| Patent Number |
Title Of Patent |
Date Issued |
| D402824 |
Podium |
December 22, 1998 |
|
| 7410472 |
Articulating joint |
August 12, 2008 |
| The present invention pertains to an articulating joint that is disengageable between two modes of operation: unidirectional movement of the joint or bi-directional movement of the joint, with features that allow the mode to be automatically switched as required. When fully locked, t |
| 7371533 |
Methods for separation of polymeric compounds |
May 13, 2008 |
| Recently two techniques using free solution electrophoresis to separate charged-uncharged polymer conjugates have proven successful: End Labeled Free Solution Electrophoresis (ELFSE) for DNA sequencing, and Free Solution Conjugate Electrophoresis (FSCE) for molar mass profiling of un |
| 7235372 |
Use of neuronal apoptosis inhibitor protein (NAIP) |
June 26, 2007 |
| The invention provides a novel NAIP nucleic and sequences. Also provided are anti-NAIP antibodies and methods for modulating apoptosis and detecting compounds which modulate apoptosis. |
| 7192580 |
Purging of cells using viruses |
March 20, 2007 |
| The subject invention relates to viruses that are able to purge (reduce or eliminate) undesirable cells in a mixture of cells. Undesirable cells can include neoplastic cells, cells mediating graft-versus host diseases, and autoimmune cells. The subject invention also relates to the purgi |
| 7183279 |
Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof |
February 27, 2007 |
| The invention relates to new basic amino acid derivatives of general formulae I, II and III, and the preparation and use thereof in treatment of pain. The compounds have histogranin-like antinociceptive, morphine potentiating and COX-2 induction modulating activities. ##STR00001## wh |
| 7127136 |
Optical crossbar switch |
October 24, 2006 |
| An optical crossbar switch comprises a plurality of input devices (1A to 1C), a plurality of output devices (2A to 2C), an optical transpose system (3) positioned between the input devices and the output devices, and control means for controlling the interconnections between the input |
| 7094898 |
Ruthenium compounds, their production and use |
August 22, 2006 |
| A new class of compounds is disclosed that in preferred embodiments relate to Ru-based catalysts suitable for use in olefin metathesis reactions. Such compounds demonstrate high rates of catalytic turnover in comparison with other Ru catalysts known in the art. Moreover, the catalysts ar |
| 7074786 |
Histogranin-like peptides, processes for their preparation and uses thereof |
July 11, 2006 |
| The invention relates to new basic amino acid derivatives of general formulae I, II and III, and the preparation and use thereof in treatment of pain. The compounds have histogranin-like antinociceptive, morphine potentiating and COX-2 induction modulating activities. ##STR00001## wh |
| 7049429 |
Mutations of the 5' region of the human 5-HT1A gene |
May 23, 2006 |
| Clinical response to antidepressant compounds correlates with a selective down-regulation of presynaptic 5-HT1A receptors in serotonergic raphe neurons. Thus regulation of the 5-HT1A receptor gene could play a crucial role in the treatment or etiology of major depression. The promoter an |
| 6994957 |
Use of neuronal apoptosis inhibitor protein (NAIP) |
February 7, 2006 |
| The invention provides NAIP nucleic acid and sequences. Also provided are anti-NAIP antibodies and methods for modulating apoptosis and detecting compounds which modulate apoptosis. |
| 6977158 |
Mammalian IAP gene family, primers, probes, and detection methods |
December 20, 2005 |
| Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and |
| 6972281 |
Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof |
December 6, 2005 |
| The invention relates to new basic amino acid derivatives of general formula I and the preparation and use thereof in treatment of pain. The compounds have histogranin-like antinociceptive, morphine potentiating and COX-2 induction modulating activities. ##STR1##wherein: A is -hyd |
| 6898013 |
Optical transpose system |
May 24, 2005 |
| An optical transpose system has an array of multiplexing mesolenses (3) and an array of demultiplexing mesolenses (5) with a macrolens (4) positioned between them. |
| 6855692 |
Histogranin peptides and their analgesic use |
February 15, 2005 |
| The invention relates to linear and cyclic peptide and pseudopeptide compounds useful as analgesics, pharmaceutical compositions comprising such compounds, the use of the compounds and the compositions in the treatment of pain, and commercial packages containing such compounds and co |
| 6827830 |
Electrophoretic nucleic acid purification method |
December 7, 2004 |
| An electrophoretic method for purifying a nucleic acid sample is disclosed. According to the method, the electrophoresis is effective to substantially reduce the concentration of contaminants relative to the concentration of desired nucleic acid in the nucleic acid sample, thereby produc |
| 6797473 |
Methods and compounds for modulating male fertility |
September 28, 2004 |
| The invention features methods and reagents useful for the treatment of excessive or insufficient apoptosis in cells, and, particularly, in germ-line cells. The invention is useful in treating testicular cancers, cancers of germ-line cells, cancers in non-germ-line cell tissues, infe |
| 6765091 |
Oligosaccharides derived from ribose-ribitol-phosphate, and vaccines containing them |
July 20, 2004 |
| The present invention relates to the field of the Medicine, in particular with the chemical synthesis of oligosaccharide mixtures derived of ribose-ribitol-phosphate, which are used as active principle in vaccines for the prevention of infections caused by Haemophilus influenzae type b |
| 6673917 |
Antisense IAP nucleic acids and uses thereof |
January 6, 2004 |
| The present invention feature antisense IAP nucleic acids and other negative regulators of the IAP anti-apoptotic pathway, and methods for using them to enhance apoptosis. |
| 6645715 |
Artificial cornea |
November 11, 2003 |
| The invention provides an in vitro avascular human corneal equivalent that comprises immortalized human cell lines. As these corneal equivalents are in vitro models, they are maintained in an incubator throughout the testing period, thereby eliminating the problems and expense associated |
| 6566327 |
Histogranin peptides and their analgesic use |
May 20, 2003 |
| The invention relates to linear and cyclic peptide and pseudopeptide compounds useful as analgesics, pharmaceutical compositions comprising such compounds, the use of the compounds and the compositions in the treatment of pain, and commercial packages containing such compounds and co |
| 6486263 |
Method for producing saturated polymers and saturated or unsaturated blends |
November 26, 2002 |
| The present invention provides a method to improve the efficiency of ROMP-hydrogenation and ROMP-hydrogenolysis processes. Thus the invention provides a means for increasing the rate of reaction of the hydrogenation step of the ROMP-hydrogenation process via the addition of non-inert |
| 6429011 |
Neuronal apoptosis inhibitor protein gene sequence and mutations causative of spinal muscular at |
August 6, 2002 |
| The gene for autosomal recessive neurodegenerative disorder Spinal Muscular Atrophy has been mapped to a region of chromosome 5. The gene encodes a protein having homology with apoptosis inhibitor proteins of viruses so that the encoded protein has been labelled as a neuronal apoptosis |
| 6331412 |
Methods and compounds for modulating male fertility |
December 18, 2001 |
| The invention features novel methods and reagents useful for the treatment of excessive or insufficient apoptosis in cells, and, particularly, in germ-line cells. The invention is useful in treating testicular cancers, cancers of germ-line cells, cancers in non-germ-line cell tissues, |
| 6159948 |
Therapeutic and drug screening methods for the treatment and prevention of neuronal disease |
December 12, 2000 |
| NAIP and IAP polypeptides prevent neuronal cell death caused by ischemia, neurodegenerative conditions, and axotomy. The invention provides methods for neuroprotection by the prevention of cell death and kits and methods for the identification of neuroprotective therapeutic compounds. |
| 6156535 |
Mammalian IAP gene family, primers, probes, and detection methods |
December 5, 2000 |
| Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and |
| 6052420 |
Adaptive multiple sub-band common-mode RFI suppression |
April 18, 2000 |
| A noise suppression circuit for a two-wire communications channel comprises a hybrid device, for example a hybrid transformer or circuit, for providing a differential mode signal corresponding to a differential signal received from the two-wire channel. A summing device extracts from |
| 5954966 |
Membrane composition and method of preparation |
September 21, 1999 |
| The present invention relates to membranes useful in the separation of water from a solution containing volatile organic compounds and water. The membranes may be used in dehydrating an organic/water mixture to purify an organic when an organic is of interest or, alternatively, producing |
| 5928473 |
Inhibition of photo-yellowing in paper |
July 27, 1999 |
| The present invention relates to a method for the inhibition of photo-yellowing in paper rich in lignin by treatment of pulp or paper rich in lignin with a compound containing hydroxy functionalities that are capable of forming a ketal with a carbonyl group in an acidic environment. |
| 5919912 |
Mammalian IAP antibodies and diagnostic kits |
July 6, 1999 |
| Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and |
| 5858646 |
Modified HIV-pol polypeptide having immunological activity for use as diagnostic reagent |
January 12, 1999 |
| A polypeptide having immunological activity for use as a diagnostic reagent for the HIV. The polypeptide comprises a substantial portion of each of more than one of the constituent proteins coded for by the HIV-pol gene, namely the amino acid sequences of the reverse transcriptase, RNase |
| 5783194 |
Homogeneous isolate of urabe mumps virus and vaccines containing the isolate |
July 21, 1998 |
| A new attenuated substantially homogeneous Urabe mumps virus strain characterized by having a codon encoding glutamic acid at amino acid position 335 of the haemagglutinin-neuraminidase (HN) protein is provided. The codon may be GAA resulting in the abolition of an MseI restriction e |
| 5469277 |
Optical interconnection device |
November 21, 1995 |
| In N.times.N optical couplers, such as are used in local area networks and backplanes of telecommunications and computer equipment, which use BRAGG volume diffraction means to couple light beams between the inputs and outputs, the number of gratings is reduced by means of so-called "grat |
| 5457229 |
Process for preparing isocyanates from urethanes by a novel technique |
October 10, 1995 |
| Urethanes are converted to isocyanates by reaction with a chloro-, bromo- or iodo-borane compound and a tertiary amine in a nonpolar solvent. With the preferred borane compound, chlorocatecholborane, the reaction goes speedily and under gentle conditions to give the isocyanate in good yi |
| 5214105 |
Preparation of graft copolymers from macromolecules containing reactive tertiary structures |
May 25, 1993 |
| Novel styrene derivatives are disclosed of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each represents a saturated aliphatic hydrocarbon group or an aromatic hydrocarbon group, and R.sub.3 is --OH, Cl, or a group of the formula --OR.sub.4 or ## |
| 5210148 |
Styrenic polymer containing polyisobutylene side-chains |
May 11, 1993 |
| Novel styrene derivatives are disclosed of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each represents a saturated aliphatic hydrocarbon group or an aromatic hydrocarbon group, and R.sub.3 is --OH, Cl, or a group of the formula --OR.sub.4 or ## |
| 5194376 |
Baculovirus expression system capable of producing foreign gene proteins at high levels |
March 16, 1993 |
| A baculovirus expression system capable of producing foreign gene proteins at high levels. The system involves the production of a recombinant baculovirus containing a modified foreign gene between the polyhedrin gene promoter region and the transcription termination signal of the polyhe |
| 5192661 |
Multicomponent kit containing an antibody to a synthetic antigen of sialic acid |
March 9, 1993 |
| A compound X-Y wherein X comprises sialic acid, a sialic acid derivative or and oligosaccharide terminating in a sialic acid or sialic acid derivative if multibranched at the end of at least the largest branch, and, Y represents coupling means which allows an antibody to be raised to X w |
| 5179605 |
Optical interconnection device |
January 12, 1993 |
| An optical interconnection device suitable for an N.times.N' coupler as used, for example, in a local area network, comprises diffraction means in the form of a body having a refractive index which varies spatially and periodically in one plane of the body. The arrangement is such that l |
| 5084522 |
Styrenic polymer containing pendant reactive tertiary structures and the preparation thereof |
January 28, 1992 |
| Novel styrene derivatives are disclosed of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each represents a saturated aliphatic hydrocarbon group or an aromatic hydrocarbon group, and R.sub.3 is --OH, Cl, or a group of the formula --OR.sub.4 or ## |
| 5034516 |
Synthetic antigens of sialic acid and derivatives thereof |
July 23, 1991 |
| A compound X-Y wherein X comprises sialic acid, a sialic acid derivative or an oligosaccharide terminating in a sialic acid or sialic acid derivative if multibranched at the end of at least the largest branch, and, Y represents coupling means which allows an antibody to be raised to X wh |
| 4720839 |
Efficiency data transmission technique |
January 19, 1988 |
| Partial response and quadrature partial response data transmission system characterized by increased transmission rate, lower signal-to-noise ratio, low cost and simpler hardware implementation than prior art systems. A steep filter (almost rectangular) is connected to the output of a co |
