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Class Information
Number: 424/183.1
Name: Drug, bio-affecting and body treating compositions > Conjugate or complex of monoclonal or polyclonal antibody, immunoglobulin, or fragment thereof with nonimmunoglobulin material > Conjugated to proteinaceous toxin or fragment thereof (e.g., conjugated to diphtheria toxin, pseudomonas exotoxin, ricin, gelonin, abrin, etc.)
Description: Subject matter wherein the nonimmunoglobulin material is a proteinaceous toxin or fragment thereof.










Patents under this class:
1 2 3 4 5 6 7 8 9

Patent Number Title Of Patent Date Issued
8703143 Antibodies of the ED-B domain of fibronectin, their construction and uses Apr. 22, 2014
8663642 Anti-CD70 antibody-drug conjugates and their use for the treatment and prevention of cancer and immune disorders Mar. 4, 2014
8637012 Genetic products differentially expressed in tumors and the use thereof Jan. 28, 2014
8637027 Anti c-Met antibodies Jan. 28, 2014
8617556 Gram-positive bacteria specific binding compounds Dec. 31, 2013
8613903 Humanized L243 antibodies Dec. 24, 2013
8609105 Auristatin drug linker conjugates Dec. 17, 2013
8597655 Recombinant fusion protein and polynucleotide construct for immunotoxin production Dec. 3, 2013
8586047 Genetic products differentially expressed in tumors and the use thereof Nov. 19, 2013
8586714 Dual variable domain immunoglobulins and uses thereof Nov. 19, 2013
8562989 Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer Oct. 22, 2013
8545850 Anti-CD79B antibodies and immunoconjugates and methods of use Oct. 1, 2013
8540998 Methods for treating cancer using ephrin type-A receptor 10 antibodies conjugated to cytotoxic agents Sep. 24, 2013
8524241 Fusion proteins comprising a fragment of Vibrio cholerae exotoxin A Sep. 3, 2013
8524240 Diagnosis and therapy of hematological malignancies Sep. 3, 2013
8524238 Cancer targets and uses thereof Sep. 3, 2013
8518409 System for selective cell treatment using ideotypically modulated pharmacoeffectors Aug. 27, 2013
8470330 PSMA antibodies and uses thereof Jun. 25, 2013
8460661 Methods of using antibodies that bind the glutamate ligand binding region of Notch1 Jun. 11, 2013
8444990 Antibody-induced apoptosis May. 21, 2013
8440195 Inhibition of CD69 for treatment of inflammatory conditions May. 14, 2013
8420094 Fusion proteins comprising a fragment of Vibrio cholerae exotoxin A Apr. 16, 2013
8398982 Compositions and methods for the diagnosis and treatment of tumor Mar. 19, 2013
8394382 Siglec-9 Binding Agents Mar. 12, 2013
8388973 Compositions and methods for the treatment of tumor of hematopoietic origin Mar. 5, 2013
8383123 Method of treatment targeting HEPSIN Feb. 26, 2013
8383122 Process for preparing purified drug conjugates Feb. 26, 2013
8383117 CD44E tumor specific antibody Feb. 26, 2013
8367066 Antiviral bifunctional molecules, methods of construction and methods of treating virus-induced cancer therewith Feb. 5, 2013
8333971 Methods and compositions for treatment of human immunodeficiency virus infection with conjugated antibodies or antibody fragments Dec. 18, 2012
8329183 Recombinant fusion protein and polynucleotide construct for immunotoxin production Dec. 11, 2012
8278423 Monoclonal antibodies and fragment thereof directed against the human Anti-Mullerian Hormone type II receptor (AMHR-II) Oct. 2, 2012
8268309 Compositions and methods for the therapy and diagnosis of cytomegalovirus Sep. 18, 2012
8263041 Antigen associated with the neovasculature of tumour metastases Sep. 11, 2012
8263083 Combination therapy with antibody-drug conjugates Sep. 11, 2012
8263744 Binding proteins that bind to EpCAM linked to an effector molecule Sep. 11, 2012
8258268 Dual variable domain immunoglobulin and uses thereof Sep. 4, 2012
8257708 Antibodies against cancer antigen TMEFF2 and uses thereof Sep. 4, 2012
8226945 Antibodies and immunoconjugates and uses therefor Jul. 24, 2012
8216584 Imaging, diagnosis and treatment of disease Jul. 10, 2012
8211440 Multivalent immunoglobulin-based bioactive assemblies Jul. 3, 2012
8198416 Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen Jun. 12, 2012
8158128 Monoclonal antibodies to progastrin Apr. 17, 2012
8124094 Immunoglobulin Fc fragment modified by non-peptide polymer and pharmaceutical composition comprising the same Feb. 28, 2012
8105596 Immunotherapy of B-cell malignancies using anti-CD22 antibodies Jan. 31, 2012
8092809 Pseudomonas exotoxin A-like chimeric immunogens Jan. 10, 2012
8084029 Alpha-fetoprotein Immu31 antibodies and fusion proteins and methods of use thereof Dec. 27, 2011
8080250 Immunoconjugates with an intracellularly-cleavable linkage Dec. 20, 2011
8071093 Fully human anti-epidermal growth factor receptor antibodies Dec. 6, 2011
8071072 Cytotoxicity mediation of cells evidencing surface expression of CD44 Dec. 6, 2011

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