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Class Information
Number: 424/179.1
Name: Drug, bio-affecting and body treating compositions > Conjugate or complex of monoclonal or polyclonal antibody, immunoglobulin, or fragment thereof with nonimmunoglobulin material > Conjugated via claimed linking group, bond, chelating agent, or coupling agent (e.g., conjugated to proteinaceous toxin via claimed linking group, bond, coupling agent, etc.)
Description: Subject matter wherein a monoclonal or polyclonal antibody or immunoglobulin or fragment thereof is conjugated to a nonimmunoglobulin material via a linking group, a bond, a chelating agent, or a coupling agent that is specifically identified in the claim(s) by chemical name or chemical structure.










Sub-classes under this class:

Class Number Class Name Patents
424/180.1 Conjugate includes potentiator or composition comprising conjugate includes potentiator 82
424/181.1 Conjugated to nonproteinaceous bioaffecting compound (e.g., conjugated to cancer-treating drug, etc.) 404


Patents under this class:
1 2 3 4 5 6 7 8

Patent Number Title Of Patent Date Issued
8663642 Anti-CD70 antibody-drug conjugates and their use for the treatment and prevention of cancer and immune disorders Mar. 4, 2014
8663643 Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use Mar. 4, 2014
8637642 Antibody drug conjugates (ADC) that bind to 191P4D12 proteins Jan. 28, 2014
RE44704 Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents Jan. 14, 2014
8628749 Radioimmunoconjugates and uses thereof Jan. 14, 2014
8623373 Compositions and methods for treatment of angiogenesis in pathological lesions Jan. 7, 2014
8624003 Methods for preparation of antibody-maytansinoid conjugates Jan. 7, 2014
8613907 Compositions that inhibit proliferation of cancer cells Dec. 24, 2013
8614185 Fusion proteins of alpha-MSH derivatives and Fc Dec. 24, 2013
8609105 Auristatin drug linker conjugates Dec. 17, 2013
8604127 Conjugate of catechol-modified polyethylene glycol with protein or peptide and preparation method thereof Dec. 10, 2013
8586049 Antibody-drug conjugates Nov. 19, 2013
8568728 Beta-glucuronide-linker drug conjugates Oct. 29, 2013
8551495 Anti-FMD vaccine composition and preparation and use thereof Oct. 8, 2013
8545850 Anti-CD79B antibodies and immunoconjugates and methods of use Oct. 1, 2013
8524240 Diagnosis and therapy of hematological malignancies Sep. 3, 2013
8518403 Expression-enhanced polypeptides Aug. 27, 2013
8491908 Composite particle, contrast agent for photoacoustic imaging, and method for producing the composite particle Jul. 23, 2013
8481334 Method of attaching a ligand to a solid support Jul. 9, 2013
8481041 Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy Jul. 9, 2013
8481040 Carrier for targeting nerve cells Jul. 9, 2013
8481003 Anti-CD74 immunoconjugates and methods Jul. 9, 2013
8470329 Combination therapy with antibody-drug conjugates Jun. 25, 2013
8455622 Variant target binding agents and uses thereof Jun. 4, 2013
8449888 Vaccines based on targeting antigen to DCIR expressed on antigen-presenting cells May. 28, 2013
8425912 Immunoconjugates with an intracellularly-cleavable linkage Apr. 23, 2013
8409568 Mutant antibody Fc domains and fusion proteins thereof Apr. 2, 2013
8367065 Targeted polymeric prodrugs containing multifunctional linkers Feb. 5, 2013
8361461 Anti-IGF-IR antibodies and uses thereof Jan. 29, 2013
8349328 Rodent control agents comprising antibodies that binds to rodent specific peptide epitopes Jan. 8, 2013
8309094 Antibody-drug conjugates Nov. 13, 2012
8282934 Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology Oct. 9, 2012
8268317 Camptothecin-binding moiety conjugates Sep. 18, 2012
8268319 Immunoconjugates with an intracellularly-cleavable linkage Sep. 18, 2012
8252902 Antibody targeting compounds Aug. 28, 2012
8226945 Antibodies and immunoconjugates and uses therefor Jul. 24, 2012
8197847 Process for making polymers and supports comprising pendant sugar side groups Jun. 12, 2012
8192743 Releasable polymeric conjugates based on aliphatic biodegradable linkers Jun. 5, 2012
8153114 Hyperglycosylated mammalian IL-7 IgG conjugate composition Apr. 10, 2012
8142781 Fusion proteins for blood-brain barrier delivery Mar. 27, 2012
8124073 Targeting of glycoprotein therapeutics Feb. 28, 2012
8124094 Immunoglobulin Fc fragment modified by non-peptide polymer and pharmaceutical composition comprising the same Feb. 28, 2012
8119101 Anti-CD74 immunoconjugates and methods of use Feb. 21, 2012
8088387 Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates Jan. 3, 2012
8088884 Multi-armed forms of activated polyoxazoline and methods of synthesis thereof Jan. 3, 2012
8067006 Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites Nov. 29, 2011
8067005 Divalent antibody fragments Nov. 29, 2011
8057798 Vaccines based on targeting antigen to DCIR expressed on antigen-presenting cells Nov. 15, 2011
8034352 Tetrameric cytokines with improved biological activity Oct. 11, 2011
8034959 Methods of treating cancer with an antibody-drug conjugate Oct. 11, 2011

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