| Patent Number |
Title Of Patent |
Date Issued |
| 7460979 |
Method and system for enhanced resolution, automatically-calibrated position sensor |
December 2, 2008 |
| A system and method for sensing position and/or displacement of a moving, substrate, ram, target, piston, encoder wheel or the like. The system includes a plurality of transducers for generating two sinusoidal signals in quadrature related to the position and displacement of the substrat |
| 7459440 |
Ocular tear growth factor-like protein |
December 2, 2008 |
| The present invention relates to a novel lacrimal gland protein (designated lacritin) and the nucleic acid sequences encoding that protein. Lacritin has activity as a growth factor on both human corneal epithelial cells and on the lacrimal acinar cells that produce it. Accordingly, o |
| 7442681 |
Method of inhibiting vascular permeability |
October 28, 2008 |
| The present invention provides a method of regulating vascular permeability. A peptide inhibitor of p21-activated kinase has been found to inhibit the increase in vascular permeability induced by several factors. The present invention further provides methods of identifying regulator |
| 7439383 |
Sodium channel blockers |
October 21, 2008 |
| The present invention is directed to novel phenytoin derivative compounds and the use of such compounds as sodium channel blockers. Such compositions have utility as anti-cancer agents and can be used to limit or prevent PCa growth and/or metastasis. |
| 7432301 |
Use of S-nitrosothiol signaling to treat disordered control of breathing |
October 7, 2008 |
| The present invention is directed to a method of treating disordered control of breathing including the treatment of apnea and hypoventilation associated with congenital or acquired brain stem abnormalities. Specifically the invention is directed to treating disordered control of bre |
| 7427606 |
Method to reduce inflammatory response in transplanted tissue |
September 23, 2008 |
| The present invention provides a therapeutic method for treating biological diseases that includes the administration of an effective amount of a suitable antibiotic agent, antifungal agent or antiviral agent in conjunction with an A.sub.2A adenosine receptor agonist. If no anti-path |
| 7424967 |
Method for manufacture of truss core sandwich structures and related structures thereof |
September 16, 2008 |
| An embodiment provides a method of constructing a cellular structure having nodes therein comprising: providing at least one truss layer comprised of at least one truss unit, at least one of the truss units being comprised of truss members; providing at least one panel in mechanical |
| 7419834 |
System for detection of nitrosylated proteins |
September 2, 2008 |
| The present invention describes a novel, simplified method for detecting and monitoring whether the presence of nitrosylated proteins, such as S-nitrosoproteins, in a biological sample using fluorescence detection. The present invention further describes a method which can both quantify |
| 7414078 |
Oral general anesthetics and metabolitically resistant anticonvulsants |
August 19, 2008 |
| The present invention is directed to novel themisone derivative compounds that have been modified to prevent the formation of the toxic metabolite, 2-phenyl-acrylamide. Compositions comprising such derivative compounds have activity as anesthetics and as neuroprotective agents. |
| 7413894 |
TAG-1 and TAG-2 proteins and uses thereof |
August 19, 2008 |
| The present invention is directed to a newly discovered gene family with multiple isoforms, designated TAG-1, TAG-2a, TAG-2b, TAG-2c, and TAG-3, nucleic acid sequences encoding those proteins, and antibodies generated against said proteins. The genes, proteins, and peptides described her |
| 7403814 |
Method, apparatus, and computer program product for assessment of attentional impairments |
July 22, 2008 |
| A method, apparatus, and computer useable medium that provides, among other things, a standardized test protocol for screening and evaluation of attentional impairment using EEG data. Further, the method, apparatus, and computer program product enhances existing psychological, behavioral |
| 7402136 |
Efficient ultrasound system for two-dimensional C-scan imaging and related method thereof |
July 22, 2008 |
| An ultrasound system and related method for forming 2D C-scan images and/or collecting 3D image data from 2D transducer arrays. The system including in part a 2D transducer array of elements, transmit voltage generation means for each element, a memory buffer with or part of channels |
| 7401643 |
Heat exchange foam |
July 22, 2008 |
| A method and an apparatus for the efficient transfer of heat utilizing micro heat pipes that include a cellular foam or interconnected cellular/truss network having hollow ligaments. A predetermined fraction of the internal volume of the hollow ligaments is filled with a carefully ch |
| 7396825 |
Agonists of A2A adenosine receptors for treatment of diabetic nephropathy |
July 8, 2008 |
| The present invention provides a therapeutic method for treating diabetic kidney disease, e.g., diabetic nephropathy that includes the administration of an effective amount of an A.sub.2A adenosine receptor agonist. Optionally, the method includes administration of a type IV PDE inhi |
| 7381471 |
Hybrid polymers for functional tuning of microfluidic device surfaces |
June 3, 2008 |
| The present invention is directed to improved microdevices and methods of manufacturing such devices. More particularly the present invention is directed to the use of a compound having the general structure (formula (I)): wherein R is selected from the group consisting of C.sub.1-C.sub. |
| 7378400 |
Method to reduce an inflammatory response from arthritis |
May 27, 2008 |
| The present invention provides a therapeutic method for treating an inflammatory response caused by autoimmune stimulation, comprising the administration to a patient in need thereof of an antiinflammatory amount amount of an A.sub.2A adenosine receptor agonist. The autoimmune stimul |
| 7378094 |
Therapeutic uses of complement receptor 2 |
May 27, 2008 |
| The present invention is directed to an immune complex composition, and a method of using that complex to enhance an in viva immune response against a preselected target antigen. The immune complexes of the present invention comprise a monoclonal antibody specific for binding to comp |
| 7347825 |
Device and method for assessing asthma and other diseases |
March 25, 2008 |
| Device and method for non-invasively monitoring asthma and other respiratory diseases, as well as non-respiratory diseases. The method includes collecting condensate from a subject's breath, testing the condensate to determine its acetic acid/acetate level or concentration, and evalu |
| 7323542 |
Bone targeting peptides |
January 29, 2008 |
| The present invention relates to compositions comprising unique bone targeting peptides and the use of compositions comprising such peptides to induce bone repair and treat bone related diseases. |
| 7320870 |
Ocular tear growth factor-like protein |
January 22, 2008 |
| The present invention relates to a novel lacrimal gland protein (designated lacritin) and the nucleic acid sequences encoding that protein. Lacritin has activity as a growth factor on both human corneal epithelial cells and on the lacrimal acinar cells that produce it. Accordingly, o |
| 7315377 |
System and method for remote sensing and/or analyzing spectral properties of targets and/or chem |
January 1, 2008 |
| A method and a low-cost, robust and simple system for remote sensing and analyzing spectral properties of targets as a means to detect and identify them is introduced. The system can be highly portable but is usable in fixed locations or combination thereof. An aspect of the method a |
| 7288326 |
Active energy absorbing cellular metals and method of manufacturing and using the same |
October 30, 2007 |
| Multifunctional cellular metals (or other materials) for structural applications that are capable of recovering their original (undeformed) shape and thickness after impact or crushing (i.e., self-healing). Alternatively, they may normally be stored or used in their compressed (i.e., |
| 7261511 |
Robotic pick up and delivery system |
August 28, 2007 |
| A pick up and delivery system for use with mobile robots which have a body with a horizontal upper surface and at least one vertical side. The robot has at least one shelf, each of which contains a stop bar containing a retaining device. The system further uses multiple stations, each of |
| 7255858 |
Enhancing the efficacy of immunotherapies by supplementing with complement |
August 14, 2007 |
| The present invention is directed to a composition and method for enhancing the complement-mediated cytotoxicity of therapeutic antibodies for their target cells (i.e. those cells displaying the target epitope). More particularly the present invention enhances the efficacy of such th |
| 7241790 |
Compounds active in spinigosine 1-phosphate signaling |
July 10, 2007 |
| The present invention relates to S1P analogs that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds have the general structure of Formula (I) wherein R.sub.11 is C.sub.5 C |
| 7230073 |
Sperm specific proteins |
June 12, 2007 |
| The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications. |
| 7229258 |
Streamlined unobstructed one-pass axial-flow pump |
June 12, 2007 |
| A blood pump has an impeller rotatably disposed and magnetically suspended within a cavity of a stator by a plurality of magnetic bearings (passive permanent and active electromagnetic) having impeller magnets on the impeller and stator magnets or coils/poles on the stator. A motor i |
| 7226913 |
Pharmaceutical compositions having A.sub.2A adenosine receptor agonist activity |
June 5, 2007 |
| The present invention provides compositions for oral administration of compounds having A.sub.2A adenosine receptor agonist activity. These compositions are useful for treatment of inflammatory conditions. |
| 7223325 |
Method for orthogonal analyte stacking/injection systems in electrophoresis |
May 29, 2007 |
| In the present capillary electrokinetic chromatograpy method, analytes are injected by electroosmotic flow directly from a sample matrix into a separation buffer containing an electrokinetic vector with an opposite mobility. Analytes can now be injected at the velocity of electroosmotic |
| 7214665 |
2-propynyl adenosine analogs having A.sub.2A agonist activity and compositions thereof |
May 8, 2007 |
| The invention provides compounds having the following general formula (I): ##STR00001## wherein X, R.sup.1, R.sup.2, R.sup.7 and Z are as described here. |
| 7211348 |
Multifunctional battery and method of making the same |
May 1, 2007 |
| Disclosed herein is a multifunctional battery for supplying power to an electrical circuit, and the related method of making the same. Use of the multifunctional battery permits structural integrity and versatility, while maximizing power output of the cells and minimizing the overall |
| 7174200 |
Optimized high-speed magnetic resonance imaging method and system using hyperpolarized noble gas |
February 6, 2007 |
| A system and method for using hyperpolarized noble gases together with an appropriately designed and optimized magnetic resonance imaging pulse sequence to rapidly acquire static or dynamic magnetic resonance images. The strong magnetic resonance signal from hyperpolarized gases, combine |
| 7172760 |
Compositions and methods for prevention and treatment of uncontrolled formation of intravascular |
February 6, 2007 |
| Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers. |
| 7169818 |
Lysophosphatidic acid receptor agonists and antagonists |
January 30, 2007 |
| The present invention is directed to compositions comprising lysophosphatidic acid analogs and methods of using such analogs as agonist or antagonists of LPA receptor activity. In addition the invention is directed to LPA receptor agonists that vary in the degree of selectivity at in |
| 7164268 |
Method and apparatus for spin-echo-train MR imaging using prescribed signal evolutions |
January 16, 2007 |
| A magnetic resonance imaging "MRI" method and apparatus for lengthening the usable echo-train duration and reducing the power deposition for imaging is provided. The method explicitly considers the t1 and t2 relaxation times for the tissues of interest, and permits the desired image |
| 7157480 |
Use of pramipexole to treat amyotrophic lateral sclerosis |
January 2, 2007 |
| The present invention is directed to compositions comprising pramipexole and the use of such compositions to treat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). As shown in FIG. 6B the mean +/- SEM serum 2,3-DHBA levels for the 12 ALS participants decreased |
| 7129057 |
Human testis specific serine/threonine kinase 3 |
October 31, 2006 |
| The present invention relates to a family of testis specific kinases (the tssk family), nucleic acid sequences encoding those kinases and antibodies against the kinases. The invention is further directed to the use of thise kinases as targets for isolating specific inhibitors or anag |
| 7125550 |
Human sperm specific lysozyme-like proteins |
October 24, 2006 |
| The present invention relates to two novel, testis-specific proteins (C19 and C23) that arc lysozyme paralogues. The proteins are believed to play a role in capacitation of sperm and the fertilization of the ovum. Therefore these compounds make ideal targets for the design of contrac |
| 7094547 |
Sperm specific proteins |
August 22, 2006 |
| The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications. |
| 7067020 |
Bulk-solidifying high manganese non-ferromagnetic amorphous steel alloys and related method of u |
June 27, 2006 |
| Iron based amorphous steel alloy having a high Manganese content and being non-ferromagnetic at ambient temperature. The bulk-solidifying ferrous-based amorphous alloys are multicomponent systems that contain about 50 atomic percent iron as the major component. The remaining composit |
| 7064217 |
Agonists and antagonists of sphingosine-1-phosphate receptors |
June 20, 2006 |
| The present invention relates to S1P analogs that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds have the general structure (I), wherein R.sub.1 is C.sub.8 C.sub.22 alk |
| 7034533 |
Method and system for rapid magnetic resonance imaging of gases with reduced diffusion-induced s |
April 25, 2006 |
| A methodology, system and computer program product for designing and optimizing a rapid magnetic resonance imaging pulse sequence for creating images of a gas or gas-filled structure with substantially reduced diffusion-induced signal attenuation during the course of data acquisition |
| 7026358 |
Oral general anesthetics and metabolitically resistant anticonvulsants |
April 11, 2006 |
| The present invention is directed to novel themisone derivative compounds that have been modified to prevent the formation of the toxic metabolite, 2-phenyl-acrylamide. Compositions comprising such derivative compounds have activity as anesthetics and as neuroprotective agents. |
| 7026167 |
Systems and methods for the analysis of protein phosphorylation |
April 11, 2006 |
| The present invention relates to a method of applying mass spectrometry to analyzing peptides or proteins, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of protein/peptide phosphorylation wherein the side ch |
| 7025425 |
Method, system, and computer program product for the evaluation of glycemic control in diabetes |
April 11, 2006 |
| A method, system, and computer program product related to the diagnosis of diabetes, and is directed to predicting the long-term risk of hyperglycemia, and the long-term and short-term risks of severe hypoglycemia in diabetics, based on blood glucose readings collected by a self-moni |
| 7019112 |
Peptides recognized by melanoma-specific A1-, A2- and A3-restricted cytoxic lymphocytes, and use |
March 28, 2006 |
| Melanoma-specific, A1- and A3-restricted CTL epitopes have been identified in tyrosinase and pMel-17, respectively, and may be used in the design of vaccines. |
| 7014889 |
Process and apparatus for plasma activated depositions in a vacuum |
March 21, 2006 |
| Plasma deposition apparatus (1) and method that allows metal or nonmetal vapor (6) to be generated by electron-beam evaporation, guides that vapor using a noble gas stream (containing reactive gases in cases of reactive evaporation), ionizes the dense directed gas and vapor stream at wor |
| 6962988 |
Egg specific surface proteins |
November 8, 2005 |
| The present invention relates to proteins that are expressed in oocytes, nucleic acid sequences encoding those proteins and antibodies generated against those proteins. Composition and methods are provided for using the disclosed oocyte proteins as targets for contraceptive drugs. |
| 6946475 |
Anticancer calcium channel blockers |
September 20, 2005 |
| The present invention is directed to compounds useful as cancer cell inhibitors, compositions containing such compounds and methods for inhibiting proliferation of electrically non-excitable cells. |
| 6946275 |
Human testis specific serine/threonine kinase 1 and 2 |
September 20, 2005 |
| The present invention relates to a family of testis specific kinases (the tssk family), nucleic acid sequences encoding those kinases and antibodies against the kinases. The invention is further directed to the use of those kinases as targets for isolating specific inhibitors or antagoni |
