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Class Information
Number: 424/141.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Monoclonal antibody or fragment thereof (i.e., produced by any cloning technology)
Description: Subject matter involving an antibody or fragment thereof produced by a clone of cells or cell line, which clone of cells or cell line is derived from a single antibody-producing cell or antibody-fragment-producing cell, wherein said antibody or fragment thereof is identical to all other antibodies or fragments thereof produced by that clone of cells or cell line.

Sub-classes under this class:

Class Number Class Name Patents
424/150.1 Binds bacterium or component thereof or substance produced by said bacterium 297
424/146.1 Binds enzyme 180
424/152.1 Binds eukaryotic cell or component thereof or substance produced by said eukaryotic cell 519
424/145.1 Binds hormone or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., cytokine, etc.); or binds serum protein, plasma protein (e.g., tpa, etc.), or fibrin 1,057
424/151.1 Binds parasitic organism (i.e., parasitic protozoan, multicellular ectoparasite (e.g., flea, tick, mite, etc.), or multicellular endoparasite (e.g., parasitic worm, etc.)) or component thereof or substance produced by said parasitic organism 79
424/143.1 Binds receptor 1,295
424/147.1 Binds virus or component thereof 212
424/142.1 Human 676

Patents under this class:

Patent Number Title Of Patent Date Issued
8710192 PCSK9 antagonists Apr. 29, 2014
8709425 Antibodies to non-functional P2X.sub.7 receptor Apr. 29, 2014
8709422 Methods and compositions to treat and detect misfolded-SOD1 mediated diseases Apr. 29, 2014
8709413 Treatment of celiac disease with IgA Apr. 29, 2014
8709409 Method for treating rheumatoid arthritis by administering an anti-IL-6 antibody and methotrexate Apr. 29, 2014
8703143 Antibodies of the ED-B domain of fibronectin, their construction and uses Apr. 22, 2014
8703141 Method for treating Crohn's disease by administering an anti-IL-12 antibody Apr. 22, 2014
8703140 Inhibition of factor B, the alternative complement pathway and methods related thereto Apr. 22, 2014
8703139 Monoclonal antibodies and binding fragments thereof directed to the melanocortin-4 receptor and their use in the treatment of cachexia and related conditions and diseases Apr. 22, 2014
8703138 Treatment of inflammatory diseases by inhibiting cold-inducible RNA-binding protein (CIRP) Apr. 22, 2014
8703137 Treatment of tauopathies Apr. 22, 2014
8703134 Targeted cryptosporidium biocides Apr. 22, 2014
8691233 Antibody molecules having binding specificity for human IL-13 Apr. 8, 2014
8691231 Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibo Apr. 8, 2014
8691222 NLRR-1 antagonists and uses thereof Apr. 8, 2014
8686154 Compounds and compositions for delivering active agents Apr. 1, 2014
8686119 Variants of humanized immunomodulatory monoclonal antibodies Apr. 1, 2014
8685660 Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma Apr. 1, 2014
8685395 Methods of antagonizing signal transduction in dorsal root ganglion cells Apr. 1, 2014
8679503 Methods, compositions and kits relating to chitnases and chitnase-like molecules and inflammation disease Mar. 25, 2014
8679498 Anti-N3PGLU amyloid beta peptide antibodies and uses thereof Mar. 25, 2014
8679496 Anti-serum albumin single variable domains Mar. 25, 2014
8679485 Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis Mar. 25, 2014
8673306 Compositions and methods of use for antibodies of dickkopf-1 Mar. 18, 2014
8673305 Methods of treatment with antibodies against the extracellular loops of C5aR Mar. 18, 2014
8673300 Therapeutic compositions and methods for the prevention of autoimmune diseases Mar. 18, 2014
8673299 Anti-RANTES antibodies Mar. 18, 2014
8673298 Stabilized compositions of proteins having a free thiol moeity Mar. 18, 2014
8669047 Real-time detection of influenza virus Mar. 11, 2014
8668910 Antibodies that specifically bind to the EphA2 receptor Mar. 11, 2014
8668909 Anti MIF antibodies Mar. 11, 2014
8664368 Fully human monoclonal antibody to VEGF, preparation method and use thereof Mar. 4, 2014
8663641 Anti-PSGL-1 antibodies Mar. 4, 2014
8663639 Formulations for treating ocular diseases and conditions Mar. 4, 2014
8663636 Method of treating a malignant tumor by administering antibodies directed to DLL4 Mar. 4, 2014
8663634 Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity Mar. 4, 2014
8658169 Antibodies against IL-25 Feb. 25, 2014
8658168 Compositions and methods for homoconjugates of antibodies which induce growth arrest of apoptosis of tumor cells Feb. 25, 2014
8658167 Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis Feb. 25, 2014
8652475 Inhibition of factor B, the alternative complement pathway and methods related thereto Feb. 18, 2014
8652474 Composition comprising antibody that binds to domain II of HER2 and acidic variants thereof Feb. 18, 2014
8652473 Antibodies to EGF receptor epitope peptides and uses thereof Feb. 18, 2014
8652471 Methods of treating coagulopathies using antibodies against tissue factor pathway inhibitor Feb. 18, 2014
8652467 Dek protein compositions and methods of using the same Feb. 18, 2014
8652466 Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for Fc.gamma.R.sub.activating and Fc.gamma.R.sub.inhibiting Feb. 18, 2014
8647625 Anti-CD154 antibodies Feb. 11, 2014
8647624 Treatment of immune disorders with anti-CD70 antibody Feb. 11, 2014
8647617 Methods for modulating inflammatory and/or immune responses Feb. 11, 2014
8642357 Semaphorin 7A plays a critical role in TGF-.beta..sub.1-induced pulmonary fibrosis and alveolar destruction Feb. 4, 2014
8642037 Antibodies to insulin-like growth factor I receptor Feb. 4, 2014

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