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Class Information
Number: 424/135.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, cdr-grafted, mutated, etc.) > Single chain antibody
Description: Subject matter wherein the material is a single polypeptide chain that has antigen-binding capability.










Patents under this class:
1 2 3 4 5 6 7 8 9 10 11

Patent Number Title Of Patent Date Issued
8709418 Pharmaceutical composition for treating CAPRIN-1 expressing cancer Apr. 29, 2014
8710192 PCSK9 antagonists Apr. 29, 2014
8710194 Single-chain variable fragment (scFv) able to recognize and bind CD99 human protein Apr. 29, 2014
8703138 Treatment of inflammatory diseases by inhibiting cold-inducible RNA-binding protein (CIRP) Apr. 22, 2014
8703143 Antibodies of the ED-B domain of fibronectin, their construction and uses Apr. 22, 2014
8703920 Fully human antibodies against N-cadherin Apr. 22, 2014
8685395 Methods of antagonizing signal transduction in dorsal root ganglion cells Apr. 1, 2014
8685402 Neutralizing anti-influenza A virus antibodies and uses thereof Apr. 1, 2014
8679487 Anti-interleukin-4 receptor antibodies Mar. 25, 2014
8673298 Stabilized compositions of proteins having a free thiol moeity Mar. 18, 2014
8673300 Therapeutic compositions and methods for the prevention of autoimmune diseases Mar. 18, 2014
8658168 Compositions and methods for homoconjugates of antibodies which induce growth arrest of apoptosis of tumor cells Feb. 25, 2014
8658169 Antibodies against IL-25 Feb. 25, 2014
8652474 Composition comprising antibody that binds to domain II of HER2 and acidic variants thereof Feb. 18, 2014
8653243 Pertussis antibodies and uses thereof Feb. 18, 2014
8642357 Semaphorin 7A plays a critical role in TGF-.beta..sub.1-induced pulmonary fibrosis and alveolar destruction Feb. 4, 2014
8642036 Treatment with anti-ErbB2 antibodies Feb. 4, 2014
8642035 Anti-TrkB antibodies Feb. 4, 2014
8637015 Methods of antagonizing signal transduction in dorsal root ganglion cells Jan. 28, 2014
8637022 Functionalized polypeptides Jan. 28, 2014
8632777 Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen as diagnostic and therapeutic tools for prostate cancer Jan. 21, 2014
8629245 Immunoglobulin Fc libraries Jan. 14, 2014
8623356 Demibodies: dimerization-activated therapeutic agents Jan. 7, 2014
8614301 Methods of treating cancer using anti CD24 antibodies Dec. 24, 2013
8604171 High affinity, anti-human IgE antibodies Dec. 10, 2013
8603469 Methods of treating cancer with human monoclonal antibodies against interleukin 8 Dec. 10, 2013
8597646 Methods and compositons featuring TGF-beta antagonists for the treatment of marfan syndrome and associated disorders Dec. 3, 2013
8597659 Tetrameric cytokines with improved biological activity Dec. 3, 2013
8598321 Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins Dec. 3, 2013
8591893 Paratope and epitope of anti-mortalin antibody Nov. 26, 2013
8586037 Antibodies against IL-17BR Nov. 19, 2013
8586035 Use of IL-23 antagonists for treatment of infection Nov. 19, 2013
8586041 Human monoclonal antibodies to epidermal growth factor receptor (EGFR) Nov. 19, 2013
8580247 PS-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof Nov. 12, 2013
8574580 Monoclonal antibodies that recognize neurospheres or neural progenitor cells Nov. 5, 2013
8562984 Methods of treatment using anti-IL-20 antibodies Oct. 22, 2013
8551476 SP35 antibodies and uses thereof Oct. 8, 2013
8540988 Antibodies that bind polypeptides involved in the process of bone remodeling Sep. 24, 2013
8535671 Methods of reducing CRP and/or increasing serum albumin in patients in need using IL-6 antibodies of defined epitopic specificity Sep. 17, 2013
8535725 Porous-wall hollow glass microspheres as carriers for biomolecules Sep. 17, 2013
8524236 Methods of antagonizing the binding of CD40 to CD40L with CD40L-specific monovalent polypeptides in autoimmune individuals Sep. 3, 2013
8524672 Method for inhibiting BAFF-R activity Sep. 3, 2013
8518403 Expression-enhanced polypeptides Aug. 27, 2013
8501185 Dimeric molecular complexes Aug. 6, 2013
8486893 Treatment of conditions involving demyelination Jul. 16, 2013
8486406 Monoclonal antibodies as a medicament for the therapeutic and/or prophylactic treatment of swine-origin influenza A (H1N1) virus (S-OIV) infections Jul. 16, 2013
8486401 Monoclonal antibodies binding to TrkA and acting as NGF-antagonist molecules and their use for treating pain induced by NGF Jul. 16, 2013
8486398 Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds Jul. 16, 2013
8475793 Engineered anti-TSLPR antibodies Jul. 2, 2013
8470979 Humanized antibody molecules specific for IL-31 Jun. 25, 2013

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