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Class Information
Number: 424/136.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, cdr-grafted, mutated, etc.) > Bispecific or bifunctional, or multispecific or multifunctional, antibody or fragment thereof
Description: Subject matter involving an antibody or fragment thereof that is bispecific or bifunctional or multispecific or multifunctional.










Patents under this class:
1 2 3 4 5 6 7

Patent Number Title Of Patent Date Issued
6036955 Kits and methods for the specific coagulation of vasculature Mar. 14, 2000
6027725 Multivalent antigen-binding proteins Feb. 22, 2000
6025165 Methods for producing multivalent antigen-binding proteins Feb. 15, 2000
6024955 Peptides and monoclonal antibodies Feb. 15, 2000
6015560 Antibody recognizing endothelial cell ligand for leukocyte CR3 Jan. 18, 2000
6004554 Methods for targeting the vasculature of solid tumors Dec. 21, 1999
5993818 Use of autoantibodies for tumor therapy and prophylaxis Nov. 30, 1999
5985276 Destruction of contaminating tumor cells in stem cell transplants using bispecific antibodies Nov. 16, 1999
5980896 Antibodies reactive with human carcinomas Nov. 9, 1999
5968512 Antibody recognizing endothelial cell ligand for leukocyte CR3 Oct. 19, 1999
5959084 Bispecific antibodies, methods of production and uses thereof Sep. 28, 1999
5951982 Methods to suppress an immune response with variant CD44-specific antibodies Sep. 14, 1999
5932214 Treatment for inflammatory bowel disease with VLA-4 blockers Aug. 3, 1999
5922845 Therapeutic multispecific compounds comprised of anti-Fc.alpha. receptor antibodies Jul. 13, 1999
5911987 Cell surface protein and effector cell bonding reagent Jun. 15, 1999
5897861 Bispecific reagents for AIDS therapy Apr. 27, 1999
5895811 Artificial positive controls derived from bifunctional conjugates Apr. 20, 1999
5869620 Multivalent antigen-binding proteins Feb. 9, 1999
5869274 Immuno-histochemical method that reduces background staining Feb. 9, 1999
5863538 Compositions for targeting the vasculature of solid tumors Jan. 26, 1999
5864019 Multivalent antigen-binding proteins Jan. 26, 1999
5861151 Soluble fusion molecules with binding specificity for cell adhesion molecules Jan. 19, 1999
5861156 Methods of delivering agents to target cells Jan. 19, 1999
5855886 Antibodies, and methods for their use Jan. 5, 1999
5854069 GD2 anti-idiotypic antibodies and uses thereof Dec. 29, 1998
5843440 Cellular and serum protein anchors for modulating pharmacokinetics Dec. 1, 1998
5840302 Treatment of bacterially-induced inflammatory diseases Nov. 24, 1998
5837243 Therapeutic compounds comprised of anti-Fc receptor antibodies Nov. 17, 1998
5837242 Multivalent and multispecific binding proteins, their manufacture and use Nov. 17, 1998
5830478 Method for delivering functional domains of diphtheria toxin to a cellular target Nov. 3, 1998
5798100 Multi-stage cascade boosting vaccine Aug. 25, 1998
5798448 AL-1 neurotrophic factor antibodies Aug. 25, 1998
5762930 Bispecific reagents for redirected targeting of human lipoproteins Jun. 9, 1998
5709859 Mixed specificity fusion proteins Jan. 20, 1998
5681566 Antibody conjugates with two or more covalently linked FC regions Oct. 28, 1997
5658568 Cytotoxic drug therapy Aug. 19, 1997
5654404 Protection against liver damage by HGF Aug. 5, 1997
5609869 Hybrid immunoglobulin-thrombolytic enzyme molecules which specifically bind a thrombus, and methods of their production and use Mar. 11, 1997
5603931 Method for delivering a bioactive molecule to a cellular target Feb. 18, 1997
5601819 Bispecific antibodies for selective immune regulation and for selective immune cell binding Feb. 11, 1997
5545403 Method for treating a mammal by administering a CHO-glycosylated antibody Aug. 13, 1996
5501854 Hybrid reagents capable of selectively releasing molecules into cells Mar. 26, 1996
5496549 Bispecific monoclonal antibodies, thrombolytic agent and method of cell lysis Mar. 5, 1996
5487890 Mammalian primate erythrocyte bound heteropolymerized monoclonal antibodies and methods of use thereof Jan. 30, 1996
5470570 Mammalian primate erythrocyte bound heteropolymerized monoclonal antibodies and methods of use thereof Nov. 28, 1995
5453269 Heterobifunctional antibodies having dual specificity for fibrin and thrombolylic agents and methods of use Sep. 26, 1995
5364612 Detection of cardiovascular lesions Nov. 15, 1994
5332567 Detection and treatment of infections with immunoconjugates Jul. 26, 1994
5273743 Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent Dec. 28, 1993
5262524 Method for the synthesis of trifunctional maleimide-antibody complex Nov. 16, 1993

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