| Patent Number |
Title Of Patent |
Date Issued |
| RE39616 |
Aminoindan derivatives |
May 8, 2007 |
| This invention is directed to compounds of the following formula: ##STR00001## wherein when a is 0, b is 1 or 2; when a is 1, b is 1, m is from 0-3, X is O or S, Y is halogeno, R.sub.1 is hydrogen C.sub.1-4 alkyl, R.sub.2 is hydrogen, C.sub.1-4 alkyl, or optionally substituted propa |
| RE38761 |
Styryl compounds which inhibit EGF receptor protein tyrosine kinase |
July 19, 2005 |
| A method of inhibiting cell proliferation in a patient suffering from such disorder comprising administering to said patient an effective amount of a composition comprising, in admixture with a pharmaceutically acceptable carrier, a compound, or a pharmaceutically acceptable salt thereof |
| RE33107 |
Compositions containing 1.alpha.-hydroxycholecalciferol for topical treatment of skin disorders |
November 7, 1989 |
| Cosmetic and dermatological compositions containing 1.alpha.-hydroxycholeciferol and a suitable carrier useful in topical treatment of skin disorders and methods employing same are disclosed. Compositions containing 1.alpha.,25-dihydroxycholecalciferol and a suitable carrier and met |
| 7625946 |
Propargylated aminoindans, processes for preparation, and uses thereof |
December 1, 2009 |
| This invention provides compounds having the structure: ##STR00001## wherein R.sub.1 is methyl and R.sub.2 is H, or R.sub.1 is ethyl and R.sub.2 is hydroxymethyl; R.sub.3 is H or propargyl; and R.sub.4 is either H or t-butyloxycarbonyl; or an enantiomer or a pharmaceutically acceptab |
| 7622544 |
Process for preparation of biodegradable polymers and resins from proteins, and plastics obtaine |
November 24, 2009 |
| A method for preparing polyester/polyamide polymers, resins and plastics from proteins is disclosed. Using nitrous acid or nitrous oxide, a protein is converted to a hydroxyl carboxyl polyamide protomer. Protomers are condensed through hydroxyl and carboxyl groups to make inter-protomer |
| 7615209 |
Compositions of NDV and methods of use thereof for treatment of cancer |
November 10, 2009 |
| The present invention discloses methods for inducing regression of a tumor in a subject by administering a pharmaceutical composition comprising a lentogenic strain of Newcastle disease virus (NDV). A preferred viral strain of NDV for inducing regression of a tumor in a subject is a clon |
| 7608598 |
Use of lipid conjugates in the treatment of conjunctivitis |
October 27, 2009 |
| In one embodiment, the invention provides a method of suppressing, inhibiting, preventing, or treating conjunctivitis in a subject, comprising the step of administering an effective amount of a lipid or phospholipid moiety bound via an ester or amide bond to a physiologically accepta |
| 7605132 |
Protective factors against inflammation, burns and noxious stimuli |
October 20, 2009 |
| Peptide factors isolated from skin following exposure to chemical or thermal injury and treatment with iodine preparations are capable of reducing or ameliorating the extent of injury when administered to other animals. Specific peptides, including fragments of histone H2A and fibrin |
| 7534605 |
CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of |
May 19, 2009 |
| An isolated polypeptide is provided. The isolated polypeptide comprising an antigen recognition domain capable of specifically binding a CD44 polypeptide as set forth in SEQ ID NO: 2 and incapable of binding a CD44 polypeptide selected from the group consisting of: SEQ ID NO: 4 or 6. |
| 7528947 |
Nanoparticles functionalized probes and methods for preparing such probes |
May 5, 2009 |
| The present invention provides probes functionalized with nanoparticles, methods for binding nanoparticles to the probes and the use of such probes in nanometer scale imaging techniques. More specifically, the present invention provides a tip device having at least a portion thereof |
| 7528227 |
Histone H2A peptide derivatives and uses thereof |
May 5, 2009 |
| Peptides derived from a segment of human histone H2A, the segment corresponding to amino acid residues 36-44 of human histone H2A, are capable of reducing or ameliorating the extent of injury induced by noxious stimuli when administered to animals. Pharmaceutical compositions and met |
| 7504384 |
Use of lipid conjugates in the treatment of infection |
March 17, 2009 |
| This invention provides compounds and methods of use thereof in suppressing, inhibiting, preventing, or treating a pathogenic effect on a cell, including, inter alia, infection with intracellular pathogens. Also provided are compounds and methods of use thereof in suppressing, inhibi |
| 7504099 |
Methods of inducing or enhancing connective tissue repair |
March 17, 2009 |
| This invention provides method for repairing, regenerating, treating, or inducing the repair of an injury, a defect or a condition of a connective tissue of a subject. This invention provides a method of regenerating, enhancing, inducing repair and/or development of connective tissue as |
| 7494783 |
Method for assessing trait anxiety by determining cholinergic status |
February 24, 2009 |
| The invention provides methods/kits for assessing levels of trait or state anxiety in a subject by comparing genotypes and/or expression patterns at the ACHE, PON1 and/or BChE genes to the genotype and/or expression pattern of the genes in a reference population whose genotype and/or |
| 7485476 |
Terahertz radiating device based on semiconductor coupled quantum wells |
February 3, 2009 |
| A method is presented for fabricating a semiconductor device operable to generate a THz spectral range radiation in response to an external field. According to this method, a heterostructure is formed from selected layers. The layers include at least first and second semiconductor layers |
| 7479963 |
Method and system for performing computer graphic simulation of a fluid using target-driven cont |
January 20, 2009 |
| Method and system for efficiently controlling animated smoke which utilizes a sequence of target smoke states to generate a smoke simulation in which the smoke is driven towards each of these targets in turn, while exhibiting natural-looking interesting smoke-like behavior. This control |
| 7477284 |
System and method for capturing and viewing stereoscopic panoramic images |
January 13, 2009 |
| Method and apparatus for generating images of a scene from image data of the scene and displaying the images to provide a sense of depth. In some embodiments of the method and apparatus the generated images are mosaics. |
| 7456154 |
Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof |
November 25, 2008 |
| The invention relates to an antisense oligonucleotide targeted to the coding region of the human acetylcholinesterase (AChE), which selectively suppresses the AChE-R isoform of the enzyme. The antisense oligonucleotide is intended for use in the treatment and/or prevention of neuromu |
| 7425322 |
Responsive biomedical composites |
September 16, 2008 |
| A responsive polymeric system including a responsive polymeric component capable of undergoing a transition that results in a sharp increase in viscosity in response to a triggering effected at a predetermined body site. The system includes a solid non-ceramic reinforcing component which |
| 7407753 |
Methods, kits and pharmaceutical compositions for diagnosing, delaying onset of, preventing and/ |
August 5, 2008 |
| The present invention uncovers a highly significant association of SNPs in the CNR2 locus, encoding the cannabinoid receptor 2 protein, with osteoporosis. Methods and kits for determining predisposition to osteoporosis, improving diagnosis in individuals suspected of having osteoporo |
| 7393938 |
Use of lipid conjugates in the treatment of diseases |
July 1, 2008 |
| This invention provides compounds represented by the structure of the general formula (A): ##STR00001## wherein L is a lipid or a phospholipid, Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol, Y is either nothing or a spacer group ranging in length from 2 t |
| 7378438 |
Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenge |
May 27, 2008 |
| The present invention relates to multifunctional .beta.-agonist compounds comprising a reactive oxygen species scavenger group and a nitric oxide donor, and their use for the treatment of respiratory diseases involving airway obstruction, such as asthma and chronic bronchitis. The invent |
| 7365247 |
Method of large scale mutagenesis in tomato plants |
April 29, 2008 |
| The present invention relates to a rapid and large-scale production of tomato mutants by utilizing a miniature tomato plant which can be crossed with tomato commercial plants. Mutations are induced in the miniature tomato cultivars and desired mutants are subsequently identified in the |
| 7351527 |
Immunizing fish against viral infection |
April 1, 2008 |
| The present invention provides the isolated causative agent of the disease affecting Cyprinus carpino and a method for its isolation. The invention further provides avirulent forms, e.g., live-attenuated form, inactivated form and genetically modified forms of the virus which may be used |
| 7345033 |
Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them |
March 18, 2008 |
| The present invention provides a compound of the following formula I: R.sup.3--NH--C(.dbd.X)--P(.dbd.O)OR.sup.1OR.sup.2 including pharmaceutically acceptable salts, solvates, hydrates and polymorphs of the compounds of formula I, as well as geometrical isomers and optically active f |
| 7305144 |
System and method for compressing the dynamic range of an image |
December 4, 2007 |
| A gradient domain compression system generates, from an input image having a high luminance dynamic range, an output image having a lower luminance dynamic range. The system comprises a gradient image generator module, a gradient compression module, and an output image generator module. |
| 7303760 |
Method for treating multi-drug resistant tumors |
December 4, 2007 |
| Methods for administering mitomycin C to a multi-drug resistant cell and for reducing the toxicity of the compound are described. In the methods, mitoymic C is provided in the form of a prodrug conjugate, where the drug is linked to a hydrophobic moiety, such as a lipid, through a cleava |
| 7297540 |
Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-o |
November 20, 2007 |
| Methods of generating, and isolating adult stem cells and utilizing such cells and/or embryonic stem cells in generating tissue of a specific function and micro-architecture are provided. |
| 7253341 |
Denaturant stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides |
August 7, 2007 |
| Novel denaturant-stable, protease resistant, homo-oligomeric proteins, also referred to herein as stable proteins (SPs), having chaperone-like activity; methods of production and purification of SPs; nucleic acids encoding SPs; methods of isolating nucleic acids encoding SPs; antibodies |
| 7238656 |
Protective factors against inflammation, burns and noxious stimuli |
July 3, 2007 |
| Peptide factors isolated from skin following exposure to chemical or thermal injury and treatment with iodine preparations are capable of reducing or ameliorating the extent of injury when administered to other animals. Specific peptides, including fragments of histone H2A and fibrin |
| 7232929 |
Amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid |
June 19, 2007 |
| The invention relates to new 2,2,3,3-tetramethylcyclopropane carboxamide derivative compounds, pharmaceutical compositions thereof and uses thereof for treating psychotic disorders, neurodegenerative diseases, epilepsy and pain. |
| 7223902 |
Method of producing recombinant Aspergillus niger .beta.-glucosidase and an aroma spreading plan |
May 29, 2007 |
| The invention provides a method of producing a recombinant polypeptide having .beta.-glucosidase enzymatic activity, a polynucleotide encoding the polypeptide, nucleic acid constructs carrying the polynucleotide, transformed cells, such as yeast cells, and transgenic organisms expres |
| 7223389 |
Compositions and methods for treatment of cancer |
May 29, 2007 |
| The present invention discloses lentogenic viral strains useful in the treatment of cancer. A preferred viral strain of Newcastle Disease Virus (NDV) is specifically characterized in terms of biological activities. The present invention further discloses treatment of cancer by applic |
| 7200318 |
Near infra-red composite polymer-nanocrystal materials and electro-optical devices produced ther |
April 3, 2007 |
| The invention comprises a composite material comprising a host material in which are incorporated semiconductor nanocrystals. The host material is light-transmissive and/or light-emissive and is electrical chargetransporting thus permitting electrical charge transport to the core of |
| 7189692 |
Synthetic peptides and pseudopeptides having osteogenic activity and pharmaceutical compositions |
March 13, 2007 |
| Cyclic to Synthetic pseudopeptide derivatives of osteogenic growth polypeptide (OGP) and OGP(10-14) which are capable of enhancing bone cell proliferation and bone formation. Pharmaceutical composition comprising as active ingredient at least one pseudopeptide derivative of the inven |
| 7189414 |
Controlled release oral drug delivery system |
March 13, 2007 |
| The invention relates to synchronous drug delivery composition comprising a polymeric matrix which comprises hydrogel blended with a hydrophobic polymer, so as to form an erodible matrix, a drug, and, optionally, an agent which enhances intestinal drug absorption and/or an agent which |
| 7189398 |
Broad spectrum pyrogenic exotoxins antagonists and vaccines |
March 13, 2007 |
| The invention relates to peptides having an amino acid sequence substantially homologous to an amino sequence of a domain of a pyrogenic exotoxin, which domain forms a central turn in the exotoxin starting within .beta.-strand 7 and connecting the .beta.-strand 7, via short .beta.-st |
| 7176498 |
Terahertz radiating device based on semiconductor coupled quantum wells |
February 13, 2007 |
| A semiconductor device and method of its fabrication are provided to enable the device operation in a THz spectral range. The device comprises a heterostructure including at least first and second semiconductor layers. The first and second layers are made of materials providing a qua |
| 7174459 |
Imprinting an identification certificate |
February 6, 2007 |
| A system and method for using imprinting as part of a security function that involves a user, for a security and/or identification mechanism. Imprinting is preferably used for cryptographic primitives, for determining a one-way function that operates at least partially according to a |
| 7172749 |
Radiolabeled irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and the |
February 6, 2007 |
| Radiolabeled epidermal growth factor receptor tyrosine kinase (EGFR-TK) irreversible inhibitors and their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for rad |
| 7141552 |
Use of lipid conjugates in the treatment of diseases |
November 28, 2006 |
| The invention provides a method for treating a subject suffering from an intestinal disease, including, inter alia, Crohn's disease, ulcerative colitis, immuno-inflammatory intestinal injury, drug-induced enteropathy and ischemia-induced intestinal injury. This invention further provides |
| 7135295 |
Detection of small molecules by use of a piezoelectric sensor |
November 14, 2006 |
| A protein comprising an antigen-binding portion formed by two cooperating peptide sequences of FIGS. 3A and 3B of the application. The protein may alternatively comprise an altered antigen-binding portion where at least one of the peptide sequences is an altered sequence, an altered sequ |
| 7122668 |
Platinum complexes and their use in therapy |
October 17, 2006 |
| The present invention concerns novel platinum complexes in which at least one of the amine ligand is a non-planar heterocyclic aliphatic amine. The platinum complexes may be in a trans or cis configuration and were found to posses therapeutic activites. Thus, the present concerns novel |
| 7115161 |
Ink-jet ink compositions based on oil-in-water microemulsion forming nanoparticles upon applicat |
October 3, 2006 |
| An Ink-jet ink composition for piezoelectric in-jet printing comprising: (a) a hydrophobic dye; (b) an oil-in-water microemulsion including: (i) a volatile oil; (ii) water; (iii) a co-solvent; (iv) at least one surfactant; and (v) a binder, wherein upon application of the ink to a su |
| 7109993 |
Method and system for the automatic computerized audio visual dubbing of movies |
September 19, 2006 |
| A method for automated computerized audio visual dubbing of a movie comprises (i) generating a three-dimensional head model of an actor in a movie, the head model being representative of specific facial features of the actor, and (ii) generating a three-dimensional head model of a dubber |
| 7101864 |
Compositions comprising oxophosphonate-based metalloproteinase inhibitors |
September 5, 2006 |
| The present invention relates to compositions useful for treating or controlling disease states or conditions associated with zinc containing proteinases, especially metalloproteinases. The active ingredient in these compositions is an alpha-oxo- or alpha-thixophosphpnate of formula |
| 7101859 |
Use of lipid conjugates in the treatment of diseases |
September 5, 2006 |
| The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE |
| 7101839 |
Methods of and compositions for inhibiting the proliferation of mammalian cells |
September 5, 2006 |
| A method of preventing, inhibiting and/or reversing proliferation, colonization, differentiation and/or development of abnormally proliferating cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease |
| 7090995 |
Molecules and methods using same for measuring non-transferrin bound iron |
August 15, 2006 |
| A molecule suitable for use as an indicator of free iron levels in a biological sample, the molecule including an iron binding moeity and a signal generating moeity, wherein an intensity of the signal generated by the signal generating moeity is related to an amount of the iron bound by |
| 7074915 |
Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof |
July 11, 2006 |
| The invention relates to an antisense oligonucleotide targeted to the coding region of the human acetylcholinesterase (AChE), which selectively suppresses the AChE-R isoform of the enzyme. The antisense oligonucleotide is intended for use in the treatment and/or prevention of neuromu |
