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Class Information
Number: 424/94.3
Name: Drug, bio-affecting and body treating compositions > Enzyme or coenzyme containing > Stabilized enzymes or enzymes complexed with nonenzyme (e.g., liposomes, etc.)
Description: Subject matter in which (a) the enzyme is contacted with an extraneous material to impart to the enzyme a resistance to loss of activity, or (b) the enzyme is reacted with a nonenzymatic material to form a complex or a chemically modified enzymatic compound; e.g., conjugate, ligand, etc.










Patents under this class:
1 2 3 4 5 6 7 8

Patent Number Title Of Patent Date Issued
8647620 Chimeric factor VII molecules Feb. 11, 2014
8637007 Factor VIIa-polysialic acid conjugate having prolonged in vivo half-life Jan. 28, 2014
8632770 Glycopegylated factor IX Jan. 21, 2014
8597641 Instant enzyme formulations for animal nutrition Dec. 3, 2013
8580250 Botulinum toxin compositions Nov. 12, 2013
8574569 Stabilized protease composition Nov. 5, 2013
8568708 Tumor-specific delivery of therapeutic agents via liposomase Oct. 29, 2013
8545837 Methods and compositions for CNS delivery of iduronate-2-sulfatase Oct. 1, 2013
8518409 System for selective cell treatment using ideotypically modulated pharmacoeffectors Aug. 27, 2013
8486388 Protein formulation Jul. 16, 2013
8486399 Methods and compositions for increasing arylsulfatase A activity in the CNS Jul. 16, 2013
8481040 Carrier for targeting nerve cells Jul. 9, 2013
8465734 Methods for increasing protein polyethylene glycol (PEG) conjugation Jun. 18, 2013
8449979 Molecular aggregate capable of undergoing phase transition by dehydrating condensation and method of phase transition thereof May. 28, 2013
8449880 Chemical modification of proteins for their more accurate molecular-weight determination by electrophoresis May. 28, 2013
8444963 Tumor specific delivery of therapeutic agents via liposomase May. 21, 2013
8440183 Angiogenin complexes (ANGex) with lipid-based substrates and uses thereof May. 14, 2013
8431121 Specifically targeted catalytic antagonists and uses thereof Apr. 30, 2013
8426220 Utilization of shield effect for dopamine detection and reagent development Apr. 23, 2013
8394372 Stabilized protease composition Mar. 12, 2013
8383102 Fusion of peptidoglycan hydrolase enzymes to a protein transduction domain allows eradication of both extracellular and intracellular gram positive pathogens Feb. 26, 2013
8383380 Segmented polymers and their conjugates Feb. 26, 2013
8361442 Oxime conjugates and methods for their formation and use Jan. 29, 2013
8349318 Use of specifically engineered enzymes to enhance the efficacy of prodrugs Jan. 8, 2013
8343487 Large-scale production of soluble hyaluronidase Jan. 1, 2013
8333962 Controlled release multidrug formulations for spinal cord injury Dec. 18, 2012
8318466 Process for immobilization of protein catalysts, product, and use Nov. 27, 2012
8293228 Variant form of urate oxidase and use thereof Oct. 23, 2012
8293231 Methods and compositions for treating ischemia Oct. 23, 2012
8293710 Method for treating wounds using an EGF-like domain of thrombomodulin Oct. 23, 2012
8273376 Colonic delivery of metallo-dependent enzymes Sep. 25, 2012
8188224 Variant forms of urate oxidase and use thereof May. 29, 2012
8168415 Axl fusion proteins as Axl tyrosine kinase inhibitors May. 1, 2012
8124073 Targeting of glycoprotein therapeutics Feb. 28, 2012
8110218 Compositions and methods for less immunogenic protein-lipid complexes Feb. 7, 2012
8110386 Lipase powder, methods for producing the same and use thereof Feb. 7, 2012
8067217 Method for preserving reduced coenzyme Q10 Nov. 29, 2011
8017739 Conjugates of hydroxyalkyl starch and a protein Sep. 13, 2011
7932225 Glue composition for lung volume reduction Apr. 26, 2011
7927589 PEG-urate oxidase conjugates and use thereof Apr. 19, 2011
7927622 Methods of transnasal transport/immunization with highly adaptable carriers Apr. 19, 2011
7914781 Compositions for inhibiting atherosclerosis Mar. 29, 2011
7892536 Storage-stable glucose oxidase Feb. 22, 2011
7833765 Galenic formulation for colon-targeted delivery of active ingredients Nov. 16, 2010
7803367 Methods and compositions for promoting angiogenesis Sep. 28, 2010
7799549 Methods for increasing protein polyethylene glycol (PEG) conjugation Sep. 21, 2010
7700336 Lecithinized superoxide dismutase composition and a process for its production Apr. 20, 2010
7678767 Glue compositions for lung volume reduction Mar. 16, 2010
7670605 Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds Mar. 2, 2010
7658917 Modulators of amyloid aggregation Feb. 9, 2010

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