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Class Information
Number: 424/136.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, cdr-grafted, mutated, etc.) > Bispecific or bifunctional, or multispecific or multifunctional, antibody or fragment thereof
Description: Subject matter involving an antibody or fragment thereof that is bispecific or bifunctional or multispecific or multifunctional.










Patents under this class:
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Patent Number Title Of Patent Date Issued
8372399 Bispecific antibodies and agents to enhance stem cell homing Feb. 12, 2013
8337845 A-beta binding polypeptides Dec. 25, 2012
8333969 Use of immunesuppressant receptor Dec. 18, 2012
8333968 Methods of inhibiting inflammation with antagonists to IL-17A, IL-17F, and IL-23P19 Dec. 18, 2012
8329169 Methods and compositions for the prevention and treatment of sepsis Dec. 11, 2012
8329873 Bispecific single chain Fv antibody molecules and methods of use thereof Dec. 11, 2012
8309087 Treatment with anti-ErbB2 antibodies Nov. 13, 2012
8298532 Fusion polypeptides capable of activating receptors Oct. 30, 2012
8287865 Class I anti-CEA antibodies and uses thereof Oct. 16, 2012
8277806 Use of trifunctional bispecific and trispecific antibodies for the treatment of malignant ascites Oct. 2, 2012
8273352 Humanized anti-factor D antibodies and uses thereof Sep. 25, 2012
8268310 Prevention and treatment of complement-associated eye conditions Sep. 18, 2012
8268314 Bispecific anti-VEGF/anti-ANG-2 antibodies Sep. 18, 2012
8263747 Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins Sep. 11, 2012
8258266 IP-10 antibodies and their uses Sep. 4, 2012
8246955 Substance specific to human PD-1 Aug. 21, 2012
8242247 Bivalent, bispecific antibodies Aug. 14, 2012
8236308 Composition comprising cross-species-specific antibodies and uses thereof Aug. 7, 2012
8236309 Use of bispecific antibodies to regulate immune responses Aug. 7, 2012
8226950 Recombinant anti-VLA4 antibody molecules Jul. 24, 2012
8227577 Bivalent, bispecific antibodies Jul. 24, 2012
8216805 Knobs and holes heteromeric polypeptides Jul. 10, 2012
8211440 Multivalent immunoglobulin-based bioactive assemblies Jul. 3, 2012
8211434 KLK-13 antibody inhibitor for treating dry eye Jul. 3, 2012
8211429 Neuropilin antagonists Jul. 3, 2012
8188231 Optimized FC variants May. 29, 2012
8178094 Methods for inhibiting tumor growth or reducing metastatic burden in a subject by administering FDF03 antibodies May. 15, 2012
8178095 Method of treating skin inflammation May. 15, 2012
8173130 Antibodies against flagellin and uses thereof May. 8, 2012
8168186 Therapeutic using a bispecific antibody May. 1, 2012
8168184 Bi-specific monoclonal antibody (specific for both CD3 and CD11B) therapeutic drug May. 1, 2012
8163287 Combination therapy of her expressing tumors Apr. 24, 2012
8147831 Anti-CD19 antibodies Apr. 3, 2012
8143387 Engineered antibody-stress protein fusions Mar. 27, 2012
8142791 Multi-modal cancer therapy using viral hitch-hiking Mar. 27, 2012
8137670 Method of identifying membrane IgE specific antibodies and use thereof for targeting IgE producing precursor cells Mar. 20, 2012
8133485 Bi-specific complexes for targeting cells involved in allergic-type reactions, compositions and uses thereof Mar. 13, 2012
8124085 Bispecific binding agents for modulating biological activity Feb. 28, 2012
8105596 Immunotherapy of B-cell malignancies using anti-CD22 antibodies Jan. 31, 2012
8097252 Methods and compositions for administering therapeutic and diagnostic agents Jan. 17, 2012
8084026 Multispecific binding molecules comprising connecting peptides Dec. 27, 2011
8075892 Treatment with anti-ErbB2 antibodies Dec. 13, 2011
8066989 Method of treating tumor growth and metastasis by using trifunctional antibodies to reduce the risk for GvHD in allogeneic antitumor cell therapy Nov. 29, 2011
8067005 Divalent antibody fragments Nov. 29, 2011
8062635 Bispecific antibody substituting for functional proteins Nov. 22, 2011
8034339 Prevention and treatment of amyloidogenic disease Oct. 11, 2011
8012470 Method for ex vivo immunization using heterologous intact bispecific and/or trispecific antibodies Sep. 6, 2011
8007791 Prevention and treatment of complement-associated eye conditions Aug. 30, 2011
8007796 Means and methods for the treatment of tumorous diseases Aug. 30, 2011
7951917 Method for making multispecific antibodies having heteromultimeric and common components May. 31, 2011

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