| Patent Number |
Title Of Patent |
Date Issued |
| RE39270 |
Process for continuous optimized protein production in insect larvae |
September 5, 2006 |
| The present invention provides for a recombinant insect larvae and a process of manufacturing proteins utilizing insect larvae that allows for the selection of individual larvae for harvest at the point of their optimal expression of a protein of interest. This invention also provides |
| 7407790 |
Recombinant double-stranded RNA phages and uses thereof |
August 5, 2008 |
| The present invention provides recombinant double stranded RNA phages (rdsRP) that express dsRNA-encoded genes in eukaryote cells. Recombinant dsRNA phages are useful for the expression of dsRNA expression cassettes encoding passenger genes, such as, but not restricted to, vaccine an |
| 7399473 |
Virus coat protein/receptor chimeras and method of use |
July 15, 2008 |
| The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can inter-act with each other to form a complex that is capable of binding a co-receptor. Such chimeric molecules therefore exhibit functional properties characteristic of a rece |
| 7384641 |
Immuno-modulating effects of chemokines in DNA vaccination |
June 10, 2008 |
| The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine. |
| 7375404 |
Fabrication and integration of polymeric bioMEMS |
May 20, 2008 |
| A micro-electro-mechanical system (MEMS) device is provided, along with means for its fabrication and operation for microfluidic and/or biomicrofluidic applications. The MEMS device includes a substrate, optional electrodes on the substrate, a patterned structure on the substrate, th |
| 7314741 |
Anaerobic ammonium oxidation for water treatment in recirculating aquaculture |
January 1, 2008 |
| Disclosed herein are planctomycetes sp. which convert ammonia to nitrogen under anaerobic conditions, filtration and aquaculture systems comprising said bacteria, filtration media comprising said bacteria, and methods of filtration using said bacteria. |
| 7311920 |
Virus coat protein/receptor chimeras and methods of use |
December 25, 2007 |
| The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can interact with each other to form a complex that is capable of binding a co-receptor. Such chimeric molecules therefore exhibit functional properties characteristic of a recep |
| 7247432 |
Enhanced protein thermostability and temperature resistance |
July 24, 2007 |
| Small heat shock proteins, e.g., Pyrococcus fuiosus (Pfu-sHSP and/or Pfu-tsHSP), confer thermotolerance on cellular cultures and on proteins in cellular extracts during prolonged incubation at elevated temperature, demonstrating the ability to protect cellular proteins and maintain c |
| 7244432 |
Infectious bursal disease virus (IBDV) variant from Georgia |
July 17, 2007 |
| A VP2 protein isolated from a variant Georgia strain of Infectious Bursal Disease Virus (IBDV) and method of generating such VP2 protein and variant strain for use to reduce or prevent infection in poultry by IBDV. |
| 7194978 |
Inducing sterility in fish by disrupting the development of the GnRH system |
March 27, 2007 |
| The present invention provides for a method for inducing sterility in fish by administering at least one compound that disrupts the establishment of the gonadotropin-releasing hormone system during early development thereby inhibiting sexual maturity in the treated fish. Effective co |
| 7138373 |
Polysaccharide-based polymers and methods of making the same |
November 21, 2006 |
| Gels and polymers comprising a polypeptide bound to a polysaccharide are disclosed. Specific polypeptides include, but are not limited to, polypeptides that comprise glutamine or tyrosine residues. Specific polysaccharides include, but are not limited to, chitosan. Gels and polymers |
| 7125718 |
Method for introducing and expressing genes in animal cells, and bacterial blebs for use in same |
October 24, 2006 |
| A method for introducing and expressing genes in animal cells, in which the animal cells are transfected with bacterial blebs containing a eukaryotic expression cassette encoding the gene. Bacterial blebs comprising a eukaryotic expression cassette, wherein the bacterial blebs are de |
| 7082893 |
Aquaculture nitrogen waste removal |
August 1, 2006 |
| The present invention relates to a two-stage biofilter reactor system for removing nitrogenous compounds from a recirculating aquaculture system. The system includes a aerobic nitrification unit and a downstream anaerobic denitrification unit, wherein both units have a mobile bed of |
| 7067145 |
Use of arachidonic acid for enhanced culturing of fish larvae and broodstock |
June 27, 2006 |
| A method of enhancing a culturing characteristic of fish larvae, including administering to said larvae in a nutritional diet essential fatty acids including DHA and AA in a ratio effective to enhance the culturing characteristic of such fish larvae relative to a corresponding nutrit |
| 7033767 |
Genes regulating programmed cell death |
April 25, 2006 |
| The present invention to amino acid sequences of proteins that are associated with apoptosis and the use of these proteins in the diagnosis, prevention and treatment of disorders associated with abnormal cell proliferation and apoptosis. The invention relates as well to nucleotide se |
| 6936256 |
Sub-unit vaccine for infectious pancreatic necrosis virus |
August 30, 2005 |
| The present invention relates to sub-unit vaccines comprising structural polypeptides of Infectious Pancreatic Necrosis Virus (IPNV) comprising structural proteins VP2 and VP3 folded as an empty IPNV viral capsid that approximates the size and structural conformation of native IPNV virus |
| 6919319 |
Immuno-modulating effects of chemokines in DNA vaccination |
July 19, 2005 |
| The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine. |
| 6908612 |
Virus coat protein/receptor chimeras and methods of use |
June 21, 2005 |
| The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can inter-act with each other to form a complex that is capable of binding a co-receptor. Such chimeric molecules therefore exhibit functional properties characteristic of a rece |
| 6841345 |
Treatment and prevention of immunodeficiency virus infection by administration of non-pyrogenic |
January 11, 2005 |
| The present inventors have found that certain preparations containing LPS and/or lipid A variants, derivatives, and/or analogs demonstrate non-pyrogenic properties and exhibit anti-viral activities. In particular, non-pyrogenic preparations of LPS, lipid A, LPS antagonists and lipid A |
| 6805882 |
Therapeutic fractions of sources of HCG |
October 19, 2004 |
| The present invention relates to fractions of sources and or preparations of human chorionic gonadotropin, such as fractions of human early pregnancy urine, which fractions have anti-HIV activity. The present invention further relates to pharmaceutical compositions comprising such fr |
| 6803479 |
Reagents and method for spatio-temporal control of gene expression by illumination |
October 12, 2004 |
| A caged non-steroidal ecdysome memetic (NSE) compound and a method for producing free NSE by subjecting the charged NSE to UV irradiation. |
| 6759241 |
Adjuvant comprising a lipopolysaccharide antagonist |
July 6, 2004 |
| LPS preparations, isolated from gram negative bacterial strains that contain at least one mutation in at least one of the htrB and msbB genes, and methods and therapeutics related thereto. The LPS preparations display both LPS antagonist and adjuvant activities. |
| 6759195 |
Method of differential display of prokaryotic messenger RNA by RTPCR |
July 6, 2004 |
| The present invention provides a method of differential display of prokaryotic messages RNA by RTPCR, the method comprising the steps of: adding a first primer mixture to a first nucleic acid sample including a first mixture of mRNA to form a first primer/first nucleic acid sample mi |
| 6699834 |
Method for treating cancer |
March 2, 2004 |
| The present invention relates to peptides of one or more portions of the human chorionic gonadotropin .beta.-chain as well as methods for treatment of cancer, using human chorionic gonadotropin, employing the .beta.-chain of human chorionic gonadotropin, peptides containing a sequence of |
| 6699656 |
Treatment and prevention of HIV infection by administration of derivatives of human chorionic go |
March 2, 2004 |
| The present invention relates to .beta.-hCG, particularly .beta.-hCG proteins having a sequence of amino acids 41-54, 45-54, 47-53, 45-57 and 45-58 and analogs and derivatives thereof. The invention further relates to methods of treatment and prevention of HIV infection by administration |
| 6660904 |
HIV and CD4 transgenic animals and uses therefor |
December 9, 2003 |
| The invention provides transgenic animals comprising a lentiviral transgene, such as an HIV transgene. Also within the scope of the invention are cells and eggs from the transgenic animal. Further included are methods for identifying therapeutic compounds for preventing lentiviral in |
| 6620985 |
PAD4 nucleic acid compositions from Arabidopsis and methods therefor |
September 16, 2003 |
| PAD4 compositions from Arabidopsis, including genomic and cDNA nucleic acid sequences, and methods for using said compositions in plants are provided. PAD4 from Arabidopsis is demonstrated to be regulatory and is required upstream from salicylic acid in the signal transduction pathway le |
| 6620416 |
Method for treating HIV |
September 16, 2003 |
| The present invention relates to peptides of one or more portions of the human chorionic gonadotropin .beta.-chain as well as methods for treatment and prevention of diseases, including HIV infection, using human chorionic gonadotropin, employing the .beta.-chain of human chorionic gonad |
| 6596688 |
Method for promoting hematopoiesis |
July 22, 2003 |
| The present invention relates to peptides of one or more portions of the human chorionic gonadotropin .beta.-chain as well as methods of promoting hematopoiesis, using human chorionic gonadotropin, employing the .beta.-chain of human chorionic gonadotropin, peptides containing a sequ |
| 6596477 |
Treatment and prevention of immunodeficiency virus infection by administration of non-pyrogenic |
July 22, 2003 |
| The present inventors have found that certain preparations containing LPS and/or lipid A variants, derivatives, and/or analogs demonstrate non-pyrogenic properties and exhibit anti-viral activities. In particular, non-pyrogenic preparations of LPS, lipid A, LPS antagonists and lipid A |
| 6596280 |
Method for generating birnavirus from synthetic RNA transcripts |
July 22, 2003 |
| A system for the generation of live Bimavirus such as infectious bursal disease virus (IBDV), a segmented double-stranded (ds) RNA virus of the Bimaviridae family, using synthetic transcripts derived from cloned DNA has been developed. Independent full-length cDNA clones were constructed |
| 6584935 |
Process for culturing crabs in recirculating marine aquaculture systems |
July 1, 2003 |
| The present invention relates to a recirculating marine aquaculture process for production of a crab species, including (i) a broodstock conditioning, (ii) spawning, (iii) egg incubation, (iv) larval growth, (v) nursery post-larval growth, and (vi) grow-out of the crab to a final product |
| 6579703 |
Enhanced protein thermostability and temperature resistance |
June 17, 2003 |
| Small heat shock proteins, e.g., Pyrococcus fuiosus (Pfu-sHSP), confer thermotolerance on cellular cultures and on proteins in cellular extracts during prolonged incubation at elevated temperature, demonstrating the ability to protect cellular proteins and maintain cellular viability und |
| 6569418 |
Immuno-modulating effects of chemokines in DNA vaccination |
May 27, 2003 |
| The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine. |
| 6563585 |
Ratiometric fluorometer |
May 13, 2003 |
| A method and apparatus for measuring the concentration of various analytes in a sample using native fluorescence is described. A first light source for producing a first light having a first wavelength is directed at the sample to produce a first emission from the sample, a second light |
| 6541235 |
Calcium free subtilisin mutants |
April 1, 2003 |
| Novel calcium free subtilisin mutants are taught, in particular subtilisins which have been mutated to eliminate amino acids 75-83 and part or all of amino acids 1-22 (the N-terminal region) and which retain enzymatic activity and stability. Recombinant methods for producing the same and |
| 6541234 |
Calcium free subtilisin mutants |
April 1, 2003 |
| Novel calcium free subtilisin mutants are taught, in particular subtilisins which have been mutated to eliminate amino acids 75-83 and which retain enzymatic activity and stability. Recombinant methods for producing same and recombinant DNA encoding for such subtilisin mutants are also |
| 6541208 |
Diagnostic method for distinguishing HIV-associated dementia from other forms of dementia |
April 1, 2003 |
| The HIV-1 transactivator protein Tat significantly increases astrocytic expression and release of monocyte chemoattractant protein-1. Monocyte chemoattractant protein-1 (MCP-1) is expressed in the brains of patients with HIV-1-associated dementia, and is present in the cerebrospinal flui |
| 6514979 |
Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monoph |
February 4, 2003 |
| Synergistic combinations of guanosine nucleoside analog reverse transcriptase inhibitors such as abacavir with inosine monophosphate dehydrogenase inhibitors such as mycophenolates, pharmaceutical compositions comprising such combinations, and therapeutic methods comprising administe |
| 6500419 |
Method for introducing and expressing RNA in animal cells |
December 31, 2002 |
| The invention pertains to a method for introducing RNA molecules into eukaryotic cells, wherein the RNA molecules are capable of being translated in the eukaryotic cells or is an antisense RNA or a catalytic RNA, as well as to such bacteria, compositions comprising such bacteria, and |
| 6479466 |
Compositions for treating viral infections, and methods therefor |
November 12, 2002 |
| Methods and combinations of an agent that promotes DNA synthesis in a virally-targeted cell and a nucleoside analogue having antiviral activity are provided for treating a viral infection in a subject in need thereof. Such compositions are particularly effective where the subject has |
| 6443097 |
Recirculating marine aquaculture process |
September 3, 2002 |
| A high efficiency recirculating marine aquaculture process for producing fish at variable yield densities of up to 60 kg/meter.sup.3 of the aquaculture tank, including fish that spawn under short photoperiods such as gilthead seabream (Sparus aurata) as well as fish that spawn under long |
| 6428970 |
Chemokine inhibition of immunodeficiency virus |
August 6, 2002 |
| The invention relates to therapeutic compositions and methods for treating and preventing infection by an immunodeficiency virus, particularly HIV infection, using chemokine proteins, nucleic acids and/or derivatives or analogs thereof. |
| 6426505 |
Phase-modulation fluorometer and method for measuring nanosecond lifetimes using a lock-in ampli |
July 30, 2002 |
| A low cost apparatus and method for measuring nanosecond luminescence lifetimes with a modulated LED light source that is driven by a lock-in amplifier. The lock-in amplifier provides both a DC bias and an AC signal used to modulate the intensity of an LED source light at a wavelength |
| 6399078 |
Chemokine--glycosaminoglycan complexes and their use in treating or preventing receptor mediated |
June 4, 2002 |
| The present invention provides therapeutic compositions of receptor ligand-containing antagonist complexes and methods of using them to treat diseases, disorders or conditions associated with the function or aberrant function of a cell surface receptor. |
| 6368604 |
Non-pyrogenic derivatives of lipid A |
April 9, 2002 |
| The present inventors have found that certain preparations containing LPS and/or lipid A variants, derivatives, and/or analogs demonstrate non-pyrogenic properties and exhibit anti-viral activities. In particular, non-pyrogenic preparations of LPS, lipid A, LPS antagonists and lipid A |
| 6326485 |
Assay for perkinsus in shellfish |
December 4, 2001 |
| The present invention is directed to oligonucleotides used as amplification primers and assay probes for species-specific detection and identification of the protozoan Perkinsus in shellfish. The oligonucleotides are designed to preferentially hybridize to what has been found to be a spe |
| 6319504 |
Treatment and prevention of HIV infection by administration of derivatives of human chorionic go |
November 20, 2001 |
| The present invention relates to .beta.-hCG, particularly .beta.-hCG proteins having a sequence of amino acids 41-54, 45-54, 47-53, 45-57 and 45-58 and analogs and derivatives thereof. The invention further relates to methods of treatment and prevention of HIV infection by administration |
| 6274147 |
Method for generating nonpathogenic infectious pancreatic necrosis virus (IPNV) from synthetic R |
August 14, 2001 |
| A system for the generation of live, nonpathogenic infectious pancreatic necrosis virus (IPNV), a segmented double-stranded (ds)RNA virus of the Birnavirdae family, using synthetic transcripts derived from cloned DNA has been developed. Independent full-length cDNA clones were constructe |
| 6261590 |
Methods for the enrichment of live feed with nutrients essential for fish larvae |
July 17, 2001 |
| A method of enriching fish food and live larval fish prey, especially Artemia nauplii and rotifers, with essentially highly unsaturated fatty acids, vitamins, amino acids, carotenoids and pigments. The live prey are allowed to ingest/adsorb dry soap powders of highly unsaturated fatty |
