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Class Information
Number: 424/469
Name: Drug, bio-affecting and body treating compositions > Preparations characterized by special physical form > Tablets, lozenges, or pills > Sustained or differential release type > Discrete particles in supporting matrix
Description: Subject matter in which discrete soluble particles of the active ingredient are positioned or dispersed in a solid, generally insoluble matrix from which said particles are leached sequentially under conditions of use from the outside portions of the matrix inwardly.


Sub-classes under this class:

Class Number Class Name Patents
424/470 Where particles are granulated 504


Patents under this class:
1 2 3 4 5 6 7 8 9 10 11 12

Patent Number Title Of Patent Date Issued
6528094 Stable shaped particles of crystalline organic compounds Mar. 4, 2003
6524618 Directly compressible extended-release matrix formulation for metformin hydrochloride Feb. 25, 2003
6521261 Pharmaceutical excipient having improved compressibility Feb. 18, 2003
6517866 Sertraline salts and sustained-release dosage forms of sertraline Feb. 11, 2003
6517868 Amino acid modulated extended release dosage form Feb. 11, 2003
6514531 Controlled-release dosage forms comprising zolpidem or a salt thereof Feb. 4, 2003
6500457 Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent Dec. 31, 2002
6492488 Controlled release polyacrylic acid granules and a process for preparing the same Dec. 10, 2002
6488962 Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms Dec. 3, 2002
6485743 Method and composition of an oral preparation of itraconazole Nov. 26, 2002
6485759 Botanical combinations for treating AIDS and immune-deficient patients to maintain good health and the process for preparing the same Nov. 26, 2002
6482434 Method for reducing adverse effects of a weight loss regimen Nov. 19, 2002
6475521 Biphasic controlled release delivery system for high solubility pharmaceuticals and method Nov. 5, 2002
6468959 Peroral dosage form for peptide containing medicaments, in particular insulin Oct. 22, 2002
6468976 Monohydrate lisinopril Oct. 22, 2002
6462022 Lisinopril compositions having large-particle DCPD Oct. 8, 2002
6451345 Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration Sep. 17, 2002
6419960 Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations Jul. 16, 2002
6419952 Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings Jul. 16, 2002
6414050 Biofunctional polymers prepared in supercritical fluid Jul. 2, 2002
6399096 Pharmaceutical formulation Jun. 4, 2002
6399100 Controlled release pharmaceutical compositions containing tiagabine Jun. 4, 2002
6391338 System for rendering substantially non-dissoluble bio-affecting agents bio-available May. 21, 2002
6372255 Tablet for instant and prolonged release of one or more active substances Apr. 16, 2002
6365184 Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a NSAID Apr. 2, 2002
6365180 Oral liquid compositions Apr. 2, 2002
6365185 Self-destructing, controlled release peroral drug delivery system Apr. 2, 2002
6358531 Method for preparing porous shells or gels from glass particles Mar. 19, 2002
6358533 Pharmaceutical excipient having improved compressibility Mar. 19, 2002
6352722 Derivatized carbohydrates, compositions comprised thereof and methods of use thereof Mar. 5, 2002
6348216 Ibuprofen and narcotic analgesic compositions Feb. 19, 2002
6340476 Pharmaceutical dosage form for pulsatile delivery of methylphenidate Jan. 22, 2002
6340475 Extending the duration of drug release within the stomach during the fed mode Jan. 22, 2002
6338857 Sustained release carbamazepine pharmaceutical composition free of food effect and a method for alleviating food effect in drug release Jan. 15, 2002
6319518 Colon selective drug delivery composition Nov. 20, 2001
6306439 Expandable pharmaceutical forms Oct. 23, 2001
6306438 Stabilized sustained release tramadol formulations Oct. 23, 2001
6306427 Pellets containing active ingredients protected against degradation in the rumen of ruminants Oct. 23, 2001
6296842 Process for the preparation of polymer-based sustained release compositions Oct. 2, 2001
6296873 Zero-order sustained release delivery system for carbamazephine derivatives Oct. 2, 2001
6294201 Osmotic medicament releasing system Sep. 25, 2001
6287693 Stable shaped particles of crystalline organic compounds Sep. 11, 2001
6284273 Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds Sep. 4, 2001
6280771 Dosage forms exhibiting multi-phasic release kinetics and methods of manufacture thereof Aug. 28, 2001
6277406 Easily processed tablet compositions Aug. 21, 2001
6277405 Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it Aug. 21, 2001
6274174 Aggregates of spherical multivalent metal alginate microparticles and methods of making them Aug. 14, 2001
6270797 Sustained release pharmaceutical composition containing glipizide and method for producing same Aug. 7, 2001
6267986 Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine Jul. 31, 2001
6261601 Orally administered controlled drug delivery system providing temporal and spatial control Jul. 17, 2001

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