| Patent Number |
Title Of Patent |
Date Issued |
| PP18292 |
Dogwood tree named `Missy's Appalachian Morning` |
December 11, 2007 |
| A new distinct cultivar of dogwood, Cornus florida L., named `Missy's Appalachian Morning`, is provided. This cultivar is characterized by producing fruit with seeds that will not germinate after industry standard cold/moist stratification for 4 months. |
| PP18238 |
Dogwood tree named `Appalachian Joy` |
November 20, 2007 |
| A new distinct cultivar of dogwood, Cornus florida L., named `Appalachian Joy`, is provided. This cultivar is characterized by resistance to powdery mildew, which is superior to most other cultivars of flowering dogwood and similar to `Karen's Appalachian Blush` (U.S. Plant Pat. No. |
| 7427135 |
Adaptive photoscreening system |
September 23, 2008 |
| Briefly described, one embodiment of the system, among others, can be implemented as follows. The system includes a computer control system and an environmental light source that is controlled by the computer control system such that an amount of light provided by the environmental light |
| 7422869 |
Method for diagnosing infectious diseases |
September 9, 2008 |
| A method for diagnosing the presence in an animal of an infection due to a microorganism in which a test sample obtained from the animal is exposed to a population of the microorganism and the presence of binding of the microorganism by an antibody in the test sample is determined. |
| 7402316 |
Group A streptococcal vaccines |
July 22, 2008 |
| The present invention provides methods for eliciting an immune response against Group A streptococci, comprising use of recombinant fusion polypeptides, and compositions thereof, that include a multivalent immunogenic portion of at least two immunogenic polypeptides from Group A stre |
| 7370589 |
Systems and methods for fluid dispensing |
May 13, 2008 |
| Systems and methods are disclosed for dispensing fluids. The systems can include a sensor operable to detect when an object passes a first location as the object moves to a second location. The systems can also include a fluid dispenser operable to dispense fluid at the second locati |
| 7300792 |
Lux expression in eukaryotic cells |
November 27, 2007 |
| The luxA, B, C, D, and E genes from Photorhabdus luminescens have been introduced into Saccharomyces cerevisiae bioluminescent yeast cells. |
| 7276350 |
Method for diagnosing infectious diseases |
October 2, 2007 |
| A method for diagnosing the presence in an animal of an infection due to a microorganism in which a test sample obtained from the animal is exposed to a population of the microorganism and the presence of binding of the microorganism by an antibody in the test sample is determined. |
| 7272612 |
Method of partitioning data records |
September 18, 2007 |
| A tree-structured index to multidimensional data is created using occurring patterns and clusters within the data which permit efficient search and retrieval strategies in a database of DNA profiles. A search engine utilizes hierarchical decomposition of the database by identifying c |
| 7270827 |
Multivalent streptococcal vaccine compositions and methods for use |
September 18, 2007 |
| Compositions and methods for making and using therapeutic formulations of multivalent hybrid polypeptides comprising immunogenic peptides of M proteins from various different serotypes of group A streptococci and antibodies thereto are provided. Also provided are nucleic acids encoding |
| 7255863 |
Group A streptococcal vaccines |
August 14, 2007 |
| The present invention provides methods for eliciting an immune response against Group A streptococci, comprising use of recombinant fusion polypeptides, and compositions thereof, that include a multivalent immunogenic portion of at least two immunogenic polypeptides from Group A stre |
| 7253210 |
Methylene-bridged selective androgen receptor modulators and methods of use thereof |
August 7, 2007 |
| This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity o |
| 7250284 |
Destabilized bioluminescent proteins |
July 31, 2007 |
| Purified nucleic acids, vectors and cells containing a gene cassette encoding at least one modified bioluminescent protein, wherein the modification includes the addition of a peptide sequence. The duration of bioluminescence emitted by the modified bioluminescent protein is shorter |
| 7241774 |
Substituted tetrahydroisoquinoline compounds, methods of making, and their use |
July 10, 2007 |
| The present invention relates to novel substituted tetrahydroisoquinoline compounds, pharmaceutical compositions containing the compounds, methods of making the compounds, and methods of using the compounds to destroy a target cell, such as a cancer cell, and to treat or prevent a cancer |
| 7214693 |
Heterocyclic selective androgen receptor modulators and methods of use thereof |
May 8, 2007 |
| This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity o |
| 7205437 |
Selective androgen receptor modulators |
April 17, 2007 |
| The present invention relates to androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity, which are nonsteroidal ligands for the androgen receptor. The selective androgen receptor modulators (SARM) are useful for a) male contraception; b) treatmen |
| 7169942 |
Cannabinoid derivatives, methods of making, and use thereof |
January 30, 2007 |
| 1'-substituted cannabinoid derivatives of delta-8-tetrahydrocannabinol, delta-9-tetrahydrocannabinol, and delta-6a-10a-tetrahydrocannabinol that have affinity for the cannabinoid receptor type-1 (CB-1) and/or cannabinoid receptor type-2 (CB-2). Compounds having activity as either ago |
| 7129377 |
Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer |
October 31, 2006 |
| The present invention relates to an androgen receptor alkylating compound, wherein the compound may include, inter alia, an active functional group, which permits the alkylation of the androgen receptor. |
| 7105832 |
Composite solid-state scintillators for neutron detection |
September 12, 2006 |
| Applicant's present invention is a composite scintillator for neutron detection comprising a matrix material fabricated from an inorganic sol-gel precursor solution homogeneously doped with a liquid scintillating material and a neutron absorbing material. The neutron absorbing materi |
| 7097662 |
In-vivo orthopedic implant diagnostic device for sensing load, wear, and infection |
August 29, 2006 |
| A device for providing in vivo diagnostics of loads, wear, and infection in orthopedic implants having at least one load sensor associated with the implant, at least one temperature sensor associated with the implant, at least one vibration sensor associated with the implant, and at leas |
| 7074416 |
Antigen of hybrid M protein and carrier for group A streptococcal vaccine |
July 11, 2006 |
| Recombinant hybrid streptococcal M protein antigens are provided which elicit protective antibodies against Group A streptococci and prevent rheumatic fever. Recombinant hybrid genes which encode the antigen are provided. Vaccine compositions and methods of administering the composit |
| 7067321 |
Polyglutamine repeat sequences |
June 27, 2006 |
| Several neurodegenerative diseases result from the aggregation of polyglutamine repeat proteins into insoluble neuronal intranuclear inclusions. The invention provides methods with which to study the processes of these diseases, including methods for solubilizing polypeptides contain |
| 7063850 |
Protective antigen of group A Streptococci |
June 20, 2006 |
| The present invention provides the discovery of a new Streptococcus protective antigen (herein designated Spa) which has been identified and isolated from Streptococci. Spa is a surface antigen distinct from M protein which evokes opsonic antibodies that are protective against multip |
| 7041859 |
Method for halogenating or radiohalogenating a chemical compound |
May 9, 2006 |
| A method for obtaining a halogenated organic compound, whereby an organotrifluoroborate compound is reacted with a halide ion in the presence of an oxidizing agent to produce the corresponding halogenated organic compound. The method may be used for producing radiohalogenated organic |
| 7026500 |
Halogenated selective androgen receptor modulators and methods of use thereof |
April 11, 2006 |
| This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity o |
| 7022870 |
N-bridged selective androgen receptor modulators and methods of use thereof |
April 4, 2006 |
| This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity o |
| 7020560 |
Methods for cell-based combinatorial logic |
March 28, 2006 |
| A method for cell-based combinatorial logic includes the steps of providing at least one genetically engineered cell, the genetically engineered cell having at least one transcriptional unit. The transcriptional unit includes a gene and a promoter, wherein application of a stimulus t |
| 6998500 |
Selective androgen receptor modulators and methods of use thereof |
February 14, 2006 |
| This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity o |
| 6967067 |
Patterning methods and systems using reflected interference patterns |
November 22, 2005 |
| A method for patterning a layer on a substrate can include projecting coherent radiation toward a reflector surface so that the coherent radiation is reflected off the reflector surface to provide a holographic projection of a desired image wherein the reflector surface includes info |
| 6960346 |
Vehicles for delivery of biologically active substances |
November 1, 2005 |
| A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers. Methods for making and using are disclosed, as are kits for administration of the pharmaceutica |
| 6951935 |
Heteroatom-substituted porphyrins and methods for synthesis of same |
October 4, 2005 |
| Novel methods of synthesizing heteroatom-containing porphyrins and metalloporphyrins are disclosed. Novel heteroatom-containing porphyrin and metalloporphyrin compounds are also disclosed. The new methods advantageously utilize metal-catalyzed cross-coupling and amination reactions t |
| 6936637 |
Prevention of apoptosis in non-cancerous cells |
August 30, 2005 |
| Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is observed to a lesser extent, in simila |
| 6916852 |
Method for regulation of microvascular tone |
July 12, 2005 |
| Methods and kits for regulating arterial microvascular tone in which a COX-2 inhibitor and a cannabinoid receptor agonist are co-administered to a subject. |
| 6875757 |
LPA receptor agonists and antagonists and methods of use |
April 5, 2005 |
| The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such metho |
| 6838484 |
Formulations comprising selective androgen receptor modulators |
January 4, 2005 |
| The present invention relates to pharmaceutical compositions and formulations comprising a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subclass |
| 6730443 |
Patterning methods and systems using reflected interference patterns |
May 4, 2004 |
| A method for patterning a layer on a substrate can include projecting coherent radiation toward a reflector surface so that the coherent radiation is reflected off the reflector surface to provide a holographic projection of a desired image wherein the reflector surface includes info |
| 6716433 |
Group a streptococcal vaccines |
April 6, 2004 |
| The present invention provides immunogenic synthetic fusion polypeptide which stimulates an immune response against a selected pathogen, comprising at least two immunogenic polypeptides from a Group A streptococci of at least 10 amino acids in length which are capable of stimulating |
| 6696279 |
Purified and isolated Mat II .beta. subunit nucleic acids and polypeptides and therapeutic and s |
February 24, 2004 |
| MAT II .beta. subunit proteins and cDNAs encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to MAT II .beta. subunit homologs, and methods of producing th |
