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Class Information
Number: 424/94.67
Name: Drug, bio-affecting and body treating compositions > Enzyme or coenzyme containing > Hydrolases (3. ) (e.g., urease, lipase, asparaginase, muramidase, etc.) > Acting on peptide bonds (3.4) (e.g., urokinease, etc.) > Metalloproteinases (3.4.24) (e.g., collagenase, snake venom zinc proteinase, etc.)
Description: Subject matter which contain enzymes with the Enzyme Commission classification of 3.4.24.










Patents under this class:
1 2 3

Patent Number Title Of Patent Date Issued
8703429 Composition exhibiting a von Willebrand Factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV Apr. 22, 2014
8703128 Methods of modulating TGF.beta. signaling Apr. 22, 2014
8703426 Composition exhibiting a von Willebrand Factor (vWF) protease activity with the amino acid sequence AAGGILHLELLV Apr. 22, 2014
8679521 Treatment of ophthalmic conditions Mar. 25, 2014
8623352 Stabilized liquid and lyophilized ADAMTS13 formulations Jan. 7, 2014
8617543 Modified mutant collagenase and its use in fat melting and in scar reduction Dec. 31, 2013
8591884 Compositions and methods for enhancing metal ion dependent drug therapies Nov. 26, 2013
8580553 Phage-associated lytic enzymes for treatment of Bacillus anthracis and related conditions Nov. 12, 2013
8580250 Botulinum toxin compositions Nov. 12, 2013
8524226 Methods of prolonging patency of hemodialysis access Sep. 3, 2013
8475831 Treatment of ophthalmic conditions Jul. 2, 2013
8394373 ADAMTS13 genes and proteins and variants, and therapeutic compositions and methods of utilizing the same Mar. 12, 2013
8388952 Botulinum toxin compositions and methods Mar. 5, 2013
8383103 Botulinum toxin compositions and methods Feb. 26, 2013
8337836 Methods for the treatment and prevention of diseases of biological conduits Dec. 25, 2012
8329159 Hepatitis C virus inhibitors Dec. 11, 2012
8323643 Methods for treating adhesive capsulitis Dec. 4, 2012
8323642 Tissue fusion method using collagenase for repair of soft tissue Dec. 4, 2012
8309341 2-mercaptocyclopentanecarboxylic acid compounds, a process for their preparation and pharmaceutical compositions containing them Nov. 13, 2012
8158132 Clostridial toxin derivatives able to modify peripheral sensory afferent functions Apr. 17, 2012
8142801 Pesticidal compositions and methods of use thereof Mar. 27, 2012
8021660 Use of collagenase to facilitate guide wire crossing in total arterial occlusions Sep. 20, 2011
8012471 Screening and treatment methods using IGS5 enzymes of the metalloprotease family Sep. 6, 2011
7943128 Anti-microbial compositions comprising a cationic peptide and a glycylglycine endopeptidase May. 17, 2011
7935337 Method of therapy for degenerative intervertebral discs May. 3, 2011
7910094 Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV Mar. 22, 2011
7897147 Treatment of premenstrual disorders Mar. 1, 2011
7883699 Methods for enlarging the lumen of an obstructed biological conduit Feb. 8, 2011
7867747 Fibrinolytic metalloprotease and composition comprising the same Jan. 11, 2011
7854929 Method for treating lateral epicondylitis using collagenase Dec. 21, 2010
7833524 Method of preparing botulinum neurotoxin type E light chain Nov. 16, 2010
7824673 Reduction of adipose tissue Nov. 2, 2010
7811560 Compositions and methods for treating collagen-mediated diseases Oct. 12, 2010
7641900 Wound treatment utilizing collagenase and a phosphotidylcholine organogel Jan. 5, 2010
7550282 Biological glue based on thrombin-conjugated nanoparticles Jun. 23, 2009
7517522 ADAMTS13 genes and proteins and variants and therapeutic compositions and methods utilizing the same Apr. 14, 2009
7501117 Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV Mar. 10, 2009
7452543 Conjugates of galactose-binding lectins and clostridial neurotoxins as analgesics Nov. 18, 2008
7429377 Therapeutic composition containing a plurality of immobilized proteases Sep. 30, 2008
7425326 Use of collagenase to facilitate guide wire crossing in total arterial occlusions Sep. 16, 2008
7402309 Phage-associated lytic enzymes for treatment of Bacillus anthracis and related conditions Jul. 22, 2008
7399466 Method and compositions for promoting osteogenesis Jul. 15, 2008
7311908 Pharmaceutical compositions of fibrinolytic agent Dec. 25, 2007
RE39941 Amelioration of Dupuytren's disease Dec. 18, 2007
7252820 Highly purified mocarhagin, a cobra venom protease, polynucleotides encoding same and related proteases, and therapeutic uses thereof Aug. 7, 2007
7244426 Pharmaceutical compositions of fibrinolytic agent Jul. 17, 2007
7208150 Analgesic from snake venom Apr. 24, 2007
7141610 Compositions and methods for the induction of retinal detachments Nov. 28, 2006
7138114 Pharmaceutical compositions of fibrinolytic agent Nov. 21, 2006
7083964 Method for purifying enzymes from clostridium histolyticum using multi-stage chromatography Aug. 1, 2006

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