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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
University of Massachusetts Patents
Assignee:
University of Massachusetts
Address:
Boston, MA
No. of patents:
368
Patents:


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Patent Number Title Of Patent Date Issued
PP22085 Cactaceae plant named `Gail Glazier` August 16, 2011
A plant variety of the Cactaceae family, Schlumbergera truncata, called `Gail Glazier` having a predominantly white colored bloom characterized as R.H.S 155 D (white group). The new variety has a strong resistance to bud abscission, a strong propensity for buds to mature and flower, an
PP18221 Cactaceae plant named `Elsie` November 20, 2007
A variety of the Cactaceae family produced in a controlled hybridization `Elise`. The variety possesses the desirable characteristics of: a strong growth habit with erect stems; a red colored bloom; relatively large flowers; a strong propensity to branch with minimal pruning; and flowers
PP18177 Cactaceae plant named `Harmony` November 6, 2007
A plant variety of the Cactaceae family, Schlumbergera truncata, called `Harmony` having a deep colored bloom characterized as R.H.S. 46 B (red group). The new variety has a strong resistance to bud abscission, a strong propensity for buds to mature and flower, an erect growth habit,
PP16678 Boltonia plant named `Masbolimket` June 20, 2006
A new and distinct cultivar of Boltonia plant named `Masbolimket` characterized by its single inflorescence form, violet-colored ray florets, yellow-colored disc florets, dark green-colored foliage, freely branching character, and medium upright growth habit.
PP15378 Cactaceae plant named `Rio` November 30, 2004
A variety of the Cactaceae family produced by a controlled cross named `Rio`. `Rio` has a strong growth habit, a "red" colored bloom, a strong propensity to branch with minimal pruning, erect stems, and blooming flowers that last for two weeks on the plant.
PP11327 Cactaceae plant named `Avalon` April 4, 2000
A new and distinct plant variety of the Cactaceae family arising as a spontaneous mutation of Hatiora.times.graeseri `Evita`, is distinguishable from its progenitor and related varieties by its larger flowers, larger pollen grains, larger and thicker phylloclades, reduced branching, and
8586559 Spinal muscular atrophy (SMA) treatment via targeting of SMN2 splice site inhibitory sequences November 19, 2013
The present invention is directed to methods and compositions capable of blocking the inhibitory effect of a newly-identified intronic inhibitory sequence element, named ISS-N1 (for "intronic splicing silencer"), located in the SMN2 gene. The compositions and methods of the instant i
8586081 Detoxified recombinant botulinum neurotoxin November 19, 2013
The present invention relates to the isolation of polypeptides derived from the Clostridium botulinum neurotoxin and the use thereof as immunogens for the production of vaccines and antitoxins, as well as research and drug development applications. Clostridium botulinum is responsibl
8580275 Drug delivery product and methods November 12, 2013
The present invention provides a particulate delivery system comprising an extracted yeast cell wall comprising beta-glucan, a payload molecule and a payload trapping molecule. The invention further provides methods of making and methods of using the particulate delivery system.
8580270 Respiratory synctial virus (RSV) sequences for protein expression and vaccines November 12, 2013
The invention provides RSV fusion (F) protein ectodomain polypeptide sequences and nucleotide sequences encoding them, as well as cells containing the invention's polypeptide and nucleotide sequences. The invention further provides VLPs that contain the invention's polypeptides, and
8574900 Nucleic acid silencing sequences November 5, 2013
The present invention features compositions and methods for introducing, into cells, nucleic acids whose expression results in chromosomal silencing. The nucleic acids are targeted to specific chromosomal regions where they subsequently reduce the expression of deleterious genes, or
8299964 System and method for adaptive correction to phased array antenna array coefficients through dit October 30, 2012
A system and method of adaptively correcting the excitation or receive coefficients for a phased array antenna. For a transmitting antenna, a sensor located in the near field of the antenna is used to sense the antenna transmission. A reference signal that represents the sensor respo
8283076 Microbial fuel cells October 9, 2012
A microbial fuel cell is provided according to embodiments of the present invention including electricigenic microbes containing at least about 0.075 milligrams of protein per square centimeter of the anode surface area. In particular embodiments, the electricigenic microbes are disposed
8278271 Inhibiting collagen-induced platelet aggregation and activation with peptide variants October 2, 2012
The present invention provides peptides consisting of L- and/or D-amino acids and combinations thereof, which affect platelets by action on the collagen receptor, glycoprotein VI (GPVI). More specifically, however, the peptides act on the GPVI-FcR.gamma. signaling complex. The invention
8277657 Systems and methods for microbial reductive dechlorination of environmental contaminants October 2, 2012
In preferred embodiments, bioremediation systems are provided that comprise electricigenic microbes that use electrons provided directly from the anode of an electrical bioremediation system to carry out reductive dehalogenation of halogenated hydrocarbon contaminants, including chlo
8277643 Catalytic pyrolysis of solid biomass and related biofuels, aromatic, and olefin compounds October 2, 2012
This invention relates to compositions and methods for fluid hydrocarbon product, and more specifically, to compositions and methods for fluid hydrocarbon product via catalytic pyrolysis. Some embodiments relate to methods for the production of specific aromatic products (e.g., benzene,
8268965 Template-directed assembly of receptor signaling complexes September 18, 2012
Transmembrane receptors in the signaling pathways of bacterial chemotaxis systems influence cell motility by forming noncovalent complexes with the cytoplasmic signaling proteins to regulate their activity. The requirements for receptor-mediated activation of CheA, the principal kina
8263709 Crystal nucleating agents, crystalline polymer composition, methods of manufacture thereof, and September 11, 2012
A polymer composition, including: a first copolymer, including a first monomer unit derived from a monomer of Formula A: (R.sup.1SiO.sub.1.5).sub.x(R.sup.2SiO.sub.1.5).sub.y Formula A wherein R.sup.1 is a polymerizable functional group, R.sup.2 is a non-polymerizable group, x is a p
8257709 Antibodies against Clostridium difficile toxins and uses thereof September 4, 2012
Antibodies that specifically bind to toxins of C. difficile, antigen binding portions thereof, and methods of making and using the antibodies and antigen binding portions thereof are provided herein.
8251915 Dermal punch device August 28, 2012
A dermal punch for extracting skin or tissue samples. The dermal punch has a blade having a pair of walls. Each wall is convex and opens towards each other. The walls are connected to each other at a pair of mating edges. Each wall has a cutting edge. In a preferred embodiment, the ratio
8250903 Biological particle collector and method for collecting biological particles August 28, 2012
Provided are devices and methods for the collection of bioaerosols (such as viruses, bacteria, and proteins) from the exhaled breath of humans and/or animals, for the purpose of determining, for example, particle size, generation rate, diseases and interventions for particle release.
8244733 Adaptive hybrid reasoning decision support system August 14, 2012
A method for indexing a plurality of nodes using a computer system is provided. The computer system includes data storage and a processor coupled to the data storage. The method includes acts of storing the plurality of nodes in the data storage, each of the plurality of nodes having
8236311 Antibodies against clostridium difficile toxins and uses thereof August 7, 2012
Antibodies that specifically bind to toxins of C. difficile, antigen binding portions thereof, and methods of making and using the antibodies and antigen binding portions thereof are provided herein.
8232260 In vivo production of small interfering RNAs that mediate gene silencing July 31, 2012
The invention provides engineered RNA precursors that when expressed in a cell are processed by the cell to produce targeted small interfering RNAs (siRNAs) that selectively silence targeted genes (by cleaving specific mRNAs) using the cell's own RNA interference (RNAi) pathway. By i
8231861 Pancreatitis July 31, 2012
The present invention provides methods of identifying candidate therapeutic agents for use in the treatment of acute pancreatitis.
8226952 Human antibodies against rabies and uses thereof July 24, 2012
Human monoclonal antibodies that specifically bind to rabies virus, antigen binding portions thereof, and methods of making and using such antibodies and antigen binding portions thereof for treating rabies virus in a subject, are provided herein.
8217169 Coupling agents for peptide synthesis July 10, 2012
The present invention is directed to compounds of the formula: ##STR00001## or salts thereof or N-oxides and their use in peptide synthesis.
8216550 Luciferins July 10, 2012
Novel luciferins, methods of making luciferins, and uses of the same are disclosed.
8212019 Nucleic acid silencing sequences July 3, 2012
The present invention features compositions and methods for introducing, into cells, nucleic acids whose expression results in chromosomal silencing. The nucleic acids are targeted to specific chromosomal regions where they subsequently reduce the expression of deleterious genes, or
8204224 Wireless network security using randomness June 19, 2012
The present invention provides systems and methods for securing communications in a wireless network by utilizing the inherent randomness of propagation errors to enable legitimate users to dynamically create a shared symmetric secret key. In one embodiment, the invention provides a
8199048 Calibration technique for phased array antennas June 12, 2012
A method for calibrating a phased-array antenna that involves transmitting a signal from a transmitting element, and sequentially receiving the transmitted signal at two receiving elements each spaced a first distance from the transmitting element. This step is then repeated one or m
8198368 Cleavable block copolymers, functionalized nanoporous thin films and related methods of preparat June 12, 2012
Cleavable, disulfide-coupled block copolymers as can be used in the preparation of nanoporous thin films, micellar configurations and related structures.
8179026 Nanotubes, nanorods and nanowires having piezoelectric and/or pyroelectric properties and device May 15, 2012
Disclosed herein is a device comprising a pair of electrodes; and a nanotube, a nanorod and/or a nanowire; the nanotube, nanorod and/or nanowire comprising a piezoelectric and/or pyroelectric polymeric composition; the pair of electrodes being in electrical communication with opposin
8174703 Method for fabricating a sensor, a sensor, and a method for sensing May 8, 2012
A method for fabricating a sensor, a sensor so fabricated, and a method for sensing a stimulus are provided. The method includes providing an elongated open channel, such as, a V-groove, in a substrate, the open channel providing a first surface; removing at least some material from
8173618 Formulations for reducing neuronal degeneration May 8, 2012
Nutriceutical and pharmaceutical formulations for treating neurodegenerative disorders such as Alzheimer's disease are provided. Nutriceutical formulations include two or more of folate, vitamin E, and acetyl-L-carnitine (ALCAR). Pharmaceutical formulations include two or more of 3-d
8158742 Deoxybenzoin-based anti-flammable polyphosphonate and poly(arylate-phosphonate) copolymer compou April 17, 2012
Deoxybenzoin-phosphonate and other copolymer compounds, compositions and related methods.
8153739 Antimicrobial polymers April 10, 2012
The invention generally relates to novel polymers (SMAMPs) and their syntheses and use. The polymers exhibit promising properties of AMPs. In particularly, for example, a ring-opening metathesis polymerization (ROMP) platform was developed that allows syntheses of SMAMPs that employ
8153393 Spirolactam targeting compounds and related compounds April 10, 2012
Spirolactam targeting compounds, related compounds, uses of such compounds, and methods of making such compounds are disclosed.
8147428 Device and method for quantifying edema April 3, 2012
The preferred embodiments of the present invention are directed at a device that provides a reliable, accurate and quantifiable measure of a patient's edema. The device improves on the current method of digital manipulation by evaluating the pitting phenomena in a user-independent ma
8143339 Nanocomposite polymers March 27, 2012
Nanocomposite compositions containing a graft polymer and a filler such as nano-sized silica having flame resistant properties are described.
8137728 Biopolymer encapsulation and stabilization of lipid systems and methods for utilization thereof March 20, 2012
An emulsion system and method for controlling the digestion of a fat or an oil component is provided including a substantially hydrophobic food-grade component, and at least one of an emulsifier component, and one or more of polymeric components, wherein at least one of the emulsifie
8124349 Toll-like receptor assays February 28, 2012
Methods of identifying compounds that modulate the interaction between a TLR and a molecule that interacts with the TLR by direct binding or by inclusion in a complex that associates with the TLR are described. Methods of identifying molecules that interact with a TLR are also descri
8117902 Nanopatterned surfaces and related methods for selective adhesion, sensing and separation February 21, 2012
The invention is comprised, in part, of a surface that contains more than one component or construct. Such heterogenous surface compositions and configurations, related systems and methods for sensing particle or analyte interaction therewith can selectively and/or differentially int
8110560 Spinal muscular atrophy (SMA) treatment via targeting of SMN2 splice site inhibitory sequences February 7, 2012
The present invention is directed to methods and compositions capable of blocking the inhibitory effect of a newly-identified intronic inhibitory sequence element, named ISS-N1 (for "intronic splicing silencer"), located in the SMN2 gene. The compositions and methods of the instant i
8101586 Methods and compositions for the treatment of sterile inflammation January 24, 2012
Described are methods and compositions that inhibit IL-1 signalling for the treatment of acute inflammatory response to cell necrosis, and the attendant collateral tissue damage.
8101577 Oxidative DNA damage protection January 24, 2012
Provided herein are methods of screening compounds, gene sequences, and gene products in bacteria for agents that are protective against oxidative DNA damage in a human or animal. Gene sequences identified by these screens can also be used in diagnostic assays that identify subjects
8096786 Three dimensional micro-fluidic pumps and valves January 17, 2012
A system is disclosed for the control of fluid flow in a micro-fluidic system, the system having: a substrate; at least one micro-fluidic channel having disposed in a microchannel layer atop the substrate; a conformable layer disposed on the micro-fluidic layer; a receiving cavity di
8093223 RIP140 regulation of diabetes January 10, 2012
Inhibition of RIP140 increases glucose transport. Compounds that inhibit RIP140 expression or activity are useful for treating disorders associated with aberrant glucose transport (e.g., diabetes), treating obesity, increasing metabolism (e.g., fatty acid metabolism), and increasing
8084589 Phosphoramidite nucleoside analogs December 27, 2011
Described are phosphoramidite nucleoside analog monomers, precursors thereof, and oligonucleotides including one or more of the monomers. The monomers can be used during automated synthesis of oligonucleotide derivatives, and allow for incorporation of one or several reporter groups,
8084057 Compositions and methods for wound healing December 27, 2011
The present invention is related to the field of wound healing or tissue regeneration due to disease (i.e., for example, cardiovascular diseases, osteoarthritic diseases, or diabetes). In particular, the present invention provides compositions and methods comprising molecules with li
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