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University of Kansas Patents
Assignee:
University of Kansas
Address:
Lawrence, KS
No. of patents:
80
Patents:


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Patent Number Title Of Patent Date Issued
8583296 Low-altitude altimeter and method November 12, 2013
A low-altitude altimeter (10) and a method of determining low altitudes for unmanned aerial vehicles (24). The altimeter includes at least two illuminators (12,14), at least one sensor (16), and a computing device (18). The illuminators (12,14) emit signals which are received by the
8568747 Enalapril compositions October 29, 2013
Provided herein are stable enalapril powder compositions for oral liquid formulation. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction
8293510 Method of preparing a hydrogel network encapsulating cells October 23, 2012
The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living cells, such as chondrocytes, encapsulated therein. In a preferred aspect, the physically cr
8278111 Metal abstraction peptide (MAP) tag and associated methods October 2, 2012
Compositions comprising a tripeptide having the sequence XC.sub.1C.sub.2; wherein X is any amino acid such that XC.sub.1C.sub.2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C.sub.1 and C.sub.2 are the same or differ
8268048 Oxygen binding of nanoparticulate metal complexes September 18, 2012
Solid nanoparticulate transition metal complexes of Co(II) salen exhibit reversible oxygen absorption in a near stoichiometric manner. In contrast, no measurable oxygen binding was observed with unprocessed Co(II) salen.
8263546 Prevention and treatment of osteoarthritis September 11, 2012
Subjects lacking Nfat1 display osteoarthritis in weight-bearing joints. Osteoarthritic changes associated with Nfat1 deficiency are characterized by articular cartilage degradation, articular chondrocyte proliferation/clustering, progressive articular surface destruction, periarticul
8252963 Nano-metal catalysts for polyol hydrogenolysis August 28, 2012
A catalyst composition can include: a support; a ruthenium catalyst (Ru) nanoparticle; and a linker linking the Ru nanoparticle to the support, wherein the linker is stable under hydrogenolysis conditions. In one aspect, the linker can include 3-aminopropyl trimethoxysilane (APTS) or
8252595 Metal abstraction peptide (MAP) tag and associated methods August 28, 2012
Compositions comprising a tripeptide having the sequence XC.sub.1C.sub.2; wherein X is any amino acid such that XC.sub.1C.sub.2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C.sub.1 and C.sub.2 are the same or differ
8251926 Pacifier system for studying and stimulating the human orofacial system August 28, 2012
The present subject matter is suited for evaluating biomechanics and electrophysiology of an infant's orofacial system during sucking. The present subject matter includes at least one orofacial sensor and a processor. In various examples, the present subject matter additionally inclu
8226579 Method and apparatus for measuring non-nutritive suck pattern stability July 24, 2012
Method and apparatus are provided for generating an index associated with non-nutritive suck pattern stability. A method includes measuring a plurality of non-nutritive suck (NNS) pressure samples, generating a plurality of correlation values using the NNS pressure samples, and gener
8212012 Novobiocin analogues having modified sugar moieties July 3, 2012
Novobiocin analogues useful as Hsp90 inhibitors in the treatment of cancer, neuroprotection, and autoimmune disorders.
8212011 Novobiocin analogues July 3, 2012
Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders, as well as cancer.
8193235 Compositions and methods for establishing and maintaining stem cells in an undifferentiated stat June 5, 2012
The present invention embraces compositions and methods for establishing and maintaining stem cells and inhibiting stem cell differentiation using a selective Protein Kinase C (PKC) inhibitor.
8192673 Resin systems for dental restorative materials June 5, 2012
The disclosure provides a new photopolymerizable resin system for dental restorative materials. The resin system utilizes a thiol-ene component as the reactive diluent in dimethacrylate systems. The ternary resin system comprises a thiol monomer, an ene monomer and a dimethacrylate monom
8188306 Heat shock protein 90 inhibitors May 29, 2012
Novel compounds useful for inhibiting the 90kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol.
8188218 Bi-functional peptides for multiple sclerosis treatment and diagnosis May 29, 2012
Novel bifunctional peptides useful in the treatment and/or diagnosis of EAE or MS. The peptides have a first peptide portion derived from an epitope of myelin proteolipid protein, myelin oligodendrocyte glycoprotein, or oligodendrocyte-specific peptide and a second peptide portion de
8183184 Polyelectrolyte complexes for oil and gas applications May 22, 2012
A polyelectrolyte complex for the controlled release of an oil and gas field chemical selected from the group consisting of (a) a gel-forming or cross-linking agent, (b) a scale inhibitor, (c) a corrosion inhibitor, (d) an inhibitor of asphaltene or wax deposition, (e) a hydrogen sulfide
8115029 Cobalt-catalyzed oxidations in volumetrically expanded liquids by compressed gases February 14, 2012
Oxidations of hydrocarbons, cycloalkanes and alkenes, arylalkanes, and a variety of other organic substrates are accomplished by cobalt-N-hydroxysuccinimide co-catalyzed reactions with dioxygen under unusually mild, near ambient conditions of temperature and pressure. The improved sa
8110402 Metal abstraction peptide (MAP) tag and associated methods February 7, 2012
Compositions comprising a tripeptide having the sequence XC.sub.1C.sub.2; wherein X is any amino acid such that XC.sub.1C.sub.2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C.sub.1 and C.sub.2 are the same or differ
8105625 Rapidly dissolving pharmaceutical compositions comprising pullulan January 31, 2012
The present invention provides an orally dissolving capsule comprising pullulan, a plasticizer and a dissolution enhancing agent.
8088412 Intralymphatic chemotherapy drug carriers January 3, 2012
A chemotherapeutic composition can be configured for subcutaneous administration for preferential intralymphatic accumulation while also providing a therapeutic systemic concentration that is not toxic. The composition can include a pharmaceutically acceptable carrier, and a nanoconj
8080677 Process for selective oxidation of olefins to epoxides December 20, 2011
A process for the selective oxidation of olefins to epoxides comprising the step of contacting the olefin (propylene or ethylene) with an oxidant (hydrogen peroxide) in the presence of a Lewis acid oxidation catalyst (MTO), organic base (pyridine or its N-oxide), in a solvent system
7993749 Nanoparticles comprising a nanoparticle template and a polymer shell having an amide side chain, August 9, 2011
Acid-labile poly(N-vinyl formamide) ("PNVF") nanocapsules were synthesized by free radical polymerization of N-vinyl formamide with optional active ingredients on the surface of silica nanoparticles. Polymerization in the presence of a novel cross-linker that contains an acid-labile
7960353 Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders June 14, 2011
Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders.
7856388 Financial reporting and auditing agent with net knowledge for extensible business reporting lang December 21, 2010
A system and method utilizes intelligent agents for searching, analyzing, and reporting business, financial, or non-financial information available through communication networks, particularly the Internet, regardless of inconsistencies in formats and granularity of that information. Thi
7811998 Novobiocin analogues as anticancer agents October 12, 2010
Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and ne
7786257 Signal-1/signal-2 bifunctional peptide inhibitors August 31, 2010
A novel peptide sequence having the general formula AB wherein each of A and B represent a chain of amino acid residues and wherein said A chain is capable of binding with a major histocompatibility complex on an antigen presenting cell, and wherein said B chain is capable of binding
7785605 Herpes simplex virus mutant ICP0 protein August 31, 2010
A mutant virus of herpes simplex virus type 1 (HSV-1) can include a mutant protein involved in replication so as to impair or inhibit replication of HSV-1. The mutant HSV-1 can have a mutation in at least one phosphorylation site of a protein involved in replication in order to inhib
7750813 Microstrip antenna for RFID device July 6, 2010
Microstrip patch antenna (46), feed structure (48), and matching circuit (50) designs for an RFID tag (10). A balanced feed design using balanced feeds coupled by a shorting stub (56) to create a virtual short between the two feeds so as to eliminate the need for physically connecting
7742152 Coherent detection scheme for FM chirped laser radar June 22, 2010
An optical homodyne detection scheme for FM chirped lidar is described. The system performs de-chirping within a photodetector, and it does not require high-speed photo-detection or RF mixing. Embodiments are also described for dealing with phase noise.
7649101 Process for selective oxidation of olefins to epoxides January 19, 2010
A process for the selective oxidation of olefins to epoxides comprising the step of contacting the olefin (propylene) with an oxidant (hydrogen peroxide) in the presence of a Lewis acid oxidation catalyst (MTO), organic base (pyridine or its N-oxide), in a solvent system comprising an
7644764 Polyelectrolyte complexes as delayed gelling agents for oil and gas applications January 12, 2010
A gel-forming composition for reducing the permeability of a subterranean formation or zone comprising a water soluble polymer (e.g., Alcoflood.RTM. 935) and a polyelectrolyte gelling agent comprising a polycation (e.g., polyalkylene imine) and a polyanion (e.g., dextran sulfate) is
7626391 High-throughput systems for magic-angle spinning nuclear magnetic resonance December 1, 2009
A solid-state nuclear magnetic resonance probe for use in a magnetic field having a plurality of isolated magic angle spinning modules positioned within the housing is disclosed. The housing is configured so that the plurality of magic angle spinning modules are located in a stationary
7622451 Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders November 24, 2009
Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders.
7608594 Novobiocin analogues as anticancer agents October 27, 2009
Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and ne
7605288 Heat shock protein 90 inhibitors October 20, 2009
Novel compounds useful for inhibiting the 90 kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol.
7602331 Computationally efficient adaptive radar pulse compression system October 13, 2009
One aspect of this disclosure relates to a method for processing a received, modulated radar pulse to resolve a radar target from noise or other targets. According to an embodiment of the method, a radar return signal is received and samples of the radar return signal are obtained. A
7598282 Neuroprotective agents October 6, 2009
Novel stereoisomers of GS-164 are provided. The compounds, such as (3R,5S,7as)-(3,5-bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a- -yl)methanol (TH-237A) and (3R,5S,7as)-(3,5-bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a- -yl)methanol (TH-242A) exhibit neuroprotec
7596545 Automated data entry system September 29, 2009
The present invention is a novel system and method for providing automated data entry of information. The system may include a processing subsystem capable of processing extensible markup language documents, a predicting subsystem capable of reviewing entered data of an input document an
7514463 Lonidamine analogues and their use in male contraception and cancer treatment April 7, 2009
Novel compounds useful for inhibiting spermatogenesis and cancer treatment, and in particular as inhibitors of heat shock proteins and/or elongation factor 1 alpha.
7459163 Infectious DNA as a vaccine against west nile and other flaviviruses December 2, 2008
A vaccine for West Nile virus that protects a subject against West Nile infection comprising an a pharmaceutically acceptable carrier and a therapeutically effective dose of an infectious agent selected from the group consisting of: a live attenuated infectious (+) RNA virus designat
7455842 Chimeric West Nile viruses and uses thereof November 25, 2008
A chimeric West Nile live virus comprised of the NY99 and WN1415 strains and an infectious DNA recombinant construct encoding for the chimeric virus are provided, as well as immunogenic compositions and their method of use.
7365234 Tuning product selectivity in catalytic hydroformylation reactions with carbon dioxide expanded April 29, 2008
An improved hydroformylation process is provided, which comprises reacting an olefin with CO and H.sub.2 in the presence of a hydroformylation catalyst in a liquid that has been volumetrically expanded with a compressed gas, such as supercritical carbon dioxide.
7345812 Method and apparatus for use of III-nitride wide bandgap semiconductors in optical communication March 18, 2008
The present disclosure relates to the use of III-nitride wide bandgap semiconductor materials for optical communications. In one embodiment, an optical device includes an optical waveguide device fabricated using a III-nitride semiconductor material. The III-nitride semiconductor mat
7244718 Water soluble prodrugs of hindered alcohols July 17, 2007
The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals.
7208630 Heat shock protein 90 inhibitors April 24, 2007
Novel compounds useful for inhibiting the 90 kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol.
6872838 Water soluble prodrugs of hindered alcohols March 29, 2005
The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals.
6819297 Wideband planar antenna November 16, 2004
An energy feed structure includes a first tube having an open end and a closed end, a second tube to pierce the closed end, and a solid dielectric material to cover the open end. An apparatus comprises a resonant element located in a first plane, a ground plane located in a second plane
6814845 Method for depositing an enzyme on an electrically conductive substrate November 9, 2004
Improved biosensors are provided having excellent selectivity and stability properties, together with methods of preparing the biosensors. A preferred biosensor includes an electrode (12) having enzyme (16) deposited thereon together with a layer of electropolymerized polymer (18) interm
6603015 Synthesis of epothilones August 5, 2003
Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment A and C precursors. Segment C precursors are prepared using starting nitriles, whic
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