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Class Information
Number: 424/178.1
Name: Drug, bio-affecting and body treating compositions > Conjugate or complex of monoclonal or polyclonal antibody, immunoglobulin, or fragment thereof with nonimmunoglobulin material
Description: Subject matter involving a monoclonal or polyclonal antibody, immunoglobulin, or fragment thereof that is coupled to a nonimmunoglobulin material via a single covalent bond or via a linking chemical group, or which is coupled to a nonimmunoglobulin material via noncovalent means (e.g., via chelation or adsorption).

Sub-classes under this class:

Class Number Class Name Patents
424/182.1 Conjugate includes potentiator; or composition comprising conjugate includes potentiator 117
424/183.1 Conjugated to proteinaceous toxin or fragment thereof (e.g., conjugated to diphtheria toxin, pseudomonas exotoxin, ricin, gelonin, abrin, etc.) 447
424/179.1 Conjugated via claimed linking group, bond, chelating agent, or coupling agent (e.g., conjugated to proteinaceous toxin via claimed linking group, bond, coupling agent, etc.) 360

Patents under this class:

Patent Number Title Of Patent Date Issued
8709431 Enediyne compounds, conjugates thereof, and uses and methods therefor Apr. 29, 2014
8709430 Cancer treatment kits comprising therapeutic antibody conjugates that bind to aminophospholipids Apr. 29, 2014
8703918 Isolated monoclonal antibody or fragment thereof binding prostate specific membrane antigen, conjugates and uses thereof Apr. 22, 2014
8703427 Biological materials and uses thereof Apr. 22, 2014
8703143 Antibodies of the ED-B domain of fibronectin, their construction and uses Apr. 22, 2014
8685920 Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates and methods of making said conjugates Apr. 1, 2014
8680247 Monoclonal antibodies against glypican-3 Mar. 25, 2014
8679785 Knobs and holes heteromeric polypeptides Mar. 25, 2014
8679492 Humanized antibodies that bind to CD19 and their uses Mar. 25, 2014
8679488 Targeting of bone marrow neovasculature Mar. 25, 2014
8679484 Method for removal of toxins from mucosal membranes Mar. 25, 2014
8673309 Methods for measuring high molecular weight complexes of fibrinogen with fibronectin and fibulin-1 Mar. 18, 2014
8673305 Methods of treatment with antibodies against the extracellular loops of C5aR Mar. 18, 2014
8668910 Antibodies that specifically bind to the EphA2 receptor Mar. 11, 2014
8663643 Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use Mar. 4, 2014
8663642 Anti-CD70 antibody-drug conjugates and their use for the treatment and prevention of cancer and immune disorders Mar. 4, 2014
8658433 Dye compounds as photoactive agents Feb. 25, 2014
8652546 Morinda citrifolia based formulations for regulating T cell immunomodulation in neonatal stock animals Feb. 18, 2014
8652479 Antibody-drug conjugates and methods Feb. 18, 2014
8647636 Low antigen-dose immunization utilizing overlapping peptides for maximizing T-helper cell 1 (Th1) immunity against a pathogen Feb. 11, 2014
8642357 Semaphorin 7A plays a critical role in TGF-.beta..sub.1-induced pulmonary fibrosis and alveolar destruction Feb. 4, 2014
8637642 Antibody drug conjugates (ADC) that bind to 191P4D12 proteins Jan. 28, 2014
8637028 Adjuvant incorporation in immunonanotherapeutics Jan. 28, 2014
8637027 Anti c-Met antibodies Jan. 28, 2014
8637012 Genetic products differentially expressed in tumors and the use thereof Jan. 28, 2014
RE44704 Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents Jan. 14, 2014
8628776 Human binding molecules against enterococci and Staphylococcus Jan. 14, 2014
8628771 CA IX-specific inhibitors Jan. 14, 2014
8623373 Compositions and methods for treatment of angiogenesis in pathological lesions Jan. 7, 2014
8623349 Systems, methods and microrganisms for antibody production with type III secretion system Jan. 7, 2014
8617558 Camptothecin-binding moiety conjugates Dec. 31, 2013
8617557 Antibody fusion with IL-12 proteins with disrupted heparin-binding activity Dec. 31, 2013
8617556 Gram-positive bacteria specific binding compounds Dec. 31, 2013
8617514 Tumor-targeted nanodelivery systems to improve early MRI detection of cancer Dec. 31, 2013
8614185 Fusion proteins of alpha-MSH derivatives and Fc Dec. 24, 2013
8613929 Methods and compositions for targeting agents into and across the blood-brain barrier and other endothelial cell microvascular barriers Dec. 24, 2013
8613928 Immunizing composition and method for inducing an immune response against the .beta.-secretase cleavage site of amyloid precursor protein Dec. 24, 2013
8613907 Compositions that inhibit proliferation of cancer cells Dec. 24, 2013
8609111 Antibodies against clostridium difficile toxins and uses thereof Dec. 17, 2013
8609104 Treatment of B-cell cancers with anti-CD70 antibody-drug conjugates Dec. 17, 2013
8609103 Megalin-based delivery of therapeutic compounds to the brain and other tissues Dec. 17, 2013
8609092 Antibody drug conjugates (ADC) that bind to 161P2F10B proteins Dec. 17, 2013
8604171 High affinity, anti-human IgE antibodies Dec. 10, 2013
8604169 Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer Dec. 10, 2013
8603477 Use of anti-CS1 antibodies for treatment of rare lymphomas Dec. 10, 2013
8603466 Agonist antibodies against TSHR Dec. 10, 2013
8598322 Anti CEACAM1 antibodies and methods of using same Dec. 3, 2013
8597654 Adjuvant therapy with an anti-ERBB2 antibody conjugated to a maytansiniod Dec. 3, 2013
8597653 Asymmetrically branched polymer conjugates and microarray assays Dec. 3, 2013
8591904 Asymmetrically branched polymer conjugates and microarray assays Nov. 26, 2013

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