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William H. Rorer, Inc. Patents
Assignee:
William H. Rorer, Inc.
Address:
Fort Washington, PA
No. of patents:
145
Patents:


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Patent Number Title Of Patent Date Issued
4725686 Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including February 16, 1988
A method for increasing cardiotonic contractility in humans or other animals using a class of benzodiazinonepryidazinone and hydroxy-pyrazolyl compounds and pharmaceutical compositions including the same.
4692329 Erythromycin/benzoyl peroxide antiacne compositions September 8, 1987
Process and composition for the topical treatment of acne which comprises as ingredients a peroxide of an organic acid and an erythromycin compound selected from the group consisting of erythromycin and its stearate and glucoheptonate derivatives and in which said peroxide is from one-ha
4689335 Heterocyclic guanidines for treating gastrointestinal motility dysfunction August 25, 1987
A method for treating gastrointestinal motility dysfunctions using phenylheterocyclic guanidines and novel heterocyclic guanidine compounds.
4668673 Bicycle benzo-oxy heterocyclic ethers and thioethers, pharmaceutical compositions and use May 26, 1987
A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity
4666913 Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same May 19, 1987
A method for increasing cardiotonic contractility in humans or other animals using a class of hydroxy and aminothiazolyl-benzodiazinone compounds and pharmaceutical compositions including the same.
4647559 Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use March 3, 1987
A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity
4639442 Benzocyclobutene aminoalkylene ethers and thioethers, pharmaceutical compositions and use January 27, 1987
A class of benzocyclobutene aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity
4638001 Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use January 20, 1987
A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity
4637528 Articulated joint in aerosol medicament dispenser January 20, 1987
A sliding and pivoting joint, and a retractable medicament spray dispenser having such a joint. A sleeve is telescopically mounted on the dispenser housing by engaging a pair of pin-like projections on a pair of ears on the sleeve into slots which are in opposite side walls of the housin
4632927 Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses December 30, 1986
A class of bicyclic nitrogen heterocyclic ether and thioether compounds exhibiting pharmacological activity including cytoprotective, H.sub.2 -antagonist, anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment o
4612309 Antisecretory bicyclic benzo-oxy heterocyclic ethers and thioethers September 16, 1986
A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastro-intestinal hyperacidity
4611011 Amidinoureas for treating irritable bowel syndrome September 9, 1986
1-Phenyl-3N-alkyl amidinoureas are useful in the treatment of irritable bowel syndrome.
4605551 Dry oil coated antacid process August 12, 1986
This invention relates to an improvement comprising coating agitated particles of substantially anhydrous antacid with a solvent-free mixture of electronegatively charged material in a non-toxic inert substantially water insoluble oil.
4595683 3- and 5-[bicyclic ether or bicyclic alkylene thioether]alkylene amino thiatriazines, and their June 17, 1986
A class of 3- and 5-amino thiatriazine compounds exhibiting pharmacological activity, including gastrointestinal anti-ulcerogenic and cytoprotective activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcero
4593028 5-hetero aryl-substituted-2-pyridones useful as cardiotonic agents for treatment of congestive h June 3, 1986
Cardiotonic 5-heteroaryl-substituted-2-pyridone compounds, pharamaceutical compositions, and a method for the treatment of congestive heart failure.
4588719 Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use May 13, 1986
A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity
4565826 Heterocyclic amidinoureas January 21, 1986
This invention relates to a novel class of heterocyclic amidinourea and heterocyclic amidinothiourea compounds wherein the heterocyclic substitution is at the 1-N urea nitrogen atom. These compounds exhibit pharmaceutical activity and may be incorporated into pharmaceutical preparati
4564640 Amidinoureas substituted in both the urea and amidino nitrogen positions January 14, 1986
A method of inducing blood pressure reduction in humans and mammals by administering 2,6-disubstituted phenyl N-alkyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, acyloxy or halo acyloxy group and a novel class
4563475 Guanidine derivatives for treating gastrointestinal motility dysfunction January 7, 1986
A method for the treatment of a gastrointestinal motility dysfunction using a nitrogen containing heterocyclyl substituted acetylguanidine.
4563460 Quinoline and quinazoline derivatives for treating gastrointestinal motility dysfunctions January 7, 1986
A method for treating gastrointestinal motility dysfunctions using 2-amino-quinoline and -quinazoline derivatives.
4563456 1,2,4-Triazines for treating gastrointestinal motility dysfunction January 7, 1986
Method for treating gastrointestinal motility dysfunctions using 1,2,4-triazines.
4562209 Promotion of feed efficiency in animals December 31, 1985
Feed supplements, which increase the dwell time of ingested nutrient matter in the gastrointestinal tract of food producing animals, and which provide for increased digestion and absorption of ingested nutrient matter, are administered to food producing animals to increase feed efficienc
4562188 Triazinones for treating irritable bowel syndrome December 31, 1985
A method for the treatment of irritable bowel syndrome using a 1,3,5-triazin-2-one and a class of 6-amino and 6-mercaptyl-1,3,5-triazin-2-one compounds.
4544670 Method of treating coccidiosis with acyl guanidines October 1, 1985
Methods for the treatment of physiological disorders, including protozoal infections in mammalian and avian species and gastrointestinal and cardiovascular disorders in mammalian species by administering a class of aralkyl- and aralkenyl-acyl, and thioacyl, guanidine compounds, pharm
4543352 Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses September 24, 1985
A class of naphthalene aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ul
4539321 5-Diaza-aryl-3-substituted pyridone compounds September 3, 1985
5-Diaza-aryl-3-substituted-2-pyridone compounds useful for increasing cardiac contractility, pharmaceutical compositions and a method for the treatment of congestive heart failure comprising the use of said compounds.
4529723 Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use July 16, 1985
A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity
4520025 Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses May 28, 1985
A class of bicyclic nitrogen heterocyclic ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity a
4515718 Amidinoureas May 7, 1985
A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed.
4514400 Cardiotonic 5-heteroaryl-pyridone April 30, 1985
5-Heteroaryl-pyridone compounds, their pharmaceutical uses and a method of treating congestive heart failure are disclosed.
4496573 1-Pyridylmethyl-3-acyl guanidines January 29, 1985
1-Acyl-3-pyridyl guanidine and 1-acyl-3-pyridylalkyl guanidine compounds, methods for the treatment of blood pressure disorders, including hypertension, in humans and other mammals.
4487779 Substituted phenyl amidinoureas December 11, 1984
This invention relates to a method of lowering blood pressure in humans and mammals using 2,6-disubstituted phenyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, haloacyloxy, or acyloxy group and to novel 2,6-
4486439 Treatment of coccidiosis December 4, 1984
A method for the preventive and curative treatment of coccidial infections in humans and other animals comprising the administration thereto of an amidinourea of amidinothiourea.
4486405 Pigmented cosmetic vehicle containing a mixture of alkoxylated surfactants December 4, 1984
A spreadable, flowable and greaseless cosmetic coverup composition which includes a relatively large amount of pigment and a mixture of two alkoxylated surfactants.
4460585 1-Aryl-4-hydrazinyl-s-triazin-2-ones July 17, 1984
4452980 Triazinones June 5, 1984
Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thio
4446152 Method of treating congestive heart failure May 1, 1984
This invention relates to a composition and method of treating congestive heart failure in warm blooded animals, employing substituted phenylamidinourea compounds as the active agents.
4443456 Pyridyl alkylene amidinoureas April 17, 1984
This invention relates to a novel class of amidinourea and amidinothiourea compounds wherein the urea nitrogen atom is substituted by a heterocyclic alkylene group, and their use in pharmaceutical preparations which are useful for producing anti-ulcerogenic, antisecretory, antispasmodic,
4440949 Amidinoureas April 3, 1984
A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents.
4440765 Amidinoureas April 3, 1984
A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed.
4436911 Heterocyclic amidinoureas March 13, 1984
This invention relates to a novel class of heterocyclic amidinourea and heterocylic amidinothiourea compounds wherein the heterocyclic substitution is at the 1-N urea nitrogen atom. These compounds exhibit pharmaceutical activity and may be incorporated into pharmaceutical preparatio
4432979 Pyridone compounds February 21, 1984
Cardiotonic 5-heteroaryl-substituted-2-pyridone compounds, pharmaceutical compositions, and a method for the treatment of congestive heart failure.
4418209 Amidinothioureas November 29, 1983
This invention describes a new class of 1-amidino-3-phenylthiourea and N'-phenylamidinothiourea compounds wherein the phenyl group is ortho substituted, and processes for their preparation. The phenylamidinothiourea compounds may be incorporated into pharmaceutical preparations which
4406897 6-Aryl-4-hydrazinyl-s-triazin-2-ones September 27, 1983
4393077 1-Methylene-1-phenylguanidine compounds July 12, 1983
Compounds having the formula: ##STR1## wherein X.sub.1, X.sub.2, R, R.sub.1, R.sub.2 and R.sub.3 are as set forth hereinafter, their preparation and uses as ganglionic blocking agents are disclosed.
4388301 Method and composition for treating acne June 14, 1983
A method of treating skin conditions utilizing a deodorized composition containing soluble polysulfide compounds and the composition therefor.
4387225 Heterocyclic alkylene triazinones June 7, 1983
Heterocyclic alkyl s-triazine compounds are prepared from the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give respectively substituted s-triazinones and thiones of the formula ##STR1## which have pharmacological
4365093 Ethynylbenzene compounds and derivatives thereof December 21, 1982
Novel ethynylbenzene compounds and their derivatives which are useful for the treatment for the relief of inflammation, pain and fever.
4353842 Amidinoureas October 12, 1982
A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed.
4340609 Amidinourea derivative veterinary compositions for suppression of parasitemia July 20, 1982
Therapeutic compositions containing an amidinourea are used in the treatment of animals infested with blood residing parasites, particularly parasitic protozoal infestations of the blood and blood-forming organs.
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