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Class Information
Number: 424/133.1
Name: Drug, bio-affecting and body treating compositions > Immunoglobulin, antiserum, antibody, or antibody fragment, except conjugate or complex of the same with nonimmunoglobulin material > Structurally-modified antibody, immunoglobulin, or fragment thereof (e.g., chimeric, humanized, cdr-grafted, mutated, etc.)
Description: Subject matter involving an antibody, immunoglobulin, or fragment thereof that is purposely altered with respect to its amino acid sequence or glycosylation, or with respect to its composition of heavy and light chains or immunoglobulin regions or domains, as compared with that found in nature; or wherein the antibody, immunoglobulin, or fragment thereof is part of a larger, synthetic protein.










Sub-classes under this class:

Class Number Class Name Patents
424/134.1 Antibody, immunoglobulin, or fragment thereof fused via peptide linkage to nonimmunoglobulin protein, polypeptide, or fragment thereof (i.e., antibody or immunoglobulin fusion protein or polypeptide) 787
424/136.1 Bispecific or bifunctional, or multispecific or multifunctional, antibody or fragment thereof 313
424/135.1 Single chain antibody 529


Patents under this class:

Patent Number Title Of Patent Date Issued
8710194 Single-chain variable fragment (scFv) able to recognize and bind CD99 human protein Apr. 29, 2014
8709420 Pharmaceutical combination of pazopanib and topotecan to treat neuroblastoma, osteosarcoma, and rhabdomyosarcoma in a human Apr. 29, 2014
8709418 Pharmaceutical composition for treating CAPRIN-1 expressing cancer Apr. 29, 2014
8703920 Fully human antibodies against N-cadherin Apr. 22, 2014
8703143 Antibodies of the ED-B domain of fibronectin, their construction and uses Apr. 22, 2014
8703138 Treatment of inflammatory diseases by inhibiting cold-inducible RNA-binding protein (CIRP) Apr. 22, 2014
8703137 Treatment of tauopathies Apr. 22, 2014
8703135 Biological materials related to c-Met Apr. 22, 2014
8703134 Targeted cryptosporidium biocides Apr. 22, 2014
8703133 Antibody variants Apr. 22, 2014
8703132 Bispecific, tetravalent antigen binding proteins Apr. 22, 2014
8703131 Nanobodies against tumor necrosis factor-alpha Apr. 22, 2014
8703126 Reduced-viscosity concentrated protein formulations Apr. 22, 2014
8691228 Stable and soluble antibodies inhibiting TNF.alpha. Apr. 8, 2014
8691227 Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-.alpha. Apr. 8, 2014
8691226 Humanized anti-human tumor necrosis factor alpha monoclonal antibody and sequence thereof Apr. 8, 2014
8691225 Antibodies against the ectodomain of ErbB3 and uses thereof Apr. 8, 2014
8691224 Anti-A.beta. globulomer 5F7 antibodies Apr. 8, 2014
8686119 Variants of humanized immunomodulatory monoclonal antibodies Apr. 1, 2014
8685402 Neutralizing anti-influenza A virus antibodies and uses thereof Apr. 1, 2014
8685398 Chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer Apr. 1, 2014
8685397 Combination therapy for the treatment of ocular neovascular disorders Apr. 1, 2014
8685396 Monoclonal antibodies that neutralize anthrax protective antigen (PA) toxin Apr. 1, 2014
8685395 Methods of antagonizing signal transduction in dorsal root ganglion cells Apr. 1, 2014
8685393 Methods and compositions for the treatment and diagnosis of systemic anthrax infection Apr. 1, 2014
8680247 Monoclonal antibodies against glypican-3 Mar. 25, 2014
8680241 Humanized antibodies specific for HSP65-derived peptide-6 methods and uses thereof Mar. 25, 2014
8679785 Knobs and holes heteromeric polypeptides Mar. 25, 2014
8679500 Compositions containing antibodies for treating CD5+ HLA-DR+ B or T cell related diseases Mar. 25, 2014
8679497 Anti-ferroportin 1 monoclonal antibodies and uses thereof Mar. 25, 2014
8679496 Anti-serum albumin single variable domains Mar. 25, 2014
8679495 Use of anti-90K monoclonal antibodies for the prevention and treatment of tumors and metastases thereof Mar. 25, 2014
8679494 Antibodies specific to IL-17A and IL-17F Mar. 25, 2014
8679493 Immunoglobulin Fc polypeptides Mar. 25, 2014
8679492 Humanized antibodies that bind to CD19 and their uses Mar. 25, 2014
8679491 Method of modulating the activity of functional immune molecules Mar. 25, 2014
8679490 Binding polypeptides with diversified and consensus VH/VL hypervariable sequences Mar. 25, 2014
8673314 Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof Mar. 18, 2014
8673305 Methods of treatment with antibodies against the extracellular loops of C5aR Mar. 18, 2014
8673302 Anti-cMet antibody and its use for the detection and the diagnosis of cancer Mar. 18, 2014
8673301 YKL-40 monoclonal antibody Mar. 18, 2014
8673298 Stabilized compositions of proteins having a free thiol moeity Mar. 18, 2014
8669349 BCR-complex-specific antibodies and methods of using same Mar. 11, 2014
8668910 Antibodies that specifically bind to the EphA2 receptor Mar. 11, 2014
8668909 Anti MIF antibodies Mar. 11, 2014
8664363 Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease Mar. 4, 2014
8664362 Humanized and chimeric anti-properdin antibodies Mar. 4, 2014
8663950 Production of a monoclonal antibody therapeutic against west nile virus in plants Mar. 4, 2014
8663641 Anti-PSGL-1 antibodies Mar. 4, 2014
8663640 Methods using recombinant anti-epidermal growth factor receptor antibody compositions Mar. 4, 2014











 
 
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