| Patent Number |
Title Of Patent |
Date Issued |
| RE37379 |
High pressure gas exchanger |
September 18, 2001 |
| An apparatus 10 and method for delivering a high partial pressure of a gas into a liquid. The apparatus has a gas transfer device 12 with a housing 14 that includes upstream 16 and downstream 18 regions, between which there is located a gas-liquid contacting region 20 with contacting mem |
| 7402445 |
Method of forming micro-structures and nano-structures |
July 22, 2008 |
| Methods of forming a nano-structure for electron extraction are disclosed. One method of forming a nano-structure comprises irradiating an area on a first surface of a thermal conductive film to melt the area across the film. The film is insulated on a second surface to provide two-d |
| 7393855 |
2,2-bis-(hydroxymethyl)cyclopropylidenemethyl-purines and pyrimidines as antiviral agents |
July 1, 2008 |
| Compounds which are active against viruses have the following formulas: ##STR00001## wherein B is a purine or pyrimidine heterocyclic ring or base. In a preferred embodiment, the purine include 6-aminopurine (adenine), 6-hydroxypurine (hypoxanthine), 2-amino-6-hydroxypurine (guanine |
| 7387749 |
Method of delaminating aggregated particles with a coating agent in a substantially supercritica |
June 17, 2008 |
| The present invention involves a method of delaminating aggregated particles of natural silicate, nanoplatelet, nanofiber, or nanotube structures. The method comprises diffusing a coating agent in a substantially supercritical fluid between the aggregated particles and catastrophical |
| 7348645 |
Intelligent textile technology based on flexible semiconductor skins |
March 25, 2008 |
| A semiconductor-containing flexible skin suitable for use in intelligent textile applications includes a metal layer, an insulating layer, and one or more semiconductor islands sandwiched between a first flexible polymer layer and a second flexible polymer layer. Various electronics and |
| 7330396 |
Farfield analysis of noise sources |
February 12, 2008 |
| An algorithm diagnoses the noise source strength distribution on an arbitrarily shaped object based on acoustic pressures measured in the far field, known as FANS. FANS enable one to acquire a quick estimate of the acoustic pressure at locations that are off limit to traditional meas |
| 7294278 |
Method for oxygenating wastewater |
November 13, 2007 |
| A method and apparatus creates gas-enriched fluid that is used to treat wastewater. In one embodiment, the wastewater is withdrawn from a supply of wastewater to be treated, and the wastewater is delivered in an atomized manner to a vessel pressurized with gas to form gas-enriched wa |
| 7262845 |
Diffractive imaging spectrometer |
August 28, 2007 |
| A miniaturized diffractive imaging spectrometer (DIS) has a footprint less than 2.times.1 mm.sup.2, is about 2.5 mm tall (excluding an image detector, which in some embodiments may be a CCD matrix), and covers the entire visible spectral range from 400 nm to 700 nm with resolution of |
| 7247501 |
Imaging and targeting tumors using sickle cells |
July 24, 2007 |
| According to the present invention, there is provided a delivery vehicle including sickle red blood cells carrying a moiety. The moiety can be any type of diagnostic or therapeutic agent. The present invention further provides for a method of diagnosing systemic hypoxia, acidosis, or |
| 7241894 |
Antitumor agents |
July 10, 2007 |
| The invention provides compounds of formula I: ##STR00001## wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I |
| 7220727 |
Aminoglycosides as antibiotics |
May 22, 2007 |
| The present invention provides aminoglycosides and pharmaceutical compositions that include the aminoglycosides. The aminogylcosides are useful to treat or prevent infectious diseases (e.g., bacterial infections) in a mammal (e.g., human). |
| 7213445 |
Acoustic particulates density sensor |
May 8, 2007 |
| A technique for determining particulate density in a fluid monitors the changes in the speed of sound. Since the speed of sound is intimately related to the composites of the air mixture and since the speed of sound of clean air at any temperature and humidity can be calculated exactly, |
| 7199367 |
System and method for defect detection by inducing acoustic chaos |
April 3, 2007 |
| A defect detection system for thermally imaging a structure that has been energized by sound energy. The system includes a transducer that couples a sound signal into the structure, where the sound signal induces acoustic chaos in the structure that causes defects in the structure to |
| 7183268 |
2-amino-9-[(2-hydroxymethyl) cyclopropylidenemethyl] purine antiviral agents |
February 27, 2007 |
| Compounds which are active against viruses have the following Formulas: ##STR00001## wherein B is 2-aminopurine-9-yl, which may be unsubstituted or substituted in the 6 position with NHR.sub.1, OR.sub.2, or SR.sub.3; R.sub.1 is selected from the group consisting of alkyl, alkenyl, |
| 7157517 |
Method of delaminating a graphite structure with a coating agent in a supercritical fluid |
January 2, 2007 |
| The present invention involves a method of delaminating a graphite structure. The method comprises diffusing a coating agent in a supercritical fluid between layered particles of a graphite structure defining contacted graphite particles and catastrophically depressurizing the superc |
| 7144917 |
Inhibitors of matrix metalloproteinases |
December 5, 2006 |
| The invention provides compounds that inhibit MMPs; methods for treating or preventing cancer, angiogenesis, arthritis, connective tissue disease, cardiovascular disease, inflammation or autoimmune disease in a mammal; a method for inhibiting a matrix metalloproteinase in vivo or in vitr |
| 7122801 |
System and method for generating chaotic sound for sonic infrared imaging of defects in material |
October 17, 2006 |
| A defect detection system for thermally imaging a structure that has been energized by sound energy. The system includes a transducer that couples a sound signal into the structure, where the sound signal causes defects in the structure to heat up. In one embodiment, a hard metal disk is |
| 7109341 |
Therapeutic amides |
September 19, 2006 |
| The invention provides compounds of the formula: ##STR00001## wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt there |
| 7081341 |
Methods and compositions for the identification of antibiotics that are not susceptible to antib |
July 25, 2006 |
| Compositions and methods are provided to identify functional mutant ribosomes that may be used as drug targets. The compositions and methods allow isolation and analysis of mutations that would normally be lethal and allow direct selection of rRNA mutants with predetermined levels of |
| 7074272 |
Cubic (zinc-blend) aluminum nitride and method of making same |
July 11, 2006 |
| Device quality, single crystal film of cubic zinc-blende aluminum nitride (AlN) is deposited on a cubic substrate, such as a silicon (100) wafer by plasma source molecular beam epitaxy (PSMBE). The metastable zinc-blende form of AlN is deposited on the substrate at a low temperature by a |
| 7064332 |
Hand-held sound source for sonic infrared imaging of defects in materials |
June 20, 2006 |
| A hand-held sound source for use in an infrared or thermal imaging system that detects sub-surface defects in a structure. The sound source includes a transducer that is positioned against the structure to emit a sound signal into the structure. The sound source further includes an a |
| 7049337 |
Derivatives of 2-aminotetralins and pharmaceutical analogs thereof exhibiting differential CNS r |
May 23, 2006 |
| Aminotetralin derivatives and pharmacological analogs thereof which contain an N-propynyl group exhibit differential dopaminergenic receptor activity. The subject compounds are useful in affecting dopamine receptor activity, particularly in exhibiting differing activity among the various |
| 7043129 |
Wide bandgap semiconductor waveguide structures |
May 9, 2006 |
| A waveguide structure for transmitting broad spectrum light, includes a wide bandgap semiconductor thin film arranged on a substrate and ablated to form a waveguide channel to transmit the broad spectrum light. |
| 7008535 |
Apparatus for oxygenating wastewater |
March 7, 2006 |
| A method and apparatus creates gas-enriched fluid that is used to treat wastewater. In one embodiment, the wastewater is withdrawn from a supply of wastewater to be treated, and the wastewater is delivered in an atomized manner to a vessel pressurized with gas to form gas-enriched wa |
| 6998616 |
System and method for acoustic chaos and sonic infrared imaging |
February 14, 2006 |
| A defect detection system for thermally imaging a structure that has been energized by a sound energy. The system includes a transducer that couples a sound signal into the structure, where the sound signal causes defects in the structure to heat up. In one embodiment, a non-linear c |
| 6996481 |
Reconstruction of transient acoustic radiation from a finite object subject to arbitrarily time- |
February 7, 2006 |
| General algorithms are developed for reconstructing the acoustic field generated by an arbitrary object subject to an arbitrarily time-dependent excitation. These algorithms enable one to visualize a time-domain acoustic pressure wave as it travels through three-dimensional space. Su |
| 6995268 |
N- and O-substituted 4-[2-(diphenylmethoxy)-ethyl]-1- (phenyl) methyl) piperidine analogs and me |
February 7, 2006 |
| N- and O-substituted 4[2-diaromaticmethoxy and methylamino)alkyl]piperidin- es exhibit high CNS activity with respect to the dopamine transporter (DAT) and serotonin transporter (SERT). Preferred compounds exhibit highly differential behavior as between the DAT and SERT and between the |
| 6982332 |
Hybrid 2-aminotetralin and aryl-substituted piperazine compounds and their use in altering CNS a |
January 3, 2006 |
| Compounds exhibiting CNS activity in mammalian species, having the structure ##STR00001## wherein A is an optionally heterocyclic 5 or 6 membered aromatic ring system; ##STR00002## R.sup.2 is an organyl group substituent or two R.sup.2 together may form a fused ring system, o is an |
| 6958345 |
2-hydroxymethylcyclopropylidene methylpurines and -pyrimidines as antiviral agents |
October 25, 2005 |
| Compounds which are active against viruses have the following Formulas: ##STR1##wherein B is a purine or pyrimidine heterocyclic ring and is preferably selected from the group consisting of 6-aminopurine (adenine), 2,6-diaminopurine, 2-amino-6-azidopurine, 2-amino-6-cyclopropylaminop |
| 6935158 |
MIS hydrogen sensors |
August 30, 2005 |
| Hydrogen gas sensors employ an epitaxial layer of the thermodynamically stable form of aluminum nitride (AlN) as the "insulator" in an MIS structure having a thin metal gate electrode suitable for catalytic dissociate of hydrogen, such as palladium, on a semiconductor substrate. The |
| 6904806 |
Electronic intelligent indenter |
June 14, 2005 |
| An electronic intelligent indenter system that determines the hardness and the case depth of a hardened portion of a test part in a non-destructive manner. The system employs an electronic indenter tool having a tip. To determine the depth of the case hardened portion of the part, the in |
| 6897151 |
Methods of filling a feature on a substrate with copper nanocrystals |
May 24, 2005 |
| The invention relates to methods of making monodisperse nanocrystals comprising the steps of reducing a copper salt with a reducing agent, providing a passivating agent comprising a nitrogen and/or an oxygen donating moitey and isolating the copper nanocrystals. Moreover, the inventi |
| 6890552 |
Manufacturing therapeutic enclosures |
May 10, 2005 |
| Devices and methods for enhancing the healing of wounds, especially chronic wounds (e.g., diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a transplantable solid support (e.g., collagen-coated beads), and the keratinocyte-coated solid support |
| 6887297 |
Copper nanocrystals and methods of producing same |
May 3, 2005 |
| The invention relates to methods of making monodisperse nanocrystals comprising the steps of reducing a copper salt with a reducing agent, providing a passivating agent comprising a nitrogen and/or an oxygen donating moitey and isolating the copper nanocrystals. Moreover, the inventi |
| 6867219 |
Antitumor agents |
March 15, 2005 |
| The invention provides compounds of formula I: ##STR1##wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or |
| 6867194 |
Enzyme activated nitric oxide donors |
March 15, 2005 |
| Sugar-modified SIN-1 compositions are provided. The compositions are useful for generating NO in response to hydrolytic activity of a glycosidase specific for the O-glycosidic bond between the sugar and SIN-1 moieties. Pharmaceutical compositions containing the sugar-modified SIN-1 c |
| 6853075 |
Self-assembled nanobump array stuctures and a method to fabricate such structures |
February 8, 2005 |
| A self-assembled nanobump array structure including a semi-absorbing outer layer provided on at least one nanobump-forming substrate layer, the semi-absorbing outer layer configured to ablate slowly to allow an applied laser energy to be transmitted to the at least one nanobump-forming |
| 6848295 |
Acoustic wave sensor apparatus, method and system using wide bandgap materials |
February 1, 2005 |
| An acoustic wave sensor to detect an analyte, the sensor comprising a piezoelectric material including a wide bandgap semiconductor material grown using plasma source molecular beam epitaxy. |
| 6841153 |
Prevention of adhesions |
January 11, 2005 |
| Methods for the prevention of adhesion formation involve the administration of therapeutic formulations to a patient which include antibodies to TIMP-1 or TIMP-1 antisense oligonucleotides. The formulations can also include suitable carriers, such as a hyaluronic acid matrix, for optimal |
| 6828111 |
Three-dimensional in vitro model of human preneoplastic breast disease |
December 7, 2004 |
| A three-dimensional in vitro culture system comprising breast epithelial cells, endothelial cells and breast fibroblasts supports growth and functional differentiation of preneoplastic breast epithelial cells and endothelial cells and recapitulates estrogen induced in vivo effects on |
| 6790841 |
2-hydroxymethylcyclopropylidenemethylpurines and -pyrimidines as antiviral agents |
September 14, 2004 |
| Compounds which are active against viruses have the following Formulas: ##STR1##wherein B is a purine or pyrimidine heterocyclic ring and is preferably selected from the group consisting of 6-aminopurine (adenine), 2,6-diaminopurine, 2-amino-6-azidopurine, 2-amino-6-cyclopropylaminop |
| 6759659 |
Thermal imaging system for detecting defects |
July 6, 2004 |
| A thermal imaging system for detecting cracks and defects in a structure. An ultrasonic transducer is coupled to the structure through a malleable coupler. Ultrasonic energy from the transducer causes the defects to heat up, which is detected by a thermal camera. A control unit is employ |
| 6753360 |
System and method of preparing a reinforced polymer by supercritical fluid treatment |
June 22, 2004 |
| The present invention involves a method of preparing a reinforced polymer providing improved mechanical properties. The method includes providing particles of the layered silicate and a supercritical fluid. The method further includes mixing the layered silicate with a polymer to form a |
| 6747021 |
Cryptophycin compound |
June 8, 2004 |
| The present invention provides antitumor methods, formulations, and compounds comprising a cryptophycin. |
| 6737522 |
Chicken interleukin-15 and uses thereof |
May 18, 2004 |
| The present invention pertains to isolated DNA encoding avian interleukin-15 and to purified interleukin-15 polypeptides. |
| 6703415 |
Inhibitors of matrix metallaproteinases |
March 9, 2004 |
| The invention provides compounds that inhibit MMPs; methods for treating or preventing cancer, angiogenesis, arthritis, connective tissue disease, cardiovascular disease, inflammation or autoimmune disease in a mammal; a method for inhibiting a matrix metalloproteinase in vivo or in vitr |
| 6683451 |
Magnetic resonance force microscope for the study of biological systems |
January 27, 2004 |
| A high resolution magnetic resonance force microscope is adapted to study biological systems, such as isolated cells, sub-cellular organelles and other sub-cellular structures, or cellular receptors and proteins, at resolutions ranging from 1 micron to 1 .ANG.. The proposed magnetic |
| 6680311 |
Cryptophycin compounds |
January 20, 2004 |
| The present invention provides cryptophycin compounds of Formula I ##STR1##that are useful in the treatment of neoplasms. |
| 6676900 |
Method for the preparation and delivery of gas-enriched fluids |
January 13, 2004 |
| A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that |
| 6668190 |
Method and apparatus for activating molecules to stimulate neurological tissue |
December 23, 2003 |
| A drug delivery system includes a plurality of sites, a fluid channel for delivering a drug to one of the plurality sites, and a light channel for delivering light to an area near one of the plurality of sites. The fluid channel is a micro fluidic channel and the light channel is a wave |
