase

Involving dehydrogenase

Involving peroxidase

Involving transferase

Involving creatine phosphokinase

Involving transaminase

Involving urea or urease

Involving uric acid

Involving viable micro-organism

Determining presence or kind of micro-organism; use of selective media

Enterobacteria

Nitrate to nitrite reducing bacteria

Quantitative determination

Using multifield media

Streptococcus; staphylococcus

Using radioactive material

Methods of sampling or inoculating or spreading a sample; methods of physically isolating an intact micro-organism

Testing for antimicrobial activity of a material

Using multifield media

Testing for sterility condition

Involving virus or bacteriophage

Methods of stopping an enzyme reaction or stabilizing the test materials

Micro-organism cross-reference art collections

Using algae

Using bacteria or actinomycetales

Acetobacter

Achromobacter

Actinomadura

Actinomyces

Actinoplanes

Aerobacter

Alcaligenes

Arthrobacter

Azotobacter

Bacillus

Bacillus brevis

Bacillus cereus

Bacillus circulans

Bacillus licheniformis

Bacillus megaterium

Bacillus polymyxa

Bacillus subtilis

Brevibacterium

Chainia

Clostridium

Corynebacterium

Corynebacterium diphtheriae

Corynebacterium poinsettiae

Corynebacterium pyogenes

Erwinia

Escherichia

Escherichia coli

Flavobacterium

Haemophilus

Klebsiella

Lactobacillus

Lactobacillus acidophilus

Lactobacillus brevis

Lactobacillus casei

Lactobacillus plantarum

Methylomonas

Micrococcus

Micrococcus flavus

Micrococcus glutamicus

Micrococcus lysodeikticus

Micromonospora

Micromonospora chalcea

Micromonospora purpurea

Mycobacterium

Mycobacterium avium

Mycobacterium fortuitum

Mycobacterium smegmatis

Mycoplasma

Neisseria

Nocardia

Proteus

Pseudomonas

Pseudomonas aeruginosa

Pseudomonas fluorescens

Pseudomonas putida

Rhizobium

Salmonella

Serratia

Serratia marcescens

Staphylococcus

Staphylococcus aureus

Staphylococcus epidermidis

Streptococcus

Streptomyces

Streptomyces albus

Streptomyces antibioticus

Streptomyces aureofaciens

Streptomyces aureus

Streptomyces bikiniensia

Streptomyces candidus

Streptomyces chartreusis

Streptomyces diastatochromogenes

Streptomyces filipinensis

Streptomyces fradiae

Streptomyces griseus

Streptomyces hygroscopicus

Streptomyces lavendulae

Streptomyces lincolnensis

Streptomyces noursei

Streptomyces olivaceus

Streptomyces platensis

Streptomyces rimosus

Streptomyces sparogenes

Streptomyces venezuelae

Streptosporangium

Streptovirticillium

Vibrio

Xanthomonas

Using fungi

Absidia

Aspergillus

Aspergillus awamori

Aspergillus flavus

Aspergillus fumigatus

Aspergillus niger

Aspergillus oryzae

Aspergillus ustus

Aspergillus wenti

Candida

Candida albicans

Candida lipolytica

Candida tropicalis

Cephalosporium

Cephalosporium acremonium

Cephalosporium caerulens

Cephalosporium crotocinigenium

Fusarium

Hansenula

Mucor

Paecilomyces

Penicillium

Penicillium brevi

Penicillium chrysogenum

Penicillium notatium

Penicillium patulum

Pichia

Rhizopus

Saccharomyces

Saccharomyces carlsbergensis

Saccharomyces cerevisiae

Saccharomyces lactis

Torulopsis

Trichoderma

Using protozoa

Using viruses or cell lines

Micro-organism, per se (e.g., protozoa, etc.); compositions thereof; proces of propagating, maintaining or preserving micro-organisms or compositions thereof; process of preparing or isolating a composition containing a micro-organism; culture media therefor

Adaptation or attenuation of cells

Algae, media therefor

Chlamydomonas

Chlorella

Euglena

Scenedesmus

Transformants

Bacteria or actinomycetales; media therefor

Actinoplanes

Bacillus (e.g., b. subtilis, b. thuringiensis, etc.)

Clostridium

Culture media, per se

Escherichia (e.g., e. coli, etc.) or salmonella

Lactobacillus, pediococcus, or leuconostoc

Mixed culture

Mycobacterium

Nocardia

Pseudomonas

Rhizobium or agrobacterium

Streptococcus

Streptomyces

Transformants (e.g., recombinant dna or vector or foreign or exogenous gene containing, fused bacteria, etc.)

Bacillus (e.g., b. subtilis, b. thuringiensis, etc.)

Brevibacterium or corynebacterium

Escherichia (e.g., e. coli, etc.)

Pseudomonas

Streptomyces

Chemical stimulation of growth or activity by addition of chemical compound which is not an essential growth factor; stimulation of growth by removal of a chemical compound

Foam culture

Fungi

Aspergillus

Cephalosporium or acremonium

Culture media, per se, or technique

Fusarium

Mucor

Penicillium

Rhizopus

Transformants

Aspergillus

Fusarium

Mucor

Neurospora

Penicillium

Rhizopus

Trichoderma

Yeast; media therefor

Candida

Pichia

Saccharomyces

Trichoderma

Yeast

Candida or torulopsis

Cryptococcus

Culture media, per se, or technique

Hansenula

Pichia

Saccharomyces

Culture media, per se, or technique

Lysis of micro-organism

Preserving or maintaining micro-organism

Protozoa, media therefor

Eimeria

Leishmania

Plasmodium

Separation of micro-organism from culture media

Utilizing media containing cellulose or hydrolysates thereof

Utilizing media containing hydrocarbon

Aliphatic

Having five or less carbon atoms

Utilizing media containing lower alkanol (i.e., having one to six carbon atoms)

Utilizing media containing waste sulphite liquor

Micro-organism, tissue cell culture or enzyme using process to synthesize a desired chemical compound or composition

Enzymatic production of a protein or polypeptide (e.g., enzymatic hydrolysis, etc.)

Preparing alpha or beta amino acid or substituted amino acid or salts thereof

Alanine; leucine; isoleucine; serine; homoserine

Aspartic acid (asparaginic acid); asparagine

Citrulline; arginine; ornithine

Glutamic acid; glutamine

Utilizing biotin or its derivatives

Utilizing surfactant fatty acids or fatty acid esters (i.e., having seven or more atoms)

Lysine; diaminopimelic acid; threonine; valine

Methionine; cysteine; cystine

Proline; hydroxyproline; histidine

Tryptophan; tyrosine; phenylalanine; 3,4 dihydroxyphenylalanine

Preparing compound containing a carotene nucleus (i.e., carotene)

Preparing compound containing a cyclopentanohydrophenanthrene nucleus; nor-, homo-, or d-ring lactone derivatives thereof

Acting on d-ring

Acting at 17-position

Hydroxylating at 17-position

Hydroxylating at 16-position

Containing heterocyclic ring

Dehydrogenating; dehydroxylating

Forming an aryl ring from "a" ring

Hydroxylating

At 11-position

At 11 alpha position

Preparing compound containing a prostaglandin nucleus

Preparing compound containing at least three carbocyclic rings

Preparing compound containing saccharide radical

Disaccharide

Mashing or wort making

Monosaccharide

Polysaccharide of more than five saccharide radicals attached to each other by glycosidic bonds

Dextran

Pullulan

Xanthan; i.e., xanthomonas-type heteropolysaccharides

Preparing nitrogen-containing saccharide

N-glycoside

Cobalamin (i.e., vitamin b12, lld factor)

Nucleoside

Having a fused ring containing a six-membered ring having two n-atoms in the same ring (e.g., purine nucleosides, etc.)

Nucleotide

Dinucleotide (e.g., nad, etc.)

Having a fused ring containing a six-membered ring having two n-atoms in the same ring (e.g., purine based mononucleotides, etc.)

Polynucleotide (e.g., nucleic acid, oligonucleotide, etc.)

Acellular exponential or geometric amplification (e.g., pcr, etc.)

Involving the making of multiple rna copies

Acellular preparation of polynucleotide

Involving a hydrolase (3.)

Involving a ligase (6.)

Involving rna as a starting material or intermediate

Modification or preparation of a recombinant dna vector

By insertion or addition of one or more nucleotides

Involving deletion of a nucleotide or nucleotides from a vector

Polynucleotide contains only ribonucleotide monomers

Involving catalytic ribonucleic acid

Prepared from virus, prokaryotic acid

Involving virus

Preparing o-glycoside (e.g., glucosides, etc.)

Oxygen atom of the saccharide radical is bonded to a cyclohexyl radical (e.g., kasugamycin, etc.)

Cyclohexyl radical is substituted by two or more nitrogen atoms (e.g., destomycin, neamin, etc.)

Cyclohexyl radical is attached directly to a nitrogen atom of two or more n-c(=n)-n radicals (e.g., streptomycin, etc.)

Having two saccharide radicals bonded through only oxygen to adjacent ring carbons of the cyclohexyl radical (e.g., ambutyrosin, ribostamycin, etc.)

Containing three or more saccharide radicals (e.g., liquidomycin, neomycin, lividomycin, etc.)

Oxygen atom of the saccharide radical is directly bonded to a condensed ring system having three or more carboxyclic rings (e.g., dauomycin, adriamycin, etc.)

Oxygen atom of the saccharide radical is directly linked through only acyclic carbon atoms to a nonsaccharide heterocyclic ring (e.g., bleomycin, phleomycin, etc.)

Oxygen of the saccharide radical is directly bonded to a nonsaccharide heterocyclic ring or a fused- or bridged-ring system which contains a nonsaccharide heterocyclic ring (e.g., coumermycin, novobiocin, etc.)

The hetero ring has eight or more ring members and only oxygen as ring hetero atoms (e.g., erythromycin, spiramycin, nystatin, etc.)

Preparing s-glycoside (e.g., lincomycin, etc.)

Produced by the action of a beta-amylase (e.g., maltose by the action of beta-amylase on amylose, etc.)

Produced by the action of a carbohydrase (e.g., maltose by the action of alpha amylase on starch, etc.)

Produced by the action of a glycosyl transferase (e.g., alpha, beta, gamma-cyclodextrins by the action of glycosyl transferase on starch, etc.)

Produced by the action of an alpha-1, 6-glucosidase (e.g., amylose debranched amylopectin by the action of pullulanase, etc.)

Produced by the action of an exo-1.4 alpha glucosidase (e.g., dextrose by the action of glucoamylase on starch, etc.)

Produced by the action of an isomerase (e.g., fructose by the action of xylose isomerase on glucose, etc.)

Preparing compound having a 1-thia-4-aza-bicyclo (3.2.0) heptane ring system (e.g., penicillin, etc.)

By acylation of the substituent in 6-position

By desacylation of the substituent in 6-position

In presence of phenyl acetic acid or phenyl acetamide or their derivatives

Preparing compound having a 1-thia-5-aza-bicyclo (4.2.0) octane ring system (e.g., cephalosporin, etc.)

By acylation of the substituent in the 7-position

By desacylation of the substituent in the 7-position

Cephalosporin c

Di-substituted in 7-position

Preparing compound other than saccharide containing a gibberellin nucleus (i.e., gibbane)

Preparing compound other than saccharide containing a tetracycline nucleus (e.g., naphacene, etc.)

Preparing compound other than saccharide containing alloxazine or isoalloxazine nucleus

Preparing element or inorganic compound except carbon dioxide

Preparing heterocyclic carbon compound having only o, n, s, se, or te as ring hetero atoms

Containing two or more hetero rings

Containing at least two hetero rings bridged or fused among themselves or bridged or fused with a common carbocyclic ring system, (e.g., rifamycin, etc.)

Nitrogen as only ring hetero atom

Containing six-membered hetero ring

Nitrogen or oxygen hetero atom and at least one other diverse hetero ring atom in the same ring

Oxygen as only ring hetero atom

Containing a hetero ring of at least seven ring members (e.g., zearalenone, macrocyclic lactones, etc.)

Containing five-membered hetero ring (e.g., griseofulvin, etc.)

Containing six-membered hetero ring (e.g., fluorescein, etc.)

Preparing hydrocarbon

Only acyclic

Preparing nitrogen-containing organic compound

Amide (e.g., chloramphenicol, etc.)

Preparing organic compound containing a metal or atom other than h, n, c, o, or halogen

Preparing oxygen-containing organic compound

Carboxylic acid ester

Containing a carboxyl group

Acetic acid

Hydroxy carboxylic acid

Lactic acid

Polycarboxylic acid

Dicarboxylic acid having four or less carbon atoms (e.g., fumaric, maleic, etc.)

Having keto group (e.g., alpha-ketoglutaric acid, etc.)

Tricarboxylic acid (e.g., citric acid, etc.)

Propionic or butyric acid

Sugar acid having five or more carbon atoms (i.e., aldonic, keto-aldonic, or saccharic acid)

Alpha-ketogulonic acid (i.e., 2-ketogulonic acid)

Containing carbonyl group

Ketone

Acetone containing product

Substrate contains grain or cereal material

Substrate contains inorganic compound, other than water

Substrate contains inorganic nitrogen source

Substrate contains protein as nitrogen source

Cyclopentanone or cyclopentadione containing compound

Containing hydroxy group

Acyclic

Butanol

Ethanol

Multiple stages of fermentation; multiple types of micro-organisms or reuse of micro-organisms

Produced as by-product, or from waste, or from cellulosic material substrate

Substrate contains cellulosic material

Substrate contains sulphite waste liquor or citrus waste

Polyhydric

Glycerol

Aromatic

Containing quinone nucleus (i.e., quinoid structure)

Fat; fatty oil; ester-type wax; higher fatty acid (i.e., having at least seven carbon atoms in an unbroken chain bound to a carboxyl group); oxidized oil or fat

Preparing sulfur-containing organic compound

Process involving micro-organisms of different genera in the same process, simultaneously

Recombinant dna technique included in method of making a protein or polypeptide

Antigens

Blood proteins

Enzyme inhibitors or activators

Fusion proteins or polypeptides

Hormones and fragments thereof

Lymphokines or monokines

Interferons

Interleukins

Signal sequence (e.g., beta-galactosidase, etc.)

Yeast derived

Using a micro-organism to make a protein or polypeptide

Procaryotic micro-organism

Antibiotic or toxin

Using actinomycetales

Using bacteria

Using fungi

Using tissue cell culture to make a protein or polypeptide

Animal tissue cell culture

Blood (lymphoid) cell culture

Producing interferons

Fused or hybrid cells

Producing monoclonal antibody

Micro-organisms used in the destruction of hazardous or toxic waste

Miscellaneous (e.g., subcellular parts of micro-organisms, etc.)

Modified antibody (e.g., hybrid, bifunctional, etc.)

Multiple layering of reactants

Optical sensing apparatus

Packaged device or kit

Physical recovery methods (e.g., chromatography, grinding)

Plant cell or cell line, per se (e.g., transgenic, mutant, etc.); composition thereof; process of propagating, maintaining, or preserving plant cell or cell line; process of isolating or separating a plant cell or cell line; process of regenerating plant cells into tissue, plant part, or plant, per se, where no genotypic change occurs; medium therefore

Corn cell or cell line, per se

Herbicide resistant

Culture, maintenance, or preservation techniques, per se

Involving conifer cell or tissue (e.g., pine, spruce, fir, cedar, etc.)

Involving corn cell or tissue

Involving cotton cell or tissue

Involving potato cell or tissue

Involving protoplast

Involving regeneration or propagation into a plant or plant part

Involving callus or embryonic stage

Involving soybean cell or tissue

Involving sunflower cell or tissue

Involving tobacco cell or tissue

Involving tomato cell or tissue

Medium, per se, for culture, maintenance, regeneration, etc.

Plant cell or cell line, per se, contains exogenous or foreign nucleic acid

Plant cell or cell line, per se, is pest or herbicide resistant or pest lethal

Potato cell or cell line, per se

Soybean cell or cell line, per se

Sunflower cell or cell line, per se

Tobacco cell or cell line, per se

Tomato cell or cell line, per se

Prevention or removal of interfering materials or reactants or other treatment to enhance results (e.g., determining or preventing nonspecific binding, etc.)

Process of mutation, cell fusion, or genetic modification

Fusion of cells

Employing electric current

One of the fusing cells is a human antibody-producing cell

One of the fusing cells is a microorganism (e.g., prokaryote, fungus, etc.)

One of the fusing cells is a mouse antibody-producing cell

One of the fusing cells is a plant cell

Introduction of a polynucleotide molecule into or rearrangement of a nucleic acid within a plant cell

Introduction via agrobacterium

Introduction via electroporation, particle, fiber or microprojectile mediated insertion, or injection

Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within a microorganism (e.g., bacteria, protozoa, bacteriophage, etc.)

The polynucleotide contains a transposon

The polynucleotide is a cosmid

The polynucleotide is a plasmid or episome

Microorganism of the genus bacillus is a host for the plasmid or episome

Microorganism of the genus brevibacterium or the genus corynebacterium is a host for the plasmid or episome

Microorganism of the genus escherichia is a host for the plasmid or episome

Microorganism of the genus streptomyces is a host for the plasmid or episome

Mycelial fungus is a host for the plasmid or episome

Plasmid or episome confers the ability to utilize directly a compound which a wild type microorganism is unable to utilize

Plasmid or episome contains a gene which complements a nutritional deficiency mutation

Plasmid or episome contains a gene which confers resistance to metal, silicon, selenium, or tellurium toxicity

Plasmid or episome contains at least part of a gene encoding a restriction endonuclease or modification enzyme

Plasmid or episome contains at least part of a gene encoding a toxin or encoding for virulence or pathogenicity

Plasmid or episome contains dna targeting homologous recombination to bacteriophage, viral, or chromosomal dna within a microorganism

Plural nonidentical plasmids are introduced into a host microorganism or culture thereof (e.g., plasmid is part of a library, etc.)

Yeast is a host for the plasmid or episome

The polynucleotide is an unbranched linear fragment

The polynucleotide is encapsidated within a bacteriophage, bacteriophage coat, or transducing particle

The polynucleotide is unencapsidated bacteriophage or viral nucleic acid

Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell

Introducing an oncogene to establish a cell line

Involving co-transfection

Involving electroporation

Involving gene duplication within the cell (e.g., amplification, co-amplification, etc.)

Involving general or homologous recombination (e.g., gene targeting, etc.)

Involving laser treatment of the cell before or during transfection

Involving particle-mediated transfection (i.e., biolistic transfection)

Involving site-specific recombination (e.g., cre-lox, etc.)

The polynucleotide is a shuttle vector or a transiently replicating hybrid vector

The polynucleotide is coated with or encapsulated within a lipid containing material (e.g., liposome, etc.)

The polynucleotide is encapsidated within a virus or viral coat

Helper virus is present

Mutation employing a chemical mutagenic agent

By replacement of standard nucleic acid base with base analog (e.g., 5-bromouracil, etc.)

By use of alkylating agent (e.g., nitrosoguanidine, etc.)

By use of intercalating agent (e.g., acridine orange, etc.)

By use of oxidative deamination agent (e.g., nitrous acid, etc.)

Mutation employing radiation or electricity

Ultraviolet irradiation

X-ray irradiation

Process of utilizing an enzyme or micro-organism to destroy hazardous or toxic waste, liberate, separate, or purify a preexisting compound or composition therefore; cleaning objects or textiles

Cleaning using a micro-organism or enzyme

Depilating hides, bating, or hide treating using enzyme or micro-organism

Destruction of hazardous or toxic waste

Petroleum oil or shale oil treating

Desulfurizing

Resolution of optical isomers or purification of organic compounds or composition containing same

Textile treating

Treating animal or plant material or micro-organism

Carbohydrate material recovered or purified

Cellulose (e.g., plant fibers, etc.)

Hemp or flax treating

Producing paper pulp

Pectin or starch

Sugar (e.g., molasses treatment, etc.)

Glyceridic oil, fat, ester-type wax, or higher fatty acid recovered or purified

Proteinaceous material recovered or purified

Collagen or gelatin

Removing nucleic acid from intact or disrupted cell

Treating blood fraction

Treating organ or animal secretion

Treating gas, emulsion, or foam

Related to subclasses

Simultaneous determination of more than one analyte

Single cell protein

Spore forming or isolating process

Standards, controls, materials (e.g., validation studies, buffer systems, etc.)

Subcellular parts of micro-organisms

Test papers

Test strip or test slide

Treatment of micro-organisms or enzymes with electrical or wave energy (e.g., magnetism, sonic waves, etc.)

Cell membrane or cell surface is target

Lytic effect produced (e.g., disruption of cell membrane for release of subcellular parts; e.g., nucleic acids, etc.)

Membrane permeability increased

Electroporation

Concentration, separation, or purification of micro-organisms

Enzyme treated

Metabolism of micro-organism enhanced (e.g., growth enhancement or increased production of microbial product)

Modification of viruses (e.g., attenuation, etc.)

Vector, per se (e.g., plasmid, hybrid plasmid, cosmid, viral vector, bacteriophage vector, etc.) bacteriophage vector, etc.)

Virus or bacteriophage, except for viral vector or bacteriophage vector; composition thereof; preparation or purification thereof; production of viral subunits; media for propagating

Inactivation or attenuation; producing viral subunits

By chemical treatment

By serial passage of virus

Recovery or purification