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Class Information
Number: 424/143.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Monoclonal antibody or fragment thereof (i.e., produced by any cloning technology) > Binds receptor
Description: Subject matter involving a monoclonal antibody or antigen-binding fragment thereof whose antigen-binding site(s) will combine with a free or cell-associated receptor.

Sub-classes under this class:

Class Number Class Name Patents
424/144.1 Receptor integral to or derived from a lymphocytic or lymphocytic-like cell (e.g., nk cell, etc.) 615

Patents under this class:

Patent Number Title Of Patent Date Issued
8524236 Methods of antagonizing the binding of CD40 to CD40L with CD40L-specific monovalent polypeptides in autoimmune individuals Sep. 3, 2013
8518889 Method of treating cancer with antibodies against long-form leukotriene B4 receptor BLT2 Aug. 27, 2013
8518404 Activatable binding polypeptides and methods of identification and use thereof Aug. 27, 2013
8513199 Methods for treating conditions associated with c-fms Aug. 20, 2013
8512698 Compositions and methods for diagnosing and treating an inflammation Aug. 20, 2013
8506963 Anti-EFGRv3 monoclonal antibody Aug. 13, 2013
8506960 Antibody molecule for human GM-CSF receptor alpha Aug. 13, 2013
8496937 Preparation of isolated agonist anti-EDAR monoclonal antibodies Jul. 30, 2013
8496929 Inotropic effects of antibodies on cardiac contraction Jul. 30, 2013
RE44389 Methods of inhibiting the binding of P-selectin to PSGL-1 with anti-P-selectin antibodies Jul. 23, 2013
8492119 Antibody to human IL-3 receptor alpha chain Jul. 23, 2013
8491914 Dock-and-lock (DNL) complexes for delivery of interference RNA Jul. 23, 2013
8491898 Monoclonal antibodies against CD30 lacking in fucosyl residues Jul. 23, 2013
8486409 Alpha-emitting constructs and uses thereof Jul. 16, 2013
8486396 Compositions and methods for diagnosing and treating an inflammation Jul. 16, 2013
8486395 Anti-CD19 antibodies Jul. 16, 2013
8486394 Generation and Profiling of fully human hucal gold-derived therapeutic antibodies specific for human CD38 Jul. 16, 2013
8481683 Human antibodies that bind CD22 and uses thereof Jul. 9, 2013
8481034 Anti-VEGFR-3 antibody compositions Jul. 9, 2013
8475794 Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases Jul. 2, 2013
8475793 Engineered anti-TSLPR antibodies Jul. 2, 2013
8470326 Monoclonal antibody therapy for pancreas cancer Jun. 25, 2013
8470324 Fusion polypeptides capable of activating receptors Jun. 25, 2013
8470322 Anti sulfatides and anti sufated proteoglycans antibodies and their use Jun. 25, 2013
8470316 Agents for suppressing damage to transplanted islets after islet transplantation Jun. 25, 2013
8465745 Chimeric antigens for eliciting an immune response Jun. 18, 2013
8465737 Three-dimensional structure of complement receptor type 2 and uses thereof Jun. 18, 2013
8461304 Antibodies Jun. 11, 2013
8460669 Compositions and methods for identifying response targets and treating flavivirus infection responses Jun. 11, 2013
8460668 Interferon alpha receptor I antibodies and their use Jun. 11, 2013
8460667 EPHA2 receptor antagonist antibodies Jun. 11, 2013
8460662 Compositions and methods relating to anti-IGF-1 receptor antibodies Jun. 11, 2013
8460661 Methods of using antibodies that bind the glutamate ligand binding region of Notch1 Jun. 11, 2013
8460659 Toll-like receptor 3 antagonists for the treatment of metabolic and cardiovascular diseases Jun. 11, 2013
8460657 Modulation of the TrpV: Vps10p receptor system for the treatment of pain Jun. 11, 2013
8455622 Variant target binding agents and uses thereof Jun. 4, 2013
8454965 Method for the treatment of multiple sclerosis Jun. 4, 2013
8454962 Alpha-4-beta-7 heterodimer specific antagonist antibody Jun. 4, 2013
8454961 Alpha-4-beta-7 heterodimer specific antagonist antibody Jun. 4, 2013
8454960 Multispecific antibody targeting and multivalency through modular recognition domains Jun. 4, 2013
8454958 Methods for detecting and inhibiting angiogenesis Jun. 4, 2013
8450464 Human monoclonal antibodies that bind CXCR4 May. 28, 2013
8444983 Composition of anti-ENDO180 antibodies and methods of use for the treatment of cancer and fibrotic diseases May. 21, 2013
8444982 Anti-IGF-IR antibodies and uses thereof May. 21, 2013
8444981 Alpha-4 beta-7 heterodimer specific antagonist antibody May. 21, 2013
8440187 Use application of sugar chain-recognizing receptor May. 14, 2013
8440186 P2X7 epitopes May. 14, 2013
8440167 Multimodal imaging of atherosclerotic plaque targeted to LOX-1 May. 14, 2013
8435948 Methods for inhibiting osteoclastic bone resorption and bone loss comprising administration of an anti-FSH or anti-FSHR antibody May. 7, 2013
8435749 Anti-CDH3 antibodies labeled with radioisotope label and uses thereof May. 7, 2013

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