| Patent Number |
Title Of Patent |
Date Issued |
| 6847036 |
Charged particle beam detection system |
January 25, 2005 |
| A charged particle beam detection system (10) that includes a Faraday cup detector array (FCDA) for position-sensitive charged particle beam detection is described. The FCDA is combined with an electronic multiplexing unit (MUX) (2) that allows collecting and intgrating the charge de |
| 6845190 |
Control of an optical fiber scanner |
January 18, 2005 |
| Controls for an optical scanner, such as a single fiber scanning endoscope (SFSE) that includes a resonating optical fiber and a single photodetector to produce large field of view, high-resolution images. A nonlinear control scheme with feedback linearization is employed in one type of |
| 6842177 |
Macroblock padding |
January 11, 2005 |
| A boundary macroblock of a video object is padded without significant synchronization overhead between a host processor and an existing coprocessor. The host processor determines horizontal and vertical graphics primitives as a function of shape data stored in a host memory. The shap |
| 6835393 |
Enhanced transport using membrane disruptive agents |
December 28, 2004 |
| Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and a |
| 6833448 |
Annexin derivatives with endogenous chelation sites |
December 21, 2004 |
| Modified annexins having an N-terminal chelation site comprising an amino acid extension are disclosed. The amino acid extension includes an amino acid sequence X.sub.1 -Gly-X.sub.2, where X.sub.1 and X.sub.2 are selected from Gly and Cys, where at least one of X.sub.1 or X.sub.2 is Cys. |
| 6831745 |
Optical immersion probe incorporating a spherical lens |
December 14, 2004 |
| This invention provides a spherical lens optical immersion probe for use in analysis of solids, liquids, gases, powders, suspensions, slurries, particles and other homogeneous or heterogeneous samples. The use of a spherical lens in an optical immersion probe confers many advantages over |
| 6830729 |
Sample analysis instrument |
December 14, 2004 |
| The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spatially periodic channe |
| 6819460 |
Apparatus and methods for routing of optical beams via time-domain spatial-spectral filtering |
November 16, 2004 |
| Apparatus and methods are disclosed for spatially routing an optical pulse (data pulse) of an electromagnetic radiation and containing a specific address temporal profile and possibly additional data. Routing generally involves a unit of active material that is programmed using one or mo |
| 6814969 |
Immunologically significant herpes simplex virus antigens and methods for using same |
November 9, 2004 |
| The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are epitopes confirmed to be recognized by T-cells derived from herpetic lesions. T-cells having specificity for antigens of the invention have demonstrated cytotoxic |
| 6804771 |
Processor with register file accessible by row column to achieve data array transposition |
October 12, 2004 |
| A processor including a transposable register file. The register file allows normal row-wise access to data and also allows a transposed column-wise access to data stored in a column among registers of the register file. In transposed access mode, a data operand is accessed in a give |
| 6790341 |
Microband electrode arrays |
September 14, 2004 |
| The present invention provides microband electrode array sensors for detecting the presence and measuring the concentration of analytes in a sample. The microband electrodes of the invention have both a width and thickness of microscopic dimensions. Preferably the width and thickness of |
| 6785743 |
Template data transfer coprocessor |
August 31, 2004 |
| The template data transfer coprocessor (TDTP) offloads block data transfer operations from a mediaprocessor. A uni-block template, program-guided template, an indirect template and queue-based template are described. The TDTP includes a template interpreter that employs an event-driven c |
| 6782470 |
Operand queues for streaming data: A processor register file extension |
August 24, 2004 |
| The register file of a processor includes embedded operand queues. The configuration of the register file into registers and operand queues is defined dynamically by a computer program. The programmer determines the trade-off between the number and size of the operand queue(s) versus the |
| 6779101 |
Method and apparatus for processing compressed VLIW subinstruction opcodes |
August 17, 2004 |
| An area of on-chip memory is allocated to store one or more tables of commonly-used opcodes. The normal opcode in the instruction is replaced with a shorter code identifying an index into the table. As a result, the instruction is compressed. For a VLIW architecture, in which an inst |
| 6775404 |
Apparatus and method for interactive 3D registration of ultrasound and magnetic resonance images |
August 10, 2004 |
| Intraoperative ultrasound (US) is integrated with stereotactic systems, where a system interactively registers two-dimensional (2D) US and three-dimensional (3D) magnetic resonance (MR) images. The registration is based on tracking a US probe with a bC magnetic position sensor. A tra |
| 6767898 |
Methods for using specific saccharides for treating alzheimer's disease and other amyloidoses |
July 27, 2004 |
| A pharmaceutical agent for treating an amyloid disease in a patient, wherein the pharmaceutical agent comprises a glucose monosaccharide containing at least one anionic group, or a pharmaceutically acceptable salt thereof. The agent is directed to amyloid diseases in general and to A |
| 6759037 |
Compositions and methods for treating diabetes |
July 6, 2004 |
| The present invention provides an isolated population of cells containing an expressible nucleic acid encoding proinsulin containing a proinsulin cleavage site and a glucose-regulated expressible nucleic acid encoding a protease capable of cleaving the proinsulin cleavage site to produce |
| 6750448 |
Preparative separation of mixtures by mass spectrometry |
June 15, 2004 |
| The present invention provides an instrument and methods for the preparative separation of components of mixtures using mass spectrometric methods. Nondestructive ionization methods are employed to generate ionized components of a mixture, the ionized components are spatially separat |
| 6747780 |
Electrochromic organic polymer synthesis and devices utilizing electrochromic organic polymers |
June 8, 2004 |
| Large contrast ratio and rapid switching laminated electrochromic (EC) polymer device includes transparent electrode, cathodic EC polymer, gel electrolyte, and counter-electrode. Preferably the cathodic EC polymer is a poly(3,4-propylenedioxythiophene) derivative, PProDOT-Me.sub.2. C |
| 6734835 |
Patent scanned beam display with adjustable light intensity |
May 11, 2004 |
| In a scanning display apparatus an image signal source produces an image signal. A light emitter is coupled to the image signal source and responsive to the image signal to emit light. A lensing system receives light from the light emitter and passes exiting light. A scanner scans the |
| 6732247 |
Multi-ported memory having pipelined data banks |
May 4, 2004 |
| Multi-ported pipelined memory is located on a processor die serving as an addressable on-chip memory for efficiently processing streaming data. The memory sustains multiple wide memory accesses per cycle, clocks synchronously with the rest of the processor, and stores a significant p |
| 6731799 |
Object segmentation with background extraction and moving boundary techniques |
May 4, 2004 |
| Image data for an image frame are allocated among three groups. In one group are image data which are part of a derived motion boundary, along with image data which differ by at least a threshold amount from a corresponding point among normalized background data. In another group are |
| 6716184 |
Ultrasound therapy head configured to couple to an ultrasound imaging probe to facilitate contem |
April 6, 2004 |
| Method and apparatus for the simultaneous use of ultrasound on a probe for imaging and therapeutic purposes. The probe limits the effects of undesirable interference noise in a display by synchronizing high intensity focused ultrasound (HIFU) waves with an imaging transducer to cause |
| 6712925 |
Method of making a liquid analysis cartridge |
March 30, 2004 |
| The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spatially periodic channe |
| 6701310 |
Information search device and information search method using topic-centric query routing |
March 2, 2004 |
| An information search device capable of selecting topic search engines (i.e., search engines that focus on specific topics) that are appropriate to a user's search keywords when searching the Web on the Internet. Terms having relevance to each topic search engine are collected from, for |
| 6700552 |
Scanning display with expanded exit pupil |
March 2, 2004 |
| A display device is achieved using a simplified optical system which generates an expanded exit pupil without compromising magnification or resolution. Modulated light from a source is converged toward a focal point by an optics subsystem. A scanning subsystem deflects the converging |
| 6695147 |
Absorption-enhanced differential extraction device |
February 24, 2004 |
| This invention provides an extraction device and a method for extracting desired particles from a sample stream containing the desired particles. The device has a sample stream inlet, an extraction stream inlet, and an extraction channel in fluid communication with the sample stream inle |
| 6686202 |
Methods for detecting and extracting gold |
February 3, 2004 |
| Methods for detecting gold and quantitating gold in ore samples utilizing a gold-specific protein are provided, including methods for multiple sample handling. Also provided are methods for extracting gold from mineral suspensions utilizing a magnetic mineral binding reagent and gold-spe |
| 6686196 |
Recombinant, modified adenoviral vectors for tumor specific gene expression and uses thereof |
February 3, 2004 |
| This invention provides modified recombinant Ad vectors (e.g., AdE1- vectors) undergoing defined homologous recombination in order to create predictably rearranged genomic derivatives in a host cell. Genomic rearrangements can be achieved, for example, by incorporating two IR sequenc |
| 6682910 |
Human erythropoietin gene: high level expression in stably transfected mammalian cells |
January 27, 2004 |
| The Apa I restriction fragment of the human erythropoietin gene, for producing high titers of biologically active hormone from stably transfected cell lines. |
| 6681043 |
Interactive video object processing environment which visually distinguishes segmented video obj |
January 20, 2004 |
| A video processing environment includes a user interface and processing shell from which various video processing `plug-in` programs are accessed. The shell insulates the plug-ins from the intricacies of reading various file formats. The user interface allows an operator to load a video |
| 6678416 |
Detecting and segmenting local deformation in a tracked video object |
January 13, 2004 |
| A coarsely estimated object boundary is formed by a sequence of edge boundary points. A local affine transformation along the estimated object boundary is identified by analyzing edge energy of a current image frame. A sequence of edge boundary points which have edge energy change ratios |
| 6675286 |
Multimedia instruction set for wide data paths |
January 6, 2004 |
| Partitioned sigma instructions are provided in which processor capacity is effectively distributed among multiple sigma operations which are executed concurrently. Special registers are included for aligning data on memory word boundaries to reduce packing overhead in providing long data |
| 6674925 |
Morphological postprocessing for object tracking and segmentation |
January 6, 2004 |
| An object mask and a set of control points defined for a given frame are subjected to morphological processing to remove false edge points and provide a more robust mask for use in tracking the object in a next frame. The morphological processing is performed on a frame by frame basis |
| 6670194 |
Rapid quantitative analysis of proteins or protein function in complex mixtures |
December 30, 2003 |
| Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) co |
| 6666835 |
Self-cooled ultrasonic applicator for medical applications |
December 23, 2003 |
| A medical instrument uses solid tapered cones mounted to a preferably concave, spherically curved, piezoelectric ultrasound transducer which focuses and concentrates the ultrasound energy to a narrow tip so very high levels of ultrasound can be delivered to the tissue adjacent to the |
| 6664370 |
Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the |
December 16, 2003 |
| Methods for the detection, monitoring and treatment of malignancies in which the HER-2/neu oncogene is associated are disclosed. Detection of specific T cell activation (e.g., by measuring the proliferation of T cells) in response to in vitro exposure to the HER-2/neu protein, or det |
| 6656431 |
Sample analysis instrument |
December 2, 2003 |
| The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spatially periodic channe |
| 6639570 |
Retinal display scanning of image with plurality of image sectors |
October 28, 2003 |
| A scanning display produces an image having a plurality of image sectors for viewing by an eye. A first beam set is directed along a first beam path and modulated according to a first of the image sectors. A second beam set is directed along a second beam path and modulated according to |
| 6638520 |
Structures and methods for promoting vascularization |
October 28, 2003 |
| One aspect of the present invention provides implantable medical devices that comprise: (a) a device body; and (b) a surface layer attached to at least a portion of the device body, the surface layer comprising: (1) a surface layer body that defines an internal surface attached to the de |
| 6633309 |
Interactive video object processing environment having concurrently active subordinate windows |
October 14, 2003 |
| A video processing environment includes a user interface and processing shell from which various video processing `plug-in` programs are accessed. The shell insulates the plug-ins from the intricacies of reading various file formats. The user interface allows an operator to load a video |
| 6631256 |
Simplified high frequency tuner and tuning method |
October 7, 2003 |
| An RF tuner and tuning method employs analog quadrature mixing with a coarse-stepwise tunable local oscillator to a near-baseband passband region, followed by A/D conversion of the I and Q signals, correction of phase, group delay, and amplitude errors, image rejection, and translation |
| 6631240 |
Multiresolution video |
October 7, 2003 |
| A representation for encoding time varying image data that allows for varying spatial and temporal resolutions in different parts of a video sequence. The representation, called multiresolution video, is based on a sparse, hierarchical encoding of the video data as multiple streams. |
| 6631206 |
Image filtering in HSI color space |
October 7, 2003 |
| A method for filtering an angular signal which avoids errors in averaging and differencing operations. Components of a hue signal are separated into groups based upon the sign of a corresponding filter coefficient a.sub.i for the respective component and the range of the hue component va |
| 6629040 |
Isotope distribution encoded tags for protein identification |
September 30, 2003 |
| The present invention provides methods and reagents for identifying specific masses of compounds in a complex mixture. In particular, the present invention describes an isotope distribution encoded tag (IDEnT) concept wherein the ability to distinguish an analyte encoded with a non-n |
| 6607758 |
Methods for inhibiting and reducing amyloid fibril formation associated with Alzheimer's Disease |
August 19, 2003 |
| A method of inhibiting amyloid formation, deposition, accumulation, or persistence, or amyloid protein-amyloid protein interactions, amyloid-proteoglycan interactions, amyloid-PG/GAG interactions and/or amyloid-glycosaminoglycan interactions, and/or dissolving or disrupting pre-forme |
| 6602695 |
DNA polymerase mutant having one or more mutations in the active site |
August 5, 2003 |
| This invention provides a DNA polymerase that is a mutant form of a naturally occurring DNA polymerase, of which one or more amino acids in the active site are mutated. The DNA polymerase mutant of this invention is characterized by altered fidelity or altered enzymatic activity in c |
| 6584224 |
Template matching using correlative auto-predicative search |
June 24, 2003 |
| A template is analyzed to determine a step size for searching within a search area. First, the template is padded with pixels to increase its size. Cross-correlation between the padded template and the original template leads to identification of an effective step size. Step sizes for |
| 6582963 |
Simultaneous analyte determination and reference balancing in reference T-sensor devices |
June 24, 2003 |
| A reference T-sensor system is provided for detecting the presence and/or measuring the concentration of analyte particles in a sample stream. The system includes: a) a laminar flow channel; b) three or more inlets in fluid connection with the laminar flow channel for respectively conduc |
| 6576896 |
Electroosmotic fluidic device and related methods |
June 10, 2003 |
| The present invention provides a electroosmotic fluidic device and method for delivering analytes to an analyzer to obtain structural information for the analyte. The device and method are useful in identifying proteins by mass spectrometry. |
