| Patent Number |
Title Of Patent |
Date Issued |
| 7296318 |
Toothbrush employing an acoustic waveguide |
November 20, 2007 |
| A power toothbrush (10) is disclosed having a handle (15) containing a rechargeable battery (12), an ultrasonic drive circuit (14), a sonic component (16) such as a motor, and a control unit (18). The handle is connected to a toothbrush head (20) preferably having a plurality of bris |
| 7295724 |
Polymer based distributive waveguide sensor for pressure and shear measurement |
November 13, 2007 |
| According to embodiments of the present invention, a distributed pressure and shear stress sensor includes a flexible substrate, such as PDMS, with a waveguide formed thereon. Along the waveguide path are several Bragg gratings. Each Bragg grating has a characteristic Bragg wavelength th |
| 7292389 |
Circular extinction contrast imaging microscope |
November 6, 2007 |
| Systems and methods for producing circular extinction (CE) contrast images of anisotropic samples. Microscope systems for determining circular extinction (CE), the differential transmission of left and right circularly polarized light resulting from circular dichroism (CD) of an anis |
| 7282709 |
Charged particle beam detection system |
October 16, 2007 |
| A charged particle beam detection system that includes a Faraday cup detector array (FCDA) for position-sensitive charged particle beam detection is described. The FCDA is combined with an electronic multiplexing unit (MUX) that allows collecting and integrating the charge deposited |
| 7280016 |
Design of membrane actuator based on ferromagnetic shape memory alloy composite for synthetic je |
October 9, 2007 |
| A membrane actuator includes a magnetically actuatable membrane and a magnetic trigger. The membrane includes a shape memory alloy (SMA), and the magnetic trigger is configured to induce a martensitic transformation in the SMA, to produce a larger force than would be achievable with |
| 7276345 |
Method for identifying candidate compounds that bind to a human type IX adenylyl cyclase polypep |
October 2, 2007 |
| The invention relates to novel human adenylyl cyclase nucleic acid and amino acid sequences. Also provided are vectors, host cells, recombinant methods for making and using the novel molecules and methods for identifying compounds which bind to the adenylyl cyclase proteins. |
| 7271007 |
Microscale diffusion immunoassay |
September 18, 2007 |
| Methods and apparatuses are provided for determining presence and concentration of analytes by exploiting molecular binding reactions and differential diffusion rates. Analyte particles and binding particles are allowed to diffuse toward each other, and slowing of the diffusion front |
| 7268188 |
Reversible crosslinking method for making an electro-optic polymer |
September 11, 2007 |
| A crosslinkable second-order nonlinear optical polymer having one or more polarizable chromophore moieties, one or more diene moieties, and one or more dienophile or dienophile precursor moieties, wherein the diene and dienophile moieties are reactive to form 4+2 cycloaddition products; |
| 7267654 |
Focused shock-wave devices with direct wave cavitation suppressor |
September 11, 2007 |
| A reflector (14) reflects energy emitting from an energy source (16) and focuses and directs it to a target. An aperture stop or suppressor disk (18) is positioned between the energy source (16) and target. The outer periphery of the aperture stop or suppressor disk (18) is an irregular |
| 7258837 |
Microfluidic device and surface decoration process for solid phase affinity binding assays |
August 21, 2007 |
| This invention provides a microfluidic device for use in the detection of one or more analytes in a fluid using solid-phase affinity binding assays. The device offers a practical, easy-to-use, portable, inexpensive, robust analytical system for the parallel and quantitative detection |
| 7256923 |
Switchable window based on electrochromic polymers |
August 14, 2007 |
| Syntheses of a new blue EC monomer (ProDOT-MePro), and a new red EC monomer (ProDOP-Et2) are described. Two additional new types of EC monomers based on 3,4-alkylenedioxythiophene include fluorinated EC monomers and an EC monomer including silicon. EC polymer devices having more than |
| 7252236 |
Methods of driving a scanning beam device to achieve high frame rates |
August 7, 2007 |
| The present invention provides methods and systems for scanning an illumination spot over a target area. The present invention removes stored energy from a scanning element to stop the scanning element from vibrating and to substantially return the scanning element to its starting po |
| 7247703 |
Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the |
July 24, 2007 |
| Methods for the detection, monitoring and treatment of malignancies in which the HER-2/neu oncogene is associated are disclosed. Detection of specific T cell activation (e.g., by measuring the proliferation of T cells) in response to in vitro exposure to the HER-2/neu protein, or det |
| 7243060 |
Single channel sound separation |
July 10, 2007 |
| The speech of two or more simultaneous speakers (or other simultaneous sounds) conveyed in a single channel are distinguished. Joint acoustic/modulation frequency analysis and display tools are used to localize and separate sonorant portions of multiple-speakers' speech into distinct |
| 7234040 |
Program-directed cache prefetching for media processors |
June 19, 2007 |
| Data are prefetched into a cache from a prefetch region of memory, based on a program instruction reference and on compile-time information that indicates the bounds of the prefetch region, a size of a prefetch block, and a location of the prefetch block. If the program reference address |
| 7233710 |
Polymer based electro-optic scanner for image acquisition and display |
June 19, 2007 |
| According to embodiments of the present invention, an ultra high speed miniature image acquisition system based on a scanning light beam for use with clinical endoscopic imaging applications, for example, is disclosed. In one embodiment, the image acquisition system may include a horizon |
| 7232002 |
Apparatus for controlling rigidity of vehicle body |
June 19, 2007 |
| An apparatus for controlling the rigidity of vehicle body according to the present invention comprises a controller for controlling a buckling form, which controls the buckling form by adding to a member to be inputted to a collision load a lateral force in the direction substantially |
| 7230583 |
Scanned beam display with focal length adjustment |
June 12, 2007 |
| In a scanning display apparatus an image signal source produces an image signal. A light emitter is coupled to the image signal source and responsive to the image signal to emit light. A lensing system receives light from the light emitter and passes exiting light. A scanner scans th |
| 7229968 |
Peptides for the treatment of Alzheimer's disease and other beta-amyloid protein fibrillogenesis |
June 12, 2007 |
| A pharmaceutical composition comprising peptide AG73 Arg-Lys-Arg-Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg-Thr (SEQ ID NO:1). |
| 7226562 |
Liquid analysis cartridge |
June 5, 2007 |
| The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spatially periodic ch |
| 7221217 |
Self-bias and digitally tunable conduction angle circuits for a differential RF non-linear power |
May 22, 2007 |
| A differential RF non-linear power amplifier employing low-voltage transistors in a cascode configuration uses self-biasing solutions rather than external biasing techniques to overcome transistor breakdown problems. The self-biasing solution ensures that the cascode devices and driv |
| 7209141 |
Macroblock padding |
April 24, 2007 |
| A boundary macroblock of a video object is padded without significant synchronization overhead between a host processor and an existing coprocessor. The host processor determines horizontal and vertical graphics primitives as a function of shape data stored in a host memory. The shap |
| 7208475 |
Peptides for the treatment of Alzheimer's disease and other beta-amyloid protein fibrillogenesis |
April 24, 2007 |
| A pharmaceutical composition comprising peptide HA3G76 Tyr-Leu-Ser-Lys-Gly-Arg-Leu-Val-Phe-Ala-Leu-Gly (SEQ ID NO:8). |
| 7204972 |
Annexin derivatives with endogenous chelation sites |
April 17, 2007 |
| Modified annexins having an N-terminal chelation site comprising an amino acid extension are disclosed. The amino acid extension includes an amino acid sequence X.sub.1-Gly-X.sub.2, where X.sub.1 and X.sub.2 are selected from Gly and Cys, where at least one of X.sub.1 or X.sub.2 is Cys. |
| 7198798 |
Methods and devices for promoting endothelial morphogenesis |
April 3, 2007 |
| In one aspect the present invention provides methods for promoting endothelial morphogenesis. The methods of this aspect of the invention include the step of providing to one or more endothelial cells an amount of an osteoprotegerin sufficient to promote endothelial morphogenesis. Th |
| 7192693 |
Methods for photopatterning hydrogels |
March 20, 2007 |
| In one aspect, the invention provides methods for forming a photopatterned hydrogel. In some embodiments, the methods comprise the step of exposing a solution comprising a monomer, a crosslinking agent, and a photoinitiator to a pattern of light comprising a first and a second light |
| 7189961 |
Scanning beam device with detector assembly |
March 13, 2007 |
| The present invention provides scanning beam devices that have one or more detectors positioned within a housing of the device. The detector(s) may be disposed anywhere within the housing to receive light reflected from the target area. In one embodiment, an optical assembly of the devic |
| 7189699 |
Peptides for the treatment of Alzheimer's disease and other .beta.-amyloid protein fibrillogenes |
March 13, 2007 |
| A pharmaceutical composition comprising peptide TABLE-US-00001 A5G81 Ala-Gly-Gln-Trp-His-Arg-Val-Ser- (SEQ ID NO: 15) Val-Arg-Trp-Gly. |
| 7189698 |
Peptides for the treatment of Alzheimer's disease and other beta-amyloid protein fibrillogenesis |
March 13, 2007 |
| A pharmaceutical composition comprising peptide TABLE-US-00001 A4G82 Thr-Leu-Phe-Leu-Ala-His-Gly-Arg-Leu- (SEQ ID NO:11) Val-Phe-Met. |
| 7186020 |
Thermal interface material (TIM) with carbon nanotubes (CNT) and low thermal impedance |
March 6, 2007 |
| According to embodiments of the present invention, a very thin thermal interface material (TIM) is developed, which is composed of carbon nanotubes, silicon thermal grease, and chloroform. The carbon nanotubes and chloroform comprise the filler and the silicone thermal grease compris |
| 7183116 |
Methods for isolation and labeling of sample molecules |
February 27, 2007 |
| The invention provides methods for labeling a molecule by contacting a sample molecule with a solid support coupled to a chemical group comprising a cleavable functional group, one or more functional groups, and a reactive group for the sample molecule, under conditions allowing the |
| 7179614 |
Screening methods to identify compounds that modulate type I phosphodiesterase (PDE) activity |
February 20, 2007 |
| The present invention relates to novel methods of signal transduction in cells. In particular, the invention relates to signal transduction via a class of enzymes known as phosphodiesterase enzymes or PDEs. The invention also relates to a class of signaling molecules known as G-coupl |
| 7159782 |
Methods of driving a scanning beam device to achieve high frame rates |
January 9, 2007 |
| The present invention provides methods and systems for scanning an illumination spot over a target area. The present invention removes stored energy from a scanning element to stop the scanning element from vibrating and to substantially return the scanning element to its starting po |
| 7158141 |
Programmable 3D graphics pipeline for multimedia applications |
January 2, 2007 |
| A programmable graphics pipeline and method for processing multiple partitioned multimedia data, such as graphics data, image data, video data, or audio data. A preferred embodiment of the programmable graphics pipeline includes an instruction cache, a register file, and a vector fun |
| 7149666 |
Methods for modeling interactions between massively coupled multiple vias in multilayered electr |
December 12, 2006 |
| Analyzing interactions between vias in multilayered electronic packages that include at least two spaced-apart conducting planes, and multiple vias that connect signal traces on different layers. Voltages at active via ports are represented as magnetic ring current sources, which gen |
| 7148006 |
Screening methods to identify agents that selectively inhibit hepatitis C virus replication |
December 12, 2006 |
| The present invention relates to novel methods for identifying antiviral agents which selectively interfere with viral proteins that override the interferon(IFN)-induced cellular defense mechanisms against viral infection. In particular, the present invention relates to screening ass |
| 7148001 |
In vitro formation of congophilic maltese-cross amyloid plaques to identify anti-plaque therapeu |
December 12, 2006 |
| Co-incubation of an amyloid protein with sulfated macromolecules as a method for the formation of amyloid plaques. The amyloid protein may be the beta-amyloid protein or the prion protein or the like. Amyoid plaque formation in one embodiment proceeds in vitro and desirably produces |
| 7145333 |
High sensitivity atomic magnetometer and methods for using same |
December 5, 2006 |
| The present invention provides a high sensitivity atomic magnetometer and methods of measuring low intensity magnetic fields that relate to the use of an alkali metal vapor and a buffer gas; increasing the magnetic polarization of the alkali metal vapor thereby increasing the sensitivity |
| 7144960 |
Reversible crosslinking method for making an electro-optic polymer |
December 5, 2006 |
| A crosslinkable second-order nonlinear optical polymer having one or more polarizable chromophore moieties, one or more diene moieties, and one or more dienophile or dienophile precursor moieties, wherein the diene and dienophile moieties are reactive to form 4+2 cycloaddition products; |
| 7141676 |
Water soluble multi-biotin-containing compounds |
November 28, 2006 |
| Water-soluble discrete multi-biotin-containing compounds with at least three (3) biotin moieties are disclosed. The water-soluble biotin-containing compounds may additionally comprise one or more moieties that confer resistance to cleavage by biotinidase or that is cleavable in vitro |
| 7141429 |
Use of liquid junction potentials for electrophoresis without applied voltage in a microfluidic |
November 28, 2006 |
| This invention provides methods for using liquid junction potentials to control the transport of charged particles in fluid streams that are in laminar flow within microfluidic channels. Applications of the methods of this invention include sample preconditioning (removal of interfering |
| 7138389 |
Oral androgen therapy using modulators of testosterone bioavailability |
November 21, 2006 |
| This invention provides methods of treating a mammalian subject in need of androgen therapy by orally administering to the subject testosterone, a testosterone ester, or a testosterone precursor in an oil vehicle and by administering to the subject a modulator such as finasteride or |
| 7138259 |
PDEs and uses thereof |
November 21, 2006 |
| The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucl |
| 7136418 |
Scalable and perceptually ranked signal coding and decoding |
November 14, 2006 |
| A method and system for encoding and decoding an input signal in relation to the most perceptually relevant aspects of the input signal. A two-dimensional (2D) transform is applied to the input signal to produce a magnitude matrix and a phase matrix that can be inverse quantized by a |
| 7122342 |
Protease-activated receptor PAR4 (ZCHEMR2) |
October 17, 2006 |
| The present invention relates to polynucleotide and polypeptide molecules for PAR4, a novel member of the protease-activated receptor family. The polypeptides, and polynucleotides encoding them, mediate biological responses and/or cellular signaling in response to proteases. Protease |
| 7116963 |
Simplified high frequency tuner and tuning method |
October 3, 2006 |
| A disclosed method tunes a signal from a channelized spectrum having a predetermined channel spacing. A signal of interest having a predetermined maximum bandwidth is mixed with a local oscillator signal, which has a frequency that is an integer multiple of the channel spacing or one |
| 7115272 |
Compositions and methods for WT1 specific immunotherapy |
October 3, 2006 |
| Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise a WT1 polypeptide comprising an immunogenic portion of WT1, wherein said WT1 polypeptide comprises the polypeptide of SEQ ID NO:144. Such compositions |
| 7105580 |
Porous structures useful for growing living tissue, and methods of manufacture |
September 12, 2006 |
| In one aspect the present invention provides biodegradable, porous structures that each include a structural framework, wherein the structural framework includes: (a) a solidified mixture of polymer molecules and amino acid molecules, wherein at least some of the amino acid molecules |
| 7104056 |
Design of ferromagnetic shape memory alloy composites and actuators incorporating such materials |
September 12, 2006 |
| The present invention employs an optimized cross-sectional shape for a ferromagnetic shape memory alloy (FSMA) composite that is used in a spring-type actuator, an improved hybrid magnetic trigger for use in FSMA based actuators, an a FSMA composite based spring type actuator, an a F |
| 7094580 |
Methods for producing pure perlecan and other heparan sulfate proteoglycans |
August 22, 2006 |
| A method of perlecan isolation (from the EHS tumor) which produces "clean" (i.e. substantially "pure") perlecan is disclosed. Clean perlecan is thus produced in sufficient quantities for use in a number of different in vitro and in vivo assays. In addition, this isolation method exploits |
