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Browse by Category: Main > Health & Medicine
Class Information
Number: 424/181.1
Name: Drug, bio-affecting and body treating compositions > Conjugate or complex of monoclonal or polyclonal antibody, immunoglobulin, or fragment thereof with nonimmunoglobulin material > Conjugated via claimed linking group, bond, chelating agent, or coupling agent (e.g., conjugated to proteinaceous toxin via claimed linking group, bond, coupling agent, etc.) > Conjugated to nonproteinaceous bioaffecting compound (e.g., conjugated to cancer-treating drug, etc.)
Description: Subject matter wherein the nonimmunoglobulin material is a nonproteinaceous bioaffecting compound, such as a nonproteinaceous drug (e.g., a cancer-treating drug).










Patents under this class:
1 2 3 4 5 6 7 8 9

Patent Number Title Of Patent Date Issued
8709432 Methods for increasing efficacy of FOLR1 cancer therapy Apr. 29, 2014
8703714 Monomethylvaline compounds capable of conjugation to ligands Apr. 22, 2014
8673303 Cripto blocking antibodies and uses thereof Mar. 18, 2014
8663642 Anti-CD70 antibody-drug conjugates and their use for the treatment and prevention of cancer and immune disorders Mar. 4, 2014
8663643 Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use Mar. 4, 2014
8652479 Antibody-drug conjugates and methods Feb. 18, 2014
8637012 Genetic products differentially expressed in tumors and the use thereof Jan. 28, 2014
RE44704 Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents Jan. 14, 2014
8624003 Methods for preparation of antibody-maytansinoid conjugates Jan. 7, 2014
8617559 Anti-FcRH5 antibodies and immunoconjugates and methods of use Dec. 31, 2013
8613929 Methods and compositions for targeting agents into and across the blood-brain barrier and other endothelial cell microvascular barriers Dec. 24, 2013
8613930 Cross-linkers and their uses Dec. 24, 2013
8614301 Methods of treating cancer using anti CD24 antibodies Dec. 24, 2013
8609096 Monoclonal antibodies against PCBP-1 antigens, and uses therefor Dec. 17, 2013
8603483 Anti-integrin immunoconjugates, methods and uses Dec. 10, 2013
8597654 Adjuvant therapy with an anti-ERBB2 antibody conjugated to a maytansiniod Dec. 3, 2013
8598322 Anti CEACAM1 antibodies and methods of using same Dec. 3, 2013
8591889 Human monoclonal antibodies specific for CD22 Nov. 26, 2013
8586714 Dual variable domain immunoglobulins and uses thereof Nov. 19, 2013
8568728 Beta-glucuronide-linker drug conjugates Oct. 29, 2013
8568729 Anthracycline-antibody conjugates for cancer therapy Oct. 29, 2013
8563700 Synergistic effects Oct. 22, 2013
8562989 Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer Oct. 22, 2013
8545850 Anti-CD79B antibodies and immunoconjugates and methods of use Oct. 1, 2013
8541178 Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry Sep. 24, 2013
8524238 Cancer targets and uses thereof Sep. 3, 2013
8524240 Diagnosis and therapy of hematological malignancies Sep. 3, 2013
8512707 Methods of treating drug-resistant cancers Aug. 20, 2013
8496938 Anti-CD100 neutralizing neutralizing antibodies and methods of using the same Jul. 30, 2013
8486402 Anti-CD98 antibody Jul. 16, 2013
8481041 Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy Jul. 9, 2013
8481042 Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents Jul. 9, 2013
8470329 Combination therapy with antibody-drug conjugates Jun. 25, 2013
8470330 PSMA antibodies and uses thereof Jun. 25, 2013
8460661 Methods of using antibodies that bind the glutamate ligand binding region of Notch1 Jun. 11, 2013
8455622 Variant target binding agents and uses thereof Jun. 4, 2013
8444990 Antibody-induced apoptosis May. 21, 2013
8431130 IL-18 binding proteins Apr. 30, 2013
8425912 Immunoconjugates with an intracellularly-cleavable linkage Apr. 23, 2013
8388973 Compositions and methods for the treatment of tumor of hematopoietic origin Mar. 5, 2013
8361464 Anthracycline-Antibody Conjugates for Cancer Therapy Jan. 29, 2013
8362215 Antibodies immunoreactive with heregulin-coupled HER3 Jan. 29, 2013
8343496 Anti-CD74 immunoconjugates and methods Jan. 1, 2013
RE43899 Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents Jan. 1, 2013
8313745 Compositions against cancer antigen LIV-1 and uses thereof Nov. 20, 2012
8293206 Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment Oct. 23, 2012
8277803 Cancerous disease modifying antibodies Oct. 2, 2012
8268317 Camptothecin-binding moiety conjugates Sep. 18, 2012
8268318 Polyalkylene oxides having hindered ester-based biodegradable linkers Sep. 18, 2012
8268319 Immunoconjugates with an intracellularly-cleavable linkage Sep. 18, 2012

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