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Class Information
Number: 424/136.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, cdr-grafted, mutated, etc.) > Bispecific or bifunctional, or multispecific or multifunctional, antibody or fragment thereof
Description: Subject matter involving an antibody or fragment thereof that is bispecific or bifunctional or multispecific or multifunctional.










Patents under this class:
1 2 3 4 5 6 7

Patent Number Title Of Patent Date Issued
8709418 Pharmaceutical composition for treating CAPRIN-1 expressing cancer Apr. 29, 2014
8709421 Combination of the application of antibodies for immunostimulation together with glucocorticoids Apr. 29, 2014
8703135 Biological materials related to c-Met Apr. 22, 2014
8703143 Antibodies of the ED-B domain of fibronectin, their construction and uses Apr. 22, 2014
8679498 Anti-N3PGLU amyloid beta peptide antibodies and uses thereof Mar. 25, 2014
8679785 Knobs and holes heteromeric polypeptides Mar. 25, 2014
8663640 Methods using recombinant anti-epidermal growth factor receptor antibody compositions Mar. 4, 2014
8663638 Intraoperative trifunctional antibody application for prophylaxis of intraperitoneal tumor cell dissemination Mar. 4, 2014
8658168 Compositions and methods for homoconjugates of antibodies which induce growth arrest of apoptosis of tumor cells Feb. 25, 2014
8658175 Anti-EGFR antibodies and their uses Feb. 25, 2014
8642036 Treatment with anti-ErbB2 antibodies Feb. 4, 2014
8637024 Fusion antibodies for HIV therapy Jan. 28, 2014
8632777 Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen as diagnostic and therapeutic tools for prostate cancer Jan. 21, 2014
8628778 Humanized monoclonal antibodies to hepatocyte growth factor Jan. 14, 2014
8623361 Amino acid sequences directed against RANK-L and polypeptides comprising the same for the treatment of bone diseases and disorders Jan. 7, 2014
8623353 TLR2 antagonistic antibody and use thereof Jan. 7, 2014
8617549 Bispecific nanobodies as a therapeutic for alzheimer's disease Dec. 31, 2013
8613921 Antibodies that bind TGF-alpha and epiregulin Dec. 24, 2013
8614285 Photosensitizer based on polymer derivatives-photosensitizer conjugates for photodynamic therapy Dec. 24, 2013
8603473 Modified binding molecules comprising connecting peptides Dec. 10, 2013
8603479 Class I anti-CEA antibodies and uses thereof Dec. 10, 2013
8598321 Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins Dec. 3, 2013
8597898 Fusion polypeptides capable of activating receptors Dec. 3, 2013
8591896 Chemokine receptor binding polypeptides Nov. 26, 2013
8591903 Inhibition of TACE or amphiregulin for the modulation of EGF receptor signal transactivation Nov. 26, 2013
8586039 Degraded TPO agonist antibody Nov. 19, 2013
8586041 Human monoclonal antibodies to epidermal growth factor receptor (EGFR) Nov. 19, 2013
8580263 Anti-EGFR family antibodies, bispecific anti-EGFR family antibodies and methods of use thereof Nov. 12, 2013
8574577 VEGF antibodies comprising modular recognition domains Nov. 5, 2013
8574580 Monoclonal antibodies that recognize neurospheres or neural progenitor cells Nov. 5, 2013
8530627 Fc.gamma.RIIB specific antibodies and methods of use thereof Sep. 10, 2013
8524236 Methods of antagonizing the binding of CD40 to CD40L with CD40L-specific monovalent polypeptides in autoimmune individuals Sep. 3, 2013
8518403 Expression-enhanced polypeptides Aug. 27, 2013
8496936 Antagonists of IL-17A, IL-17F, and IL-23P19 Jul. 30, 2013
8496938 Anti-CD100 neutralizing neutralizing antibodies and methods of using the same Jul. 30, 2013
8491905 KLK-13 antibody inhibitor for treating dry eye Jul. 23, 2013
8486401 Monoclonal antibodies binding to TrkA and acting as NGF-antagonist molecules and their use for treating pain induced by NGF Jul. 16, 2013
8475794 Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases Jul. 2, 2013
8476409 Bispecific anti-IGF-1R and anti-ErbB3 antibodies Jul. 2, 2013
8475766 Dual specificity antibodies and methods of making and using Jul. 2, 2013
8470324 Fusion polypeptides capable of activating receptors Jun. 25, 2013
8440192 Bispecific binding agents for modulating biological activity May. 14, 2013
8435494 Mesothelin antibody protein fusions and methods of use May. 7, 2013
8435513 NOTCH1 receptor antibodies and methods of treatment May. 7, 2013
8425908 Treatment with anti-ErbB2 antibodies Apr. 23, 2013
8420092 Method of treating diabetes by administering an anti-NKp46 antibody Apr. 16, 2013
8414896 Recombinant anti-epidermal growth factor receptor antibody compositions Apr. 9, 2013
8404236 Method of identifying membrane Ig specific antibodies and use thereof for targeting immunoglobulin-producing precursor cells Mar. 26, 2013
8394375 Antibodies for amyloid specific peptides Mar. 12, 2013
8388965 Antibodies that bind IL-4 and/or IL-13 and their uses Mar. 5, 2013

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