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Class Information
Number: 424/134.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, cdr-grafted, mutated, etc.) > Antibody, immunoglobulin, or fragment thereof fused via peptide linkage to nonimmunoglobulin protein, polypeptide, or fragment thereof (i.e., antibody or immunoglobulin fusion protein or polypeptide)
Description: Subject matter involving a fusion protein or fusion polypeptide that includes (a) an antibody, immunoglobulin, or fragment thereof fused directly via a peptide bond to a nonimmunoglobulin protein, polypeptide, or fragment thereof or (b) an antibody, immunoglobulin, or fragment thereof fused indirectly via a peptide linker to a nonimmunoglobulin protein, polypeptide, or fragment thereof, which fusion protein or polypeptide is the expression product of a gene fusion.










Patents under this class:
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Patent Number Title Of Patent Date Issued
8710016 ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy Apr. 29, 2014
8703134 Targeted cryptosporidium biocides Apr. 22, 2014
8703143 Antibodies of the ED-B domain of fibronectin, their construction and uses Apr. 22, 2014
8685398 Chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer Apr. 1, 2014
8679493 Immunoglobulin Fc polypeptides Mar. 25, 2014
8669350 TNF receptor Fc fusion proteins and in vivo methods of use Mar. 11, 2014
8664363 Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease Mar. 4, 2014
8658168 Compositions and methods for homoconjugates of antibodies which induce growth arrest of apoptosis of tumor cells Feb. 25, 2014
8658174 GLP/1/exendin 4 IgG Fc fusion constructs for treatment of diabetes Feb. 25, 2014
8652466 Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for Fc.gamma.R.sub.activating and Fc.gamma.R.sub.inhibiting Feb. 18, 2014
8652479 Antibody-drug conjugates and methods Feb. 18, 2014
8647625 Anti-CD154 antibodies Feb. 11, 2014
8637021 Formulations for TACI-immunoglobulin fusion proteins Jan. 28, 2014
8637022 Functionalized polypeptides Jan. 28, 2014
8637023 Hemojuvelin fusion proteins Jan. 28, 2014
8637028 Adjuvant incorporation in immunonanotherapeutics Jan. 28, 2014
8628775 Methods of reducing T cell-mediated immune responses with multimeric P-selectin and/or E-selectin compounds Jan. 14, 2014
8618252 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto Dec. 31, 2013
8613907 Compositions that inhibit proliferation of cancer cells Dec. 24, 2013
8603474 Membrane transporter NaPi2b (SCL34A1) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy Dec. 10, 2013
8603473 Modified binding molecules comprising connecting peptides Dec. 10, 2013
8603469 Methods of treating cancer with human monoclonal antibodies against interleukin 8 Dec. 10, 2013
8597659 Tetrameric cytokines with improved biological activity Dec. 3, 2013
8591897 Anti-ERBB2 antibody adjuvant therapy Nov. 26, 2013
8586038 Chimeric immunoglobulin fusion proteins Nov. 19, 2013
8586039 Degraded TPO agonist antibody Nov. 19, 2013
8586531 Erythropoietin immunoglobulin fusion proteins Nov. 19, 2013
8586714 Dual variable domain immunoglobulins and uses thereof Nov. 19, 2013
8580274 Drug transporter, and adjuvant and vaccine each utilizing same Nov. 12, 2013
8574577 VEGF antibodies comprising modular recognition domains Nov. 5, 2013
8562988 Strategies for improved cancer vaccines Oct. 22, 2013
8563269 Modified antibody compositions, methods of making and using thereof Oct. 22, 2013
8557232 Stabilization of Fc-interferon-beta fusion proteins Oct. 15, 2013
8557242 ERBB2 antibodies comprising modular recognition domains Oct. 15, 2013
8557243 EFGR antibodies comprising modular recognition domains Oct. 15, 2013
8551476 SP35 antibodies and uses thereof Oct. 8, 2013
8551480 Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity Oct. 8, 2013
8541203 Activatable binding polypeptides and methods of identification and use thereof Sep. 24, 2013
8540987 Composition for neutralizing botulinus toxin type-A, and human anti-botulinus toxin type-A antibody Sep. 24, 2013
8535681 Sustained drug delivery system Sep. 17, 2013
8530627 Fc.gamma.RIIB specific antibodies and methods of use thereof Sep. 10, 2013
8530421 Isolated polypeptides used for treatment of inflammatory diseases and inhibiting cancer metastasis Sep. 10, 2013
8530189 Sustained drug delivery system Sep. 10, 2013
8529899 Human growth hormone immunoglobulin fusion proteins Sep. 10, 2013
8529898 Activatable binding polypeptides and methods of identification and use thereof Sep. 10, 2013
8529897 Inflammation-regulating compositions and methods Sep. 10, 2013
8524867 Optimized antibodies that target CD19 Sep. 3, 2013
8524232 Methods of treatment using taci-immunoglobulin fusion proteins Sep. 3, 2013
8524227 Anti-IL-TIF antibodies Sep. 3, 2013
8524217 MCP1-Ig fusion variants Sep. 3, 2013

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