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Class Information
Number: 424/177.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Reduced antigenicity, reduced ability to bind complement, or reduced numbers of activated complement components (e.g., free from aggregated, denatured, fragmented, or polymerized immunoglobulins; free from proteolytic enzymes, etc.)
Description: Subject matter involving an immunoglobulin preparation from which aggregated, denatured, fragmented, or polymerized immunoglobulins have been removed or prevented from forming; or from which plasma proteins, such as proteolytic enzymes, that contaminate an immunoglobulin preparation have been removed; or that has been treated to reduce the number of activated complement components.










Patents under this class:
1 2 3

Patent Number Title Of Patent Date Issued
8652474 Composition comprising antibody that binds to domain II of HER2 and acidic variants thereof Feb. 18, 2014
8609090 Specific binding agents to hepatocyte growth factor Dec. 17, 2013
8512706 Compositions of F(ab').sub.2 antibody fragments Aug. 20, 2013
8470328 Purification method which prevents denaturation of an antibody Jun. 25, 2013
8435527 Purification method which prevents denaturation of an antibody May. 7, 2013
8404236 Method of identifying membrane Ig specific antibodies and use thereof for targeting immunoglobulin-producing precursor cells Mar. 26, 2013
8362217 Purification of proteins Jan. 29, 2013
8350013 Arginine wash in protein purification using affinity chromatography Jan. 8, 2013
8323654 Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules Dec. 4, 2012
8293242 Ultra-high yield of alpha-1-anti-trypsin Oct. 23, 2012
8231876 Purified antibody composition Jul. 31, 2012
8188242 Chromatography purification of antibodies May. 29, 2012
8163886 Purification of proteins Apr. 24, 2012
8124743 Purification of a bivalently active antibody using a non-chromatographic method Feb. 28, 2012
8093360 Antibodies that bind B. anthracis exotoxin, formulations thereof, and methods of use Jan. 10, 2012
8093364 Enhanced purification of antibodies and antibody fragments by apatite chromatography Jan. 10, 2012
8084032 Purification method which prevents denaturation of an antibody Dec. 27, 2011
8075893 Pharmaceutical composition of F(ab').sub.2 antibody fragments and a process for the preparation thereof Dec. 13, 2011
8058407 Purification of acidic proteins using ceramic hydroxyapatite chromatography Nov. 15, 2011
8017115 Therapeutical use of anti-myelin associated glycoprotein (MAG) antibodies Sep. 13, 2011
8017740 Enhanced capacity and purification of antibodies by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers Sep. 13, 2011
7928205 Methods for refolding of recombinant antibodies Apr. 19, 2011
7879331 Ultra-high yield intravenous immune globulin preparation Feb. 1, 2011
7879332 Ultra-high yield intravenous immune globulin preparation Feb. 1, 2011
7863426 Antibody purification Jan. 4, 2011
7847071 Antibody purification by protein a and ion exchange chromatography Dec. 7, 2010
7834162 Methods and systems for isolating target molecules from complex solutions by column-chromatography using eluants containing organic solvents Nov. 16, 2010
7825223 Methods of purifying anti A .beta. antibodies Nov. 2, 2010
7820799 Methods of purifying Fc region containing proteins Oct. 26, 2010
7744890 Methods and compositions with reduced opalescence Jun. 29, 2010
7714111 Arginine derivative wash in protein purification using affinity chromatography May. 11, 2010
7691980 Enhanced capacity and purification of antibodies by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers Apr. 6, 2010
7666413 Method of reducing viscosity of high concentration protein formulations Feb. 23, 2010
7662930 Polishing steps used in multi-step protein purification processes Feb. 16, 2010
7662386 Compositions and methods for WT1 specific immunotherapy Feb. 16, 2010
7611709 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives Nov. 3, 2009
7553938 Method of providing a purified, virus safe antibody preparation Jun. 30, 2009
7485303 Pharmaceutical composition of F(ab')2 antibody fragments Feb. 3, 2009
7452539 Stabilizing polypeptides which have been exposed to urea Nov. 18, 2008
7413739 Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds Aug. 19, 2008
7368542 Method of altering the binding specificity of plasma proteins by oxidation-reduction reactions May. 6, 2008
7288254 Use of immunotoxins to induce immune tolerance to pancreatic islet transplantation Oct. 30, 2007
7241592 Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use Jul. 10, 2007
7186410 Method for preparing human immunoglobulin concentrates for therapeutic use Mar. 6, 2007
7138120 Process for producing immunoglobulins for intravenous administration and other immunoglobulin products Nov. 21, 2006
7125552 Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates Oct. 24, 2006
7041798 Method for the chromatographic fractionation of plasma or serum, preparations, so obtained, and their use May. 9, 2006
7014847 Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders Mar. 21, 2006
6893639 Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates May. 17, 2005
6875432 Reduced-viscosity concentrated protein formulations Apr. 5, 2005

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